巻号一覧
58 巻 (2011)
- 4 号 p. 99-
- 3 号 p. 73-
- 2 号 p. 41-
- 1 号 p. 1-
58 巻, 2 号
選択された号の論文の5件中1～5を表示しています
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Original Contribution
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TAKEFUMI YOSHIDA, YOSHITO AKAGI, TETSUSHI KINUGASA, ICHITARO SHIRATSUC ...2011 年 58 巻 2 号 p. 41-46
発行日: 2011/09/30
公開日: 2012/01/18
ジャーナル フリーClinicopathological characteristics and grading of poorly differentiated colon adenocarcinoma (Por) were discussed. A total of 1074 patients with colon cancer underwent surgical treatment at Kurume University Hospital in Fukuoka, between 1985 and 2005. Clinicopathological characteristics of 88 cases (8%) of Por and 986 cases (92%) of well differentiated tubular adenocarcinoma&fraslmoderately differentiated tubular adenocarcinoma (Tub1/Tub2) were studied. A multiple classification analysis showed that Por was more frequently observed in the right colon than Tub1/Tub2, and that the ratio of macroscopic types 3 and 4 was significantly higher in Por. Significant differences were also observed with regard to lymph vessel and perineural invasion. There were no significant differences between recurrence-free survivals of Por and Tub1/Tub2 after radical resection in Stages II and III. Recurrence of Por was significantly higher in peritonea and lymph nodes. These findings indicate that Por, which is generally considered to have a poor prognosis, has a similar recurrence rate to that of Tub1/Tub2 after the performance of radical surgery.抄録全体を表示PDF形式でダウンロード (709K) -
SHIN YAMASHITA, HIROSHI HASUO, TAKASHI TOKUTOMI, MINORU SHIGEMORI, TAK ...2011 年 58 巻 2 号 p. 47-58
発行日: 2011/09/30
公開日: 2012/01/18
ジャーナル フリーEffects of edaravone, a free radical scavenger, on post-traumatic impairment of long-term potentiation (LTP) were examined in granule cell layers of the dentate gyrus (DG) in vitro. Field EPSPs (fEPSPs) evoked by stimulation of the perforant path (PP) were recorded extracellularly in the DG one week after a moderate impact applied by a fluid percussion injury (FPI) device. High frequency stimulation (HFS) of the PP caused LTP of the fEPSP-slope in slices from naïve and sham-operated rats, however, the LTP was strongly depressed in slices from FPI rats. Intraperitoneal administration of edaravone 15 min after FPI prevented the hyperactivities of DG neurons and attenuated impairment of the LTP in FPI rat dentate granular cells. In vitro application of spermine NONOate (sp-NO), a nitric oxide (NO) donor, for 30 min produced a gradual increase in the fEPSP-slope, lasting for more than 2 h. Edaravone attenuated the enhancement of the fEPSP-slope induced by sp-NO. After sp-NO treatment HFS could not produce an obvious LTP in the DG granule cell layer. Pretreatment of DG slices with edaravone prevented the sp-NO-induced impairment of LTP. These results suggest that administration of edaravone after FPI protects against post-traumatic impairment of LTP in granule cell layers of the DG, possibly by scavenging NO-related radicals.抄録全体を表示PDF形式でダウンロード (1110K)
Case Report
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HABIB EMRE, YASEMIN USUL SOYORAL, SERHAT TANIK, ILHAN GECIT, HUSEYIN B ...2011 年 58 巻 2 号 p. 59-61
発行日: 2011/09/30
公開日: 2012/01/18
ジャーナル フリーRenal infarction (RI) is a rarely seen disorder, and the diagnosis is often missed. The two major causes of RI are thromboemboli originhating from a thrombus in the heart or aorta, and in-situ thrombosis of a renal artery. We report a case of RI that developed due to renal artery and vein thrombosis, as confirmed by pathological evaluation of the nephrectomy material, three weeks after renal cyst aspiration.抄録全体を表示PDF形式でダウンロード (2034K) -
TOSHIHIRO MATSUO, SHINZO TAKAMORI, NAOFUMI HAYABUCHI, MUTA FUMIHIKO, M ...2011 年 58 巻 2 号 p. 63-65
発行日: 2011/09/30
公開日: 2012/01/18
ジャーナル フリーLiposarcoma originating in the thoracic cavity is not common. It has been reported that neither chemotherapy nor radiotherapy is effective, and that surgical resection is the only therapeutic option. There have been several cases reported of a large liposarcoma compressing adjacent organs such as the lung and the heart. In such cases, careful management is required to prevent adverse cardiopulmonary events during resection. Here we report a rare case of a 52-year-old male who had a giant liposarcoma occupying the majority of the right thorax. The patient was placed in the supine position, and the tumor was resected through an anterior thoracotomy. Percutaneous cardiopulmonary support (PCPS) was prepared in case of need. However, we succeeded in resecting the huge tumor without use of PCPS. We were unable to completely resect the tumor because it originated from the posterior mediastinum and extended into the left thorax. The resected tumor weighed 3,500 g and was 28 cm in largest diameter. The postoperative course was uneventful, except for hypoxemia lasting a few days caused by re-expansion edema in the lung. The patient was discharged and is alive at five years to date.抄録全体を表示PDF形式でダウンロード (719K) -
MIKI TAKENAKA, UHI TOH, HIROKO OTSUKA, HIROKI TAKAHASHI, NOBUTAKA IWAK ...2011 年 58 巻 2 号 p. 67-72
発行日: 2011/09/30
公開日: 2012/01/18
ジャーナル フリーWe present a case of a 57-year-old woman with a giant malignant phyllodes tumor (PT) in her right breast, with maximum diameter of 20 cm. The core-needle and excisional biopsy specimens were diagnosed as suspicious for low-grade myofibroblastic sarcoma (LGMS). The subsequent total mastectomy with partial resection of the pectoral muscles showed predominance of stromal hypercellularity without an epithelial component. However, we diagnosed this as a malignant PT because focal areas showed a leaf-like pattern. In the case of large malignant PTs that exhibit stromal predominance, it can be difficult to distinguish between a pure sarcoma and malignant PT. It is important to thoroughly examine multiple sections from the view point of residual epithelial structure in morphological diagnosis.抄録全体を表示PDF形式でダウンロード (5101K)
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