The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
ISSN-L : 0023-5679
36 巻, 4 号
選択された号の論文の8件中1~8を表示しています
  • MARKUS FÄRKKILÄ, LEA LEINONEN
    1989 年 36 巻 4 号 p. 155-159
    発行日: 1990/03/31
    公開日: 2010/02/08
    ジャーナル フリー
    A patient with chronic relapsing polyneuropathy noticed that when he took some alcohol in the evening his muscle force increased substantially during the next day. To measure this beneficial effect of ethanol we measured the force of hand grip, conduction velocities and distal latencies of ulnar and median nerves, and the power spectra of EMG during maximal and submaximal hand grip before and after alcohol ingestion. A 50% increase in the muscle force was documented 24 hours after the alcohol administration, with a concomitant increase of high frequency components in the power spectrum of EMG. Slight decreases in distal latencies were also measured.
  • MARIKO OKI, TATSUYA ISHITAKE, AKI OHKUBO, TSUNETAKA MATOBA
    1989 年 36 巻 4 号 p. 161-166
    発行日: 1990/03/31
    公開日: 2010/02/08
    ジャーナル フリー
    Whole-body vibration suppresses the development of atherosclerosis in the rabbit (Oki and Matoba, 1987). The present study was designed to clarify whether the effect of vibration on atherosclerosis depends on the frequency of vibration. Longitudinal vibrations at a frequency of 30 or 60 Hz was applied to 12 New Zealand white rabbits for 12 weeks. The gradual decrease in body weight and blood hematocrit in the vibration groups with time were parallel to the changes in the controls. The rate of increase in serum lipid concentrations induced by a cholesterol-rich diet was significantly suppressed in the vibration groups, as compared to the controls. This may be due to the vibration and not the diet. The aortic wall was thinner at 60 Hz than at 30 Hz, whereas the ratios of trace metals (Ca/Mg and Zn/Cu) in the aortic tissues were smaller at 30 Hz. The area of plaque formation in the intima was smaller at 60 Hz than at 30 Hz (p<0.05). Thus, the suppressive effect of vibration on the development of atherosclerosis in the aorta may be greater at a frequency of 60 Hz than at 30 Hz. Vibration may play an important role in lipid metabolism.
  • JINRYO TAKEDA, KEN HASHIMOTO, KIKUO KOUFUJI, TOURU UMEZU, TAKAHO TANAK ...
    1989 年 36 巻 4 号 p. 167-172
    発行日: 1990/03/31
    公開日: 2010/02/08
    ジャーナル フリー
    From 1966 to 1985, 2130 patients with gastric cancer were admitted to our surgical department. Among these cancers, gastric cancer following partial gastrectomy for benign gastroduodenal lesion were present in 22(1%) patients. The original pathology was gastric ulcers in 64% (14 patients), duodenal ulcers in 23% (5 patients), combined gastric and duodenal ulcers in 9% (2 patients), and leiomyoma of the gastric cardia in 4% (1 patient). Fourteen patients were reconstructed by Billroth II, 7 by Billroth I, and one had an esophagogastrostomy after a proximal gastrectomy. The cancer in 19 (86%) patients was resected and 3(14%) could not be resected. Only 2(9%) were early cancer, 20(89%) were advanced cancer including 11(50%) with Borrmann type 3. A higher proportion of positive lymphnode metastasis was observed for residual gastric cancer (84%) than for primary gastric cancer (49%). The overall 5-year survival rate was 32%, with a 5-year survival rate of 45% for those who underwent curative resection.
  • KEIJI OKUBO, TADASHI KARASHIMA, HIROSHI HACHISUKA, YOICHIRO SASAI
    1989 年 36 巻 4 号 p. 173-179
    発行日: 1990/03/31
    公開日: 2010/02/08
    ジャーナル フリー
    We investigated the presence of a platelet-activating factor-like substance in blister fluid obtained from patients with bullous pemphigoid. Hu-man platelet aggregation activity was present in blister fluids obtained from 4 out of 6 patients with bullous pemphigoid and in blister fluids obtained from 3 cases with contact dermatitis. Platelet aggregation activity of pemphigoid blister fluids was inhibited by pretreatment with lyso-PAF, which is a precursor metabolite of platelet activating factor. The activity of blister fluids obtained from patients suffering from contact dermatitis was not inhibited by precursor. Blister fluids obtained from burn lesions and blisters of normal skin induced in the suction revealed no platelet aggregation activity. These results suggest that platelet-activating factor or a similar substance is present in the blister fluid obtained from suffered bullous pemphigoid.
  • JUNJI ISHIMATSU, MASAHIDE HOTTA, TAKAMOTO MATSUNAGA, AKIHIKO MANABE, O ...
    1989 年 36 巻 4 号 p. 181-184
    発行日: 1990/03/31
    公開日: 2010/02/08
    ジャーナル フリー
    Middle cerebral artery (MCA) blood flow velocity waveforms were recorded by a pulsed Doppler system in normal and small for dates (SFD) fetuses. Eighty four normal growth fetuses and 15 SFD fetuses were studied between the 28th and 40th gestational week. The flow velocity waveforms were analysed to determine the resistance index (RI=peak systolic velocity minus end diastolic velocity/peak systolic velocity). The results obtained were as follows : 1. The mean values of RI in the MCA had a peak of 0.802±0.049 at 32-33 gestational weeks and decreased gradually to a level of 0.686±0.087 at 40 gestational weeks. 2. In 8 asymmetrical SFD fetuses, the RI values for the MCA were below the normal range (mean -1.5 SD) in 6 cases and normal in 2 cases. 3. The RI values for MCA in all 7 symmetrical SFD fetuses were in the normal range.
  • TAKASHI NISHIDA, FRANCESCO DI RE, TORU SUGIYAMA, MICHIAKI YAKUSHIJI
    1989 年 36 巻 4 号 p. 185-187
    発行日: 1990/03/31
    公開日: 2010/02/08
    ジャーナル フリー
    A staging error can lead to a treatment failure in the management of patients with malignant diseases. The actual progression of endometrial carcinoma was postopertaively examined in twenty patients with clinical stage II disease classified by FIGO (International Federation of Gynecology and Obstetrics) criteria. In seven of 20 patients (35%), extrauterine lesions were revealed at surgery. These seven stage-up tumors included three grage 3 endometrioid cancers, three uterine papillary serous carcinomas (UPSC) and one grade 2 endometrioid tumor with deep myometrial invasion. The sites of the extrauterine lesions were determined. The grade 2 cancer was associated with parametrial invations and positive pelvic lymph nodes. One grade 3 endometrioid tumor and two UPSCs had positive periaortic lymph nodes. Omental involvements were revealed in one grade 3 cancer and two UPSCs, indicating that the pattern of spreading of endometrial cancer with a malignant histology is similar to the spreading of ovarian cancer. Since the both endometrium and ovarian surface epithelium have a common histologic origin in the early embryonic stage, a similar biological characteristics of these tumors are suggested. From the results, it is recommended that a radical hysterectomy with periaortic lymph node dissection, omentectomy and peritoneal washing cytology be performed for endometrial cancer with a malignant histology or deep myometrial invasion to obtain the actual staging which is necessary for maximal curative potential.
  • YOSHIHIKO ONIZUKA
    1989 年 36 巻 4 号 p. 189-197
    発行日: 1990/03/31
    公開日: 2010/02/08
    ジャーナル フリー
    A hyperthermia system which has been developed for clinical use is described. Five helical coil applicators operating at the microwave frequency of 2450 MHz were used for inducing hyperthermia in superficial tumors to the depth of approximately 5 cm in regions of extreme curvature (i, e, extremities, breasts, head and neck) by superimposing several beams from the multiple applicators. The microwave generators were controlled by a microcomputer governed by temperature measurements from thermocouple probes inserted into the tissue. This system was evaluated with respect to the local specific absorption rate (SAR) of the electromagnetic energy for two agar gel phantoms. The relationship of temperature versus depth in four patients was measured with 2-4 applicators (total, 250-600 Watt). Up to May, 1989, 70 patients with superficial tumors, esophageal cancer and carcinoma colli had been treated with radiotherapy combined and local hyperthermia using this system.
  • MASATOSHI ISHIBASHI, SEIICHIRO MORITA, SHUNJI NAKANO, YOUICHIRO SASAI, ...
    1989 年 36 巻 4 号 p. 199-204
    発行日: 1990/03/31
    公開日: 2010/02/08
    ジャーナル フリー
    Using N-isopropyl-(I-123)p-iodo-amphetamine (I-123 IMP) and gallium-67 citrate, it was possible to detect human malignant melanomas. I-123 IMP imaging was helpful in detecting melanomas occurring in the legs and arms, and the 4 hour image was better than the 1 hour image. Moreover, while gallium scintigraphy more clearly detects human malignant melanoma, I-123 IMP allows for the detection of human malignant melanoma within 1 hour after administration.
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