巻号一覧
35 巻 (1988)
- 4 号 p. 159-
- 3 号 p. 101-
- 2 号 p. 49-
- 1 号 p. 1-
35 巻, 3 号
選択された号の論文の8件中1～8を表示しています
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AKIHIRO KAGIYAMA, GENKO SHIN, HIROSHI UETA, TAKACHIKA SHOJI, SHIRO MIM ...1988 年 35 巻 3 号 p. 101-106
発行日: 1988/12/01
公開日: 2010/02/08
ジャーナル フリーTo determine the mechanism of adriamycin (ADR) induced cardiotoxicity, the effects of ADR on the Ca2+ uptake and release of cardiac mitochondria were investigated. Male Wistar rats were injected intraperitoneally with 4 mg/kg body weight of ADR for 6 consequtive days, and mitochondria were isolated from heart muscle. Ca2+ uptake and release of cardiac mitochondria were measured spectrophotometrically using a metallochromic dye antipyrylazo III. The total calcium content was determined by atomic absorption. ADR administration resulted in reductions of the Ca2+ uptake velocity, Na+-Ca2+ exchange velocity and the calcium content in cardiac mitochondria. The data reported here is useful for understanding the pharmacological effect of adriamycin to unfavourable side-effect, cardiotoxicity.抄録全体を表示PDF形式でダウンロード (689K) -
SHOJI YANO1988 年 35 巻 3 号 p. 107-116
発行日: 1988/12/01
公開日: 2009/08/11
ジャーナル フリーMedium chain dicarboxylic aciduria has been induced in fasted rats by 2-tetradecyloxiranecarboxylate (TDOC), a known inhibitor of carnitine: palmitoyltransferase I. Administration to fasted rats in dosages of 5 mg/kg or 30 mg/kg of body weight each day caused supression-in the expected fasting-induced enhancement of 3-hydroxybutyric acid excretion and an increase in the excretion of palmitic acid in the first 24 hour period of fasting, implying an in vivo inhibition of the mitochondrial β-oxidation of long chain fatty acids. Along with these effects, excretions of two medium chain dicarboxylic acids-sebacic and suberic acids-were also induced in the fasted rats. A similar dicarboxylic aciduria was found in non-fasted rats given 30 mg/kg of this inhibitor. Liver histology revealed microvesicular fatty change in the fasted, TDOC-loaded animals. The TDOC-induced medium chain dicarboxylic aciduria in rat is an effective model for correlation to impaired mitochondrial, β-oxidation in human.抄録全体を表示PDF形式でダウンロード (4870K) -
A Case ReportTETSUKO OKUNO, TORU TAKAMATSU, TOMOKO NAKANO, AKIO INOUE1988 年 35 巻 3 号 p. 117-121
発行日: 1988/12/01
公開日: 2009/08/11
ジャーナル フリーA severe case of multiple cartilaginous exostoses (MCE) was presented. The patient, a 10-year-old girl was the affected member of a family with paternal MCE transmitted over at least 3 generations. Her growth disturbance appeared to have resulted from the severe exostoses of the long bones.抄録全体を表示PDF形式でダウンロード (3944K) -
KEI MATSUOKA, KATSUYUKI NAKAGAWA, KOSAKU ETO1988 年 35 巻 3 号 p. 123-125
発行日: 1988/12/01
公開日: 2009/08/11
ジャーナル フリーA case of a foreign body stone which formed on an indwelling catheter that was left in the urinary bladder for a long time is described. Foreign body stones are composed primarily of a mixture of struvite and carbonate apatite, which are components of infection stones. The foreign body can be iatrogenic, accidentally or self-induced, or endogenous, suggesting that a variety of materials can serve as the nucleus for the stone.抄録全体を表示PDF形式でダウンロード (2125K) -
SHOJI YANO, MAKOTO YOSHINO, ATSUSHI NISHIYORI, MITSUYOSHI NAKAO, TORU ...1988 年 35 巻 3 号 p. 127-133
発行日: 1988/12/01
公開日: 2009/08/11
ジャーナル フリーThe cases of two patients with primary hyperoxaluria type I, aged five years and two years, born to consanguineous parents are described. These patients have been treated with oral pyridoxine hydrochloride at a dose of 200mg/24 hr without evidence that this regimen has decreased urinary oxalate excretion. Studies of oxalate excretion in the family members yielded results consistent with either autosomal dominant inheritance, with variable expressivity, or with autosomal recessive character.抄録全体を表示PDF形式でダウンロード (2015K) -
HIROYOSHI MIZOTE, LIN GU, MASAHARU SUGIYAMA, TERUO KAKEGAWA1988 年 35 巻 3 号 p. 135-138
発行日: 1988/12/01
公開日: 2009/08/11
ジャーナル フリーAn adult case of congenital segmental dilatation of the jejunum with malrotation was treated by resecting the dilated tract and performing an end-to-end anastomosis. The progress of this case was reported along with a review of the literature. 1) 9 cases of congenital segmental dilatation of the intestine with malrotation, including this case (Babut et al. 1977; Komi 1974; Kusaba et al. 1983; Rossi 1973; Swenson et al. 1959) have been reported . The relative morbidity for males and females was 2 : 7. The location in the jejunum was high in 6 cases. 2) the morbidity was the highest in infants . The etiology of this disease still remains unclear. 3) Differential diagnosis of this disease from Hiruschsprung's disease in infants and from mechanical ileus in adults is important. 4) With resection of the dilated tract and end-to-end anastomosis, g results can be obtained. This method is recognized as the best treatment. 5) The etiology of this disease is unknown. Physiological and biochemical research must be continued until the etiology is clarified.抄録全体を表示PDF形式でダウンロード (2456K) -
HIROYOSHI MIZOTE, MOTOKI FUKUDA, YOSHIAKI TANAKA, SHIGEKI HIKITA, NAOK ...1988 年 35 巻 3 号 p. 139-145
発行日: 1988/12/01
公開日: 2009/08/11
ジャーナル フリー37 cases of MOF were encountered during the past 5 years, accounting for 2.9% of all intestinal operation. Nutritional control for MOF from the pathophysiological points of view, especially control of sugar and protein metabolism were discussed.抄録全体を表示PDF形式でダウンロード (608K) -
EIICHIRO ONO1988 年 35 巻 3 号 p. 147-157
発行日: 1988/12/01
公開日: 2009/08/11
ジャーナル フリーAn outbreak of infantile papular acrodermatitis (IPA) occurred in and around Saga City from May 1977 through April 1978, infecting 26 patients. Over 50% of the patients were two years of age or younger. As most of the patients came from the same clinic, the source of the Hepatitis B virus infection was probably contaminated syringes used in that clinic. The 12 patients examined for subtype were all adw, whereas Ishimaru et al. (1976) reported that the subtype in Matsuyama was ayw. Apart from the Saga and Matsuyama outbreaks, the subtypes reported in 39 sporadic cases in various parts of Japan, including three sporadic cases which we experienced, were : adr, 25 cases (64%); adw, 10 cases (26%); ayr, 1 case (2%); and ayw, 3 cases (8%). This distribution pattern is similar to that for adult HBV carriers in Japan. It was confirmed that IPA was present in every HBsAg subtype, and therefore IPA was not subtype specific. Half of the patients (13/26) had maximum serum GOT levels over 1000 K. U. The average level was also much higher in the Saga patients than in the Matsuyama patients. HBs-antigenemia disappeared within 2 months after the onset of the disease in 46% of the patients, and within 3 months in 65% of the patients, whereas 5 of 26 or 19% still were positive HBsAg even after 6 years. Horizontal transmission to parents occurred in 7 cases (2 fathers and 5 mothers), and to siblings in 5 cases. The HBsAg positive rate was 23% (7/31) among the parents checked. This was significantly higher than the rate of 3% (10/358) found in a healthy population from a neighboring district (po= 0.0000).抄録全体を表示PDF形式でダウンロード (5362K)
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