JOURNAL OF THE KYORIN MEDICAL SOCIETY

[title in Japanese]

Article type: Cover
1990 Volume 21 Issue 3 Pages Cover9-
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.Cover9

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[title in Japanese]

Article type: Cover
1990 Volume 21 Issue 3 Pages Cover10-
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.Cover10

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Activation of B Cells in Peripheral Blood of Newborns and Premature Infants with Infection

Ren HASEGAWA

Article type: Article
1990 Volume 21 Issue 3 Pages 373-381
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.373

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To search for movements of peripheral B cells in newborns and premature infants suffering from infections, we evaluated the B5 antigen, a marker for B cells having potential activity for differentiation or proliferation, by determining the percent of B5-positive cells that appeared after mixed form lymphocyte cultures. Our study showed that B5-positive lymphocytes increased in number when taken during the recovery phase of the infection, indicating that peripheral B cells were active in this period. In mixed form lymphocyte cultures stimulated with Protein A, B cells differentiated mainly to B4 (CD 19)^+ cells and to a lesser extent, to B1 (CD 21)^+ cells. In peripheral blood of newborn and premature infant, the normal average value of B1 antigen-positive cells was 6.8% (±3.59 SD) ; and that for B4 antigen-positive ones, 7.3% (±3.42 SD).

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The Evaluation of Myocardial Involvement in Patients with Progressive Muscular Dystrophy of the Duchenne Type : A 5 Year Follow-up Study Using Two-dimensional Echocardiography

Shunkichi HIRATA

Article type: Article
1990 Volume 21 Issue 3 Pages 383-393
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.383

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Using the two-dimensional echocardiography (2-DE), myocardial involvement in progressive muscular dystrophy of Duchenne type (DMD) was observed over the period of 5 years. Total of 91 patients were subjected to evaluate including deceased 35 patients in the course of observation. Graded classification of skeletal muscle dysfunction accordingly to Swinyard-Deaver (S-D) was compared with wall motion index (WMI) of the left ventricle obtained by 2 DE, in each patients. The results indicated significant progress of the severity in both S-D classification (from 5.41±1.22 of first year value to 7.05±0.95 of 5th year value, P<0.01) and total WMI value (from 2.32±3.14 to 7.18±3.43, P>0.01) in 5-year period. As the regional change of the left ventricular WMI deteriorations were progress in the posterior WMI from 0.60±0.72 to 1.88±0.60 (P>0.01) in 5-year periode, lateral WMI from 0.11±0.29 to 0.51±0.63 (P>0.01) and apical WMI from 0.21±0.45 to 1.54 ±0.68 (P>0.01) respectively. Deteriorations of WMI was observed in cases of moderately or more advanced grade of S-D classification at the first year. However, the degree of deteriorations in regional WMI did not correlate well to the similar degree of deteriorations in the S-D classification on ocasion. Although the most common cause of death in DMD was respiratory failure (85%), higher WMI values were noted in them. Thus, the WMI obtained by 2 ED is useful in clinical evaluation of the myocardial involvement in DMD.

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Leiomyosarcoma of the Stomach with Exogastric Growth Diagnosed by Endoscopic Ultrasonography (EUS) : Report of Two Cases

Naoki KOMORI, Yoshikazu YAMAGUCHI, Hideaki MORI, Toshio MURAKI, Atsush ...

Article type: Article
1990 Volume 21 Issue 3 Pages 395-401
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.395

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We experienced two cases of leiomyosarcoma of the stomach with exogastric growth diagnosed by endoscopic ultrasonography (EUS). Case 1: 75-yar-old woman came to Kyorin hospital with the chief complaint of right flank pain, nausea and vomiting. Abdominal ultrasonography and abdominal CT scan suggested a solid tumor contacting with gastric wall. A elevated lesion was noted at the lesser curvature of the gastric body and antrum by gastrofiberscopy. Then EUS was done. Case 2: 49-year-old woman was refered to our hospital for further examination of the solid tumor under the left lobe of the liver, which was detected by abdominal ultrasonography at screening. A protruding lesion was noted at the lower gastric body by gastrofiberscopy. EUS revealed a submucosal tumor that grew out of the forth layer of the gastric wall in the both cases. Gastrectomy was performed. In the resected stomach, there existed an exogastrically growing submucosal tumor measuring 9×8×7 cm and 4×3.5×2.5cm in size, respectively. Histological examination showed leiomyosarcoma of the stomach in the both cases. EUS is most useful on the diagnosis of gastric submucosal tumor as it provides precise data about its site and nature, and it is able to discriminate between an extrinsic compression and an intraparietal lesion. But it is difficult to differentiate between benign and malignant tumors.

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Cranial Form of Guillain-Barre Syndrome Successfully Treated by the Pulse Therapy with Methylprednisolone

Minoru NOZAKI, Satoshi UCHIDA, Hidemi KOIKE, Yoshikazu YOSHINO

Article type: Article
1990 Volume 21 Issue 3 Pages 403-408
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.403

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We described a case with cranial form of Guillain-Barre syndrome (GBS), who was highly responsive to the pulse therapy such as the intravenous administration of methylprednisolone in high dose. A 57-year-old female was admitted because of diplopia and blepharoptosis. She has had a mild symptom of upper respiratory infection about 3 weeks before admission. Several days after admission, total ophthalmoplegia and bilateral peripheral facial nerve palsy developed rapidly. Deep tendon reflexes were lost, however, neither palsy nor ataxia were observed. The albumino-cytological dissociation in cerebrospinal fluid (CSF) was observed and anti-myelin-antibody was positive in serum and CSF. Her symptoms were resistant to conventional corticosteroid therapy consisting of oral administration of prednisolone (60 mg/day). We, therefore, applied the pulse therapy such as the methylprednisolone in high dose (1000mg/day for 3 days) in this case. Most of her symptoms, (total ophthalmoplegia, facial nerve palsy and areflexia) were recovered remarkably. At present, she is in good condition without any neurological sequelae. A cranial form of GBS, especially the type of total ophthalmoplegia without any palsy in extremities, is very rare in the literature. As the effect of steroid therapy for GBS is not established yet, much work will be necessary to evaluate the effect of pulse therapy for GBS.

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[title in Japanese]

[in Japanese]

Article type: Article
1990 Volume 21 Issue 3 Pages 409-412
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.409

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[title in Japanese]

[in Japanese]

Article type: Article
1990 Volume 21 Issue 3 Pages 412-413
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.412

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[title in Japanese]

[in Japanese]

Article type: Article
1990 Volume 21 Issue 3 Pages 414-415
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.414

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[title in Japanese]

Article type: Appendix
1990 Volume 21 Issue 3 Pages 416-417
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.416

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[title in Japanese]

Article type: Appendix
1990 Volume 21 Issue 3 Pages 418-
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.418_1

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[title in Japanese]

Article type: Appendix
1990 Volume 21 Issue 3 Pages 418-
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.418_2

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[title in Japanese]

Article type: Appendix
1990 Volume 21 Issue 3 Pages 418-
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.418_3

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[title in Japanese]

Article type: Appendix
1990 Volume 21 Issue 3 Pages App8-
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.App8

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[title in Japanese]

Article type: Appendix
1990 Volume 21 Issue 3 Pages App9-
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.App9

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[title in Japanese]

Article type: Appendix
1990 Volume 21 Issue 3 Pages App10-
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.App10

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[title in Japanese]

Article type: Cover
1990 Volume 21 Issue 3 Pages Cover11-
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.Cover11

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[title in Japanese]

Article type: Cover
1990 Volume 21 Issue 3 Pages Cover12-
Published: September 30, 1990
Released on J-STAGE: February 13, 2017

DOIhttps://doi.org/10.11434/kyorinmed.21.Cover12

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