JOURNAL OF THE KYORIN MEDICAL SOCIETY

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The accidental formation of a thrombus in the venous reservoir (VR) has been observed during the use of cardiopulmonary bypass. Thrombus formation is thought to be related to the condition of blood flow inside the VR. In this study, two types of venous blood flow in the VR (TR and MR) were examined. Microbubbles were allowed to flow into the VR, luminance values were measured from ultrasound echo images, and the rise time, at which venous blood flowed out of the filter, was evaluated.
For both VRs, the outflow start time became shorter as the flow rate increased, but the time difference between each level tended to be shorter for TR and longer for MR. In the lower part of the VR (10 - 70 mL), no statistically significant difference was observed between the TR: 13.6 ± 4.2 sec and the MR: 15.6 ± 6.5 sec (P = 0.051). However, in the upper part of the VR (100 - 600 mL), a TR:17.2 ± 6.7 sec and MR: 37.5 ± 11.6 sec were measured, with a statistically significant difference in outflow initiation time between them (P < 0.01).
This study revealed the flow state of the venous blood differed between the MR and the TR. Furthermore, we have concluded that understanding the flow in the VR would enhance safety.

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