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Volume 50, Issue 6
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Yoshiro MATSUI2001 Volume 50 Issue 6 Pages 349-366
Published: November 10, 2001
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSOsseointegrated implants have begun to be used not only in general practice in dentistry but also in various clinical situations in the maxillofacial region. The process has yielded three problems: the spread of application, new materials and diagnostic methods, and management for difficult situations. This paper presents basic data and clinical guidelines for new applications, it investigates the characteristics of the materials and the usefulness of a new diagnostic method, and it studies effective techniques for difficult cases.
The results obtained are as follows: 1. Investigations into the spreading application
1) The lateral and superior orbital rim have sufficient bone thickness and width for the implant body to be placed.
2) Osseointegrated implants, especially by the fixed bridge technique, are not recommended in the craniofacial bone and jaws of young children.
3) Implant placement into bone after/before irradiation must be performed in consideration of impaired osteogenesis, the decrease of trabecular bone, and the time interval between implantation and irradiation.
2. Investigations into materials and diagnostic methods
1) Hydroxyapatite-coated and titanium implants should be selected according to the characteristics of the materials.
2) A dental simulating soft may also be applicable in the craniofacial region.
3. Investigations into the management of difficult cases
1) Hyperbaric oxygen therapy (HBO), bone morphogenetic protein (BMP), and tissue engineering should be useful for improving the quality and increasing the quantity of bone where implants are placed.
2) Soft tissue around implants placed in the reconstructed area should be replaced with mucosal tissue.
The data obtained here should be useful for increasing the efficiency of osseointegrated implants, but further basic research is required in the future.View full abstractDownload PDF (10955K) -
Takashi YOSHII, Shinya MAGARA, Daisuke MIYAI, Hidetaka NISHIMURA, Eiji ...2001 Volume 50 Issue 6 Pages 367-370
Published: November 10, 2001
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe authors prepared a mouse tibial osteomyelitis model caused by Staphylococcus aureus, and the tumor necrosis factor-alpha (TNF-α) level in bone was measured over time, using ELISA, after administration of roxithromycin (RXM) at 5 mg/kg/day, to investigate the expression of TNF-α in osteomyelitis and the inhibitory effect of RXM on expression. The TNF-α levels were significantly higher in an infected group than in a control (non-infected) group on days 3 to 28 after infection. Although there was no significant difference in TNF-α levels between a group that received RXM administration and a group that did not received RXM by day 14 after RXM administration, the TNF-α levels were significantly lower for the administration group on or after day 21, indicating the inhibitory effect RXM had.View full abstractDownload PDF (686K) -
Report No.2 A Comparison between Responded and Non-responded CasesHiroshi IWABUCHI, Kimio UCHIYAMA, Soichiro ASANAMI, Yoichi TANAKA2001 Volume 50 Issue 6 Pages 371-376
Published: November 10, 2001
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSLong-term combined therapy of roxithromycin (RXM), pronase, and carbocisteine was given to patients with chronic odontogenic maxillary sinusitis.
The results were retrospectively compared between responded and non-responded cases, as follows. This therapy was continued over 3 months, and the result was evaluated by MRI or CT. As a result, 32 sinuses were evaluated as well-responded cases and 26 as poorly-responded cases. No difference was observed between the two groups concerning patient background, possible cause of maxillary sinusitis and its treatment, extent of the inflamed site, nasal findings, and the diseased state of the maxillary sinus. Further, no abnormal findings were observed either in the detected microorganisms and the histopathological picture of extract. However, thickened bone wall of the maxillary sinus was observed in 21.1% of the responders but as high as in 63.6% of the nonresponders, with a statistical significant difference between the two groups. It was thus suggested that the presence or absence of thickened bone wall may predict the effect of this combined therapy.View full abstractDownload PDF (1042K) -
Miki JOTOKU, Satoru SHINTANI, Manabu TAKARADA, Masasumi HUKUZUMI, Hiro ...2001 Volume 50 Issue 6 Pages 377-380
Published: November 10, 2001
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSQuincke's edema is a demarcated localized edema involving the deeper layers of the skin, including the subcutaneous tissue.
A retrospective chart review was performed on 43 patients (19 men, 29 women; mean age, 40.3 years) who were given a diagnosis of Quincke's edema at Ehime University School of Medicine from 1977 to 1999. The major clinical symptom was edema of the face. In four cases, the edema involved the facecoincident with some other location. In six of the 43 cases, the edema was induced in association with dental care. Twenty patients showed recurrent symptoms. Since Quincke's edema occurs suddenly and disappears after a short duration, it is difficult to make a definitive diagnosis. We reported the clinical details of Quincke's edema with special reference to its diagnosis and treatment.View full abstractDownload PDF (1167K)
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