All issues
Volume 36 (1987 - 198･･･
- Issue 6 Pages 1158-
- Issue 5 Pages 1013-
- Issue 4 Pages 923-
- Issue 3 Pages 188-
- Issue 2 Pages 61-
- Issue 1 Pages 1-
Volume 36, Issue 5
Displaying 1-15 of 15 articles from this issue
- |<
- <
- 1
- >
- >|
-
Masaya MATSUBARA, Hideaki NAKAGAWA, Yoshiharu OKUMURA, Yasutaka KURAMO ...1988 Volume 36 Issue 5 Pages 1013-1022
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSDuring the 1970's many cases of serious silicosis occurred among migrant workers doing tunnel construction.
We studied the prevalence of silicosis in the eastern part of Toyama prefecture. Questionnaires were sent to all male inhabitants aged 30 or over in the five selected areas. Eight hundred and eighty-five of respondents (41%) had worked as migrant workers. Of these, 580 men (66%) had worked on the job with exposure to dust such as tunnel construction. Of this number, 482 men were examined by chest roentgenography. Of the 482 migrant workers whose job exposed them to dust, 424 silicosis cases (88%) were found. These patients included 195 cases of category 1, 123 cases of category 2, 59 cases of category 3 and 47 cases of category 4 silicosis.
Most of the patients retired and returned to their home villages without having been given any diagnosis and medical care at their places of employment. The silicosis in 297 cases (70% of the total number of disease patients) was first detected in the course of our research.
Two thousand and seventy-seven of the respondents for questionnaire in 1977 and 1978 were followed-up until the end of 1983. For those who died, the causes and dates of death were confirmed by death certificates. The mean person-years of observation per a person was 5.9. The subjects were divided into three groups.
The mortality rate per 1, 000 person-years of migrant workers who had worked in jobs with exposure to dust was 22.3. The mortality rate was significantly higher than that of migrant workers who had not worked in jobs with exposure to dust (14.9) and those who were not migrant workers (9.1). Especially significance is the excess mortality rate of migrant workers whose jobs exposed them to dust in ages 40 to 69.
The mortality rates for pulmonary tuberculosis, pneumonia & bronchitis and pneumoconiosis among migrant workers whose jobs exposed them to dust were higher than those among non-migrant workers.View full abstractDownload PDF (1391K) -
Hitoshi YASUDA1988 Volume 36 Issue 5 Pages 1023-1029
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSGround water samples were taken from 8 wells at Kitaura area of Gogoshima in Matsuyama City. The sample water was collected every month from June 1978 to January 1979 and some anions contained in them were analyzed in order to examin the characteristics of the ground water.
The concentration of anions in this Island wells were higher 2.5-13 times than that of inland wells. The average concentration of Cl- is 23 ppm, and this shows that sea water did not permiate into it. The high concentrations of SO42-, NO-3-N, and NH+4-N may be caused by chemical manure and compost which are given to the tangerine orchard. 74% of samples analyzed showed the coexistence of NO-2-N and NH+4-N. In this area, the flow direction of under groundwater may be 5→1→2, 8→7→2 based on the analysis of concentration correlation matrix and -columner section.View full abstractDownload PDF (954K) -
Kiyoichi NODA, Masashi ITOH, Takiko SHINDO, Masato HAYASHI, Kenichi HO ...1988 Volume 36 Issue 5 Pages 1030-1039
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSCerebral stroke in rural areas is a very important disease both from medical and social aspects. Among strokes, infarction which occurs most frequently in elderly persons is liable to result from atherosclerosis. And for the development of atherosclerosis, essential hypertension is the most important predisposing factor. Other than hypertension, aging, diabetes mellitus, hyperlipemia, esp. low HDL/Tch ratio, increased hematocrit values, coronary insufficiency, cardiac failure, arythmia, esp. atrial fibrillation, are also accepted important risk factors. Affirmative of such findings, the authors are convinced of the fact that atrial fibrillation which is increasing recently is closely related to both cerebral thrombosis and embolism.
But, in regard to cerebral infarction no signifying or trigger factor, similar to very high blood pressure, that trigger cerebral hemorrhage, is clarified as yet. It is made clear in this connection that cardiac failure predisposed by hypertensive heart disease in old age, assisted by pathophysiological and other environmental conditions, is the important factor. The authors also studied the clinical predisposing parameters and preventive measures about strokes.View full abstractDownload PDF (1572K) -
Saburo MASHIMA1988 Volume 36 Issue 5 Pages 1040-1045
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSThe population with life insurance by the organization amounted about to 18 millions in 1985. The incidence of stroke death was 0.36‰ in 1984 and 0.35‰ in 1985. The latter figure was corrected to the national population to ae 0.92‰(national stroke death 1.12‰). Stroke mortality was strongly dependent on the age. Sex differences were larger at 40 to 60 years of age and approach to 1.0 in the group over 70 years of age. According to the description on the death certificate, which was available in 4, 147 cases, the incidence of cerebral bleeding was 41%, cerebral thrombosis or embolism 27% and subarachnoidal hemorrhage 19%. Thirty percent of cases died within 24 hours from the onset of attacks and 25% within 1 month. Early death was frequent in cerebral hemorrhage and in younger cases. Out of 4, 147 cases above, 1, 655 cases had medical examination at the entry. They showed lower mortality rate than the corresponding age group of those without madical examination. Cases with high blood pressure at the entry showed shorter survival period and higher incidence of cerebral hemorrhage.View full abstractDownload PDF (649K) -
From 1921 Autopsy Casses of Stroke in 20 YearsMasashi ITOH, Takiko SHINDO1988 Volume 36 Issue 5 Pages 1046-1050
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSPurpose: The number of autopsy cases at our department of internal medicine for 20 years from September 1966 reached 1, 921. The autopsy rate stood at 91%. Of them, cases with stroke accounted for 1, 119 (59%). Taking up cerebral infarction and cerebral hemorrhage, we studied changes in type and risk factors for cerebral infarction.
Findings Those subjected to autopsy for stroke included 565 persons with cerebral infarction, 396 with cerebral hemorrhage and 158 with subarachnoid hemorrhage, but those with myocardial infarction accounted for only 107 (5%). In recent years, there has been an increasingly high incidence among old people, In the age group of 70 and over, cerebral infarction accounts for 65-70%, myocardial infarction 61-68% and cerebral hemorrhage 43-49%.
When the period is divided into the first and second halves, and the patients into the age group of 60 and over and the younger group to check changes in the prevalence of cerebral infarction and cerebral hemorrhage, it follows that the prevalence of cerebral infarction has been higher that than of cerebral hemorrhage in recent years, because the incidence of cerebral infarction in the age group of 60 and over has increased.
When the changes are analyzed with cerebral infarction and small infarction, we learn that the increase in the number of cases with infarction is ascribable to a rise in that of cases with large infarction or cortical branches. A check of the relationship between large infarction, atrial fibrillation and valvular disease reveals that tce increase in the incidence of large infarction stems from the infarction of old people afflicted with atrial fibrillation. A check of the relationshdp between the infarction of old people and hypertension and cholesterol indicates that the infarction is closely tied in with hypertension in past history and less correlated to hypercholesteremia. There still are fewer cases with infarction correlated to hyperlipemia than in the Western countries. For its prevention, it is important to control hypertension.View full abstractDownload PDF (605K) -
Takiko SHINDO, Masashi ITOH1988 Volume 36 Issue 5 Pages 1051-1056
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSIt is well known that extraordinarily high levels of erythrocyte concentration in the blood as observed in plethoric patients are a warning signal for cerebral apoplexy.
With radical changes in the social environment, psychogenic stress and cigarette smoking have pushed the incidence of erythrocytosis upward.
In rural areas, where anemia has traditionally been a major health threat, the nutritional conditions have been improved dramatically. Situations are such that more attention should be directed toward plethora.
The rise in Ht reading means the rise in blood viscosity, which could trigger off cerebral infarction in elderly people suffering from arteriosclerois.
People whose Ht reading is constantly high have a very high risk of cerebral apoplexy. Our survey of the people aged 70 and above found that the incidence of cerebral apoplexy was 50% in the Ht. 49-51% group and 100% in the Ht. 52% and above. The aged are easily affected by hemoconcentration due to dehydration. So, the slightest rise in Ht levels could lead to cerebral apoplexy. With a view to preventing the disease, the authors propose, the Ht. level of the old people should be kept below 43%.View full abstractDownload PDF (458K) -
Masato HAYASHI, Ken-ichi HOSOYA1988 Volume 36 Issue 5 Pages 1057-1064
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSIt has been reported by many workers that the patients with atrial fibrillation have risk factors that give rise to cerebral infarction. Nonetheless, no report has been made on whether or not there can be a difference in the development of ischemic cerebrovascular disorders, depending on the actual condition at the onset of atrial fibrillation, particularly a varying degree of ventricular pause and heart rate, etc.
Investigations were made on 318 patients with continuous atrial fibrillation and 114 with paroximal atrial fibrillation in a total of 432 patients, ranging in age from 22 to 89 years in a ratio of 2: 1 between male and female with a mean of 65.1±11.2 years, who were included in the current study.
The results have proved to be worthwhile when ventricular pause was studied by Holter's ECG. When ischemic cerebrovascular disorders were observed at varying intervals longer than 2.5, 3 and 4 seconds, a significant difference was noted between the intervals longer than 2.5 and 4 seconds in the incidence of ischemic cerebrovascular disorders (p<0.05). Lone atrial fibrillation showed a similar tendency in this aspect, regardless of the presence or absence of basic diseases.
The duration of ventricular pause remained unchanged in the therapy combined with digitalis, but significantly extended when Ca-antagonist, and Beta-blocker were used. Thus, it may be important to be carafau in the selection of medications.View full abstractDownload PDF (1020K) -
Koji ISOMURA1988 Volume 36 Issue 5 Pages 1065-1071
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSConducted in the Saku district (pop: 105, 000) of Nagano Prefecture, a WHO collaborative study and a district survey on the onset of stroke (994 respondents), it is evident that the past history of hypertension was extremely significant both for patients with cerebral hemorrhage and cerebral thrombosis. Among patients with cerebral hemorrhage and those, 69 years old and under, with cerebral thrombosis, the group which undid or suspended hypertension treatment was evidently larger than that who continued to undergo treatment. But among those, 70 years old and over, with cerebral thrombosis, no significant statistical difference was noted between the two groups.
In Yachiho, a mountain village in the Saku district, hypertension control has been carried out since 1959. As a result of the adequate control of blood pressure, strokes as a whole have dropped by about 30% and cerebral hemorrhage has halved. But there are signs of an increase in the prevalence of cerebral infarction, and multiple cerebral infarction in particular, among the elderly.
In recent years, the Westernization of the dietary pattern has been in progress in rural communities, thereby raising the serum total cholesterol level among their residents. An epidemiological study of strokes in 1964-71 demonstrated minus correlations between serum total cholesterol and the incidence of cerebral thrombosis, but no such correlations are observed at present. Nor is any correlation observed between serum total cholesterol and cerebral infarction.View full abstractDownload PDF (959K) -
(2) Risk factors on long term cohort study, from 1965 to 1985Masami NOJIRI, Masataka NAKANO1988 Volume 36 Issue 5 Pages 1072-1078
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSA cohort study on risk factors for all strokes and heart diseases was conducted among residents of 30-69years old in Kamo, a farming and fishing village, Shizuoka Prefecture. A study cohort (588 men and 938 women) was assembled in 1965 and followed up to 1985, for about 20 years. All dropouts by deaths from all strokes and heart diseases were checked by death certificates during these periods. The mortality rate and relative risks of death from all strokes and heart diseases were calculated, especially of those aged 50-69. The major results obtained were as the followings.
1: The death rates of all strokes and heart diseases were higher in the advanced age (from 50 to 69 years) than in the middle age (from 30 to 49 years). Sex differences were not observable in statistically.
2: The analysis of the significant risk factors revealed that systolic and diastolic hypertension, hypertensive and sclerotic changes indicated by fundscopic findings, auricular fibrillations on e. c. g, . fatness, ex-smoker, ex-drinker and having no-occupation were important for all strokes.
For the death of heart diseases, systolic hypertension, alubuminuria, Q-waves, ST-T changes on e. c. g. and smoking less than 19 cigaretts daily were regarded as significant risk factors.View full abstractDownload PDF (818K) -
Yoshitaka SEKIGUCHI1988 Volume 36 Issue 5 Pages 1079-1084
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSRisk factors examined within one year before the onset of the attack were investigated in 92 cases with cerebrovascular accident.
Systolic and/or diastolic hypertension, hyperuricemia, elevated SUN and abnormal ECG findings (atrial fibrillation, T wave abnormality, QRS high voltage, abnormal Q wave) were related with CVA.
Also, CVA were frequently encountered with thinness, anemia, hypoproteinemia and hyperglycemia in male, and obesity, hypertriglyceridemia and elevated serum creatinine in female.
Hypertension, hyperglycemia, elevated SUN and serum creatinine played inportant roles in the occurrence of cerebral infarction, and hypertension and hypertriglyceridemia in cerebral hemorrhage.View full abstractDownload PDF (662K) -
Hideomi FUJIWARA1988 Volume 36 Issue 5 Pages 1085-1089
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSGenerally, valvular heart disease, pacemaker implantation and atrial fibrillation are considered to have some relationship to the onset of stroke, because of their tendency for intracardiac thrombus formation. But the factors which influence the stroke onset have not be clarified precisely. We examined underlying heart disease in patients with cerebral infarction whose clinical courses could be known clearly. Heart diseases were complicated in 11 cases of 25 patients with stroke. Tcese 11 cases consisted with myopathy (3 cases), valvular heart disesase (3 cases), pacemaker implantation (2 cases) and others (3 cases). In 14 cases with intracardiac thrombus, only 3 cases were revealed to become stroke. In 122 pacemaker implanted patients, 6 cases were died with stroke. Risk factors and genetic analysis of lipids were evaluated in both cerebral infarction and myocardial infarction. Although the rate of complication with hypertension was significantly higher in both cerebral infarction and myocardial infarction than in normal controls, the rate of complication with hyperlipidemia was lower in cerebral infarction. As the some specific genotypes of Apo-E were seen in myocardial infarction, they were never seen in cerebral infarction.View full abstractDownload PDF (555K) -
Hirohito SEKI1988 Volume 36 Issue 5 Pages 1090-1094
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSTo make sure whether Systolic Time Intervals (STI) is useful in predicting cerebrovascular disease earlier, an analysis of the main components by the Jacoby method were made on 120 men and women ranging in age from 17 to 80. Provided that valuables are age, systolic blood pressure (st), (et/ict) cardiac stroke volume (Kv), arteriolar pulse wave compliance (comp), systolic heart radius (scrad), faculty coefficient (fi), and heart rate (hr), the subjects could be divided into two-healthy group (first major component) and hypertensive/cardio-mulfunction group (second component). This fact shows that the use of STI is effective in analyizing the function of the heart and the blood vessel system. It also proved that cardiac stroke volume and arteriolar pulse wave compliance measured by STI decreased in the cases of hypertension in which afterload rises with the elapse of time and the cases of atrial fibrillation marked by disordered diastolic period due to irregular RR intervals. These conditions, if sustained long, could cause cerebral apoplexy to occur.
The cases of cerebral apoplexy were studied retrospectively. Six months before onset, arteriolar pulse wave compliance had decreased. Three months before onset, ICT and heart radius between beats had increased, while KV, ET/ICT and FI lowered. And one month before onset, systolic blood pressure rose.
From the foregoing, the lowering of arteriolar pulse wave compliance, heart contraction and cardiac output, and the increase in the heart radius in the systolic period are considered the major forebodings of cerebral apoplexy.View full abstractDownload PDF (641K) -
Kiyoichi NODA, Hiroto SEKI, Yoshiko OKADA, Tomotoshi OHNO1988 Volume 36 Issue 5 Pages 1095-1106
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSAging, hypertension and diabetes are the three major risk factors that predispose to atherosclerosis. The authors tried to elucidate the terminal clinical pictures of these three major factors in terms of the mechanocardiographical findings and blood chemistry parameters related to nutrition (NBC), which are considered to be useful for the determination of the signifying or trigger risk factors of impending cerebral attacks.
As the terminal clinical pictures of each of these three major factors, increase in peripheral resistance and inclination to low cardiac functions were observed. And in the process of transition to terminal pictures, increase in serum lipids and decrease in albumin, accordingly, increase in lipid/protein ratio were observed. Increase in such ratio is considered to be important for the development of atherosclerosis and low cardiac function.
In rural areas mortality rate of strokes is markedly higher than in urban areas. Such high stroke incidence may be ascribed to the marked increase in cardiac impairments, as compared with the urban hypertensives of the same age groups. The factor of cardiac impairments may be ascribable to different nutritional conditions.
Therefore, for the purpose of prevention against predisposition to strokes, early detection, as well as treatment, of cardiac impairments of elderly people, hypertensives and diabetics are deemed necessary. In this connection, improvement of nutritional conditions is very important.View full abstractDownload PDF (1397K) -
Hirohito SEKI, Hideomi FUJIWARA, Masashi ITOH, Takiko SHINDO, Masato H ...1988 Volume 36 Issue 5 Pages 1107-1113
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSCerebrovascular disease is still considered a serious health problem in Japanese rural areas. The rate of death from the disease is very high. Many clinical and epidemiological studies have been conducted so far. However, they have failed to come up with answers effective for prediction and prevention of the scourge.
As part of the agricultural coop commissioned research project entitled “Study of Cerebral Apoplexy: Its Prediction and Prevention, ” we took a questionnaire survey in 1985-86, to obtain data as regards patients' subjective symptoms, electrocardiographic observations, hematological findings and many others before the onset of cerebral apoplexy. Five medical research institutes affiliated with the national welfare federation of agricultural cooperatives responded to our questionnaire.
As a result, the subjective symptoms that showed stochastically significant increases from one year to three months before the onset of the disease as a whole were fatigue, forgetfulness and insomnia. When it comes to cerebrovascular infarction, shortness of breath, angina, forgetfulness, and nocturia were particularly notable.
All these symptoms are not peculiar to cerebral apoplexy, but it should be noted that these are the warning signals of the killer disease.View full abstractDownload PDF (773K) -
1988 Volume 36 Issue 5 Pages 1114-1131
Published: January 30, 1988
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSDownload PDF (2812K)
- |<
- <
- 1
- >
- >|