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Volume 48 (1999 - 200･･･
- Issue 6 Pages 790-
- Issue 5 Pages 695-
- Issue 4 Pages 583-
- Issue 3 Pages 202-
- Issue 2 Pages 83-
- Issue 1 Pages 1-
Volume 48, Issue 2
Displaying 1-11 of 11 articles from this issue
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Nobuyuki HORIUCHI, Shiho SEKI1999 Volume 48 Issue 2 Pages 83-95
Published: July 20, 1999
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSPesticide-related dermatitis has a high rate of incidence in rural communities, adversely affecting the health and livelihood of farmers. The important task we should take upon ourselves is to find out how to reduce exposure to agricultural chemicals directly injurious to the health of rural people.Especially, regarding those skin disorders characterized by chemical burns due to severe irritation or allergic contact dermatitis that develops as a result of sensitization reaction to chemicals, the mainstay of prevention is identification of allergens and substances causing skin disturbances and avoidance of exposure to them.
From this standpoint, we made clinical and epidemiological studies in a total of 380 patients who were treated for pesticide-related dermatitis at the Department of Dermatology of Saku Central Hospital, Nagano, during the period of 23 years from 1975 to 1997.
As a result, the following points were made clear as features of dermatitis associated with exposure to agricultural chemicals over the past 10 years:(1) The number of severe cases that require medical treatment has been on the decrease;(2) there has been a tendency to increase in the incidence of chemical burn type dermatitis by irritantagents such as Dazomet, Glyphosate and methyl bromide; and (3) the occurrence of chronic and solar type dermatitis has been declining.View full abstractDownload PDF (10852K) -
Gen KURAMOCHI, Kenji SHIMA, Isao KOBAYASHI1999 Volume 48 Issue 2 Pages 96-101
Published: July 20, 1999
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSIt has been known that access recirculation is positively related to dialyzer blood flow and is negatively related to access blood flow in the vascular access in hemodialysis patients. The present study was designed to examine whether an increase in access recirculation generated by an increase in dialyzer blood flow is related to access blood flow. All patients had native end-to-side arteriovenous anastomoses at the radial site. We measured access recirculation at two different dialyzer blood flow rates (85 and 170 ml/min) using a three-needle technique. Access blood flow rates (mean 668 ml/min ranging from 493 to 1038 ml/min) were measured using Doppler ultrasound sonography. We confirmed that an increase in dialyzer blood flow rate led to an increase in access recirculation (5.4±1.1 vs. 9.9±1.9%, p<0.05), and that access recirculation was negatively related to the access blood flow rate (y=-30.78x+972.20, r=-0.79, p<0.05). We further found a negative correlation between the increase in access recirculation generated by the increase in dialyzer blood flow rate and access blood flow rate (y=-33.88x+821.57, r=-0.75, p<0.05). These results suggested that dialyzer blood flow less affects access recirculation when access blood flow is higher.View full abstractDownload PDF (575K) -
Reality of Their Lives and Needs as Observed by MSWsMasayuki HATTORI1999 Volume 48 Issue 2 Pages 102-110
Published: July 20, 1999
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSCrohn's disease is an intractable bowel disease with inflammation. We studied the cases of 69 patients with Crohn's disease and dwelled on the needs of social as well as moral support of them.Of the total number of patients, 79.7% was males. The mean age was 27.5 years. As regards their living conditions, 45% lived together with their family, and 53.3% of those aged 25 to 35 years were single. Moreover, 33.3% was in unstable employment conditions.
Through counseling services, it was found that Crohn's disease patients and their families were badly in need of pensions and benefits like those for physically handicapped persons. These occupied high places on the list of their wishes together with the alleviation of psychological hardship, about which 24.6% of the patients complained.
Inflammatory bowel disease patients are in an extremely disadvantageous position. Plagued with the symptoms and dietary restrictions, they have difficulties in getting married and standing on their own feet, which calls for the need to further improve the welfare system for the handicapped. Their problems have somehow been dealt withby family members in many cases, but with a rise in the incidence of this disease and the aging of the population, we feel our urgent task is to establish a public support system for the intractable disease patients.View full abstractDownload PDF (972K) -
Yukihito MINATO, Shinkan YO, Koji HATTORI, Tatsuo SHIIGAI1999 Volume 48 Issue 2 Pages 111-115
Published: July 20, 1999
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSTranilast, an anti-allergic drug, was originally made in Japan, and is now being frequently used. Though ill effects of Tranilast in urology have been known widely, the adverse effect of Tranilast on liver function has been scarcely reported. Having experienced 7 cases of liver disease due to cholestasis by the drug, we summarized these cases and reported the characteristics of liver injury induced by the drug.
All the patients, who had took Tranilast orally and developed liver injury, first manifested hematuria and micturition pain, and then developed jaundice. Though the degree of liver injury was various depending on individuals, the clinical course turned better about 27 days after cessation of Tranilast.View full abstractDownload PDF (2515K) -
Iwao ISHI, Hajime KIMURA, Mimbu OOHATA, Setsuko SUZUKI, Tatsuo SHIIGAI ...1999 Volume 48 Issue 2 Pages 116-123
Published: July 20, 1999
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSThere is a theory that excessive treament for terminally ill patients is one of the factors in soaring medical costs. To evaluate this theory, we examined the changes in medical expenditures for our inpatients: 41 patients with lung cancer and 69 patients with liver cancer hospitalized for treatment of the department of internal medicine, and 90 patients with stomach cancer and 100 patients with colon cancer hospitalized for surgery from July to December 1997. They were divided to two groups: the patients of group A received active treatment, and the patients of group B received conservative treatment. We selected 10 people randomly from each group, and compared the changes in medical costs.
The cost was significantly low in group B compared with group A. We examined the change in the cost every 5 days. Until 6 days before leaving our hospital, the cost is high sugnificantly in group A compared with group B. The difference between group A and group B in the cost of treatment for lung cancer, and stomach cancer patients disappeared in 5 days before leaving hospital. The cost of treatment for lung and liver cancer patients of group A was a little higher than the average hospitalization fee of internal medicine. Also, the cost of group A stomach cancer patients was a little higher than the averge hospitalization fee of surgery, though there was no difference between the cost of treatment for group A colon cancer patients and the average hospitalization feeof surgery. The fee of group B of either disease was half or less of an average fee for medical treatment.
From this study, no evidence was found that the excessive life prolongation treatment for terminally ill patients was done. So, using authentic data, we should discuss the justifiability of the theory that the excessive treatment for terminally ill patients is one of the factors contributing to a boost in medical costs.View full abstractDownload PDF (951K) -
Shinji ASANUMA, Makoto USUDA, Mitsuru ANDO, Shosui MATSUSHIMA, Toshika ...1999 Volume 48 Issue 2 Pages 124-131
Published: July 20, 1999
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSA China-Japan joint project was carried out to study the incidence of fluorosis caused by coal burning in China from 1995 to 1997.
The health survey covered a control area and two flourosis areas. In those research areas, drinking water was not polluted with fluorides. The survey was designed to analyze the health status of people exposed to fluorides and evaluate the relationships between the dose and incidence of fluorosis. The concentration of airborne pollutants in both indoor and outdoor air was measured. The concentration of fluoride in the urine was analyzed and definite diagnoses for dental fluorosis and skeletal fluorosis were determined.
As a result, the incidence of coal burning fluorosis was confirmed in studied areas. Moreover, the fluorosis was caused not only by the direct inhalation of the airbone fluorides in indoor air but also by the intake of cereals polluted with fluorides. Fluoride was contained in both coal and soil. Therefore the mixture of coal and soil used for the adjustment of fire energy contributed to the air pollution to a great extent. The typical polluted crops were red pepper, corn and potato. An extremely high concentration of fluoride in the urine of residents in the polluted areas was detected.View full abstractDownload PDF (8057K) -
Akiko KONDOH, Kazuko ISHIZUKA, Gen KURAMOCHI1999 Volume 48 Issue 2 Pages 132-136
Published: July 20, 1999
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSIgA nephropathy is the commonest form of chronic glomerular disease. The clinical manifestation of this disorder suggests an association with upper respiratory tract infections. Recently it has been reported that Haemophilus parainfluenzae has a role in the etiology of IgA nephropathy. Therefore, the relationship between glomerular disease and oral bacterial flora has attracted attention. Also, it is demonstrated that H. parainfluenzae can bind to high-molecular weight salivary mucins in a selective manner in humans. The present study focused on the changes in salivary bacterial flora, particular H. parainfluenzae species, with the progress of glomerular disease in patients with chronic glomerulonephritis (CGN), and chronic renal failure (CRF), and patients receiving hemodialysis (HD). With the progress of glomerular disease, the prevalence of Micrococcus, H. parainfluenzae, and Bacillus decreased, and the prevalence of Candida and CNS increased. The decrease in the prevalence of H. parainfluenzae was most remarkable. Serum complement (C3, C4, and CH50) levels decreased significantly in CRF and HD patients compared with those in CGN patients. Serum IgA levels in patients with H. parainfluenzae did not differ significantly from those in patient without H. parainfluenzae in each stage of glomerular disease. In conclusion, salivary bacterial flora changes with the progress of glomerular disease. The overwhelming prevalence of H. parainfluenzae in the stage of CGN compared with the stages of CRF and HD, may support the hypothesis that H. parainfluenzae has a role in the etiology of chronic glomerulonephritis.View full abstractDownload PDF (568K) -
Mitsuya ONO, Hideaki FUJIWARA, Hiroaki KAWAJIRI, Yoshio NISHIGAKI1999 Volume 48 Issue 2 Pages 137-142
Published: July 20, 1999
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSThe numbers of cases of high level of serum lactate dehydrogenase (LDH) found in the mass screening program by Naganoken Koseiren Kenkokanri Center was 1, 358 (1.5% of total 89, 837 examinees) in 1995. In 235 of these cases, 141 cases (60.0%) were diagnosed as normal; 56 cases (23.8%), hyper lactate dehydrogenasenemia; 27 (11.5%), diseases of the liver or gallbladder. Close medical examinations including abdominal ultrasonography and check on viral hepatitis may be necessary for cases of increased LDH levels detected by mass screening.View full abstractDownload PDF (705K) -
Kenji SHIMA, Gen KURAMOCHI1999 Volume 48 Issue 2 Pages 143-148
Published: July 20, 1999
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSThis study focused on the local hemodynamic changes created by hemodialysis therapy in the forearm with arteriovenous fistulas for hemodialysis. Arteriovenous fistulas were created in the distal site of the forearm in all the patients who participated in this study. We measured the blood flow volume and blood flow rate in the arteriovenous fistulas using the Doppler ultrasonic flowmeter, and oxygen saturation using the pulse oxymeter and wave height using the plethysmogram in all the fingers of the forearm with arteriovenous fistulas as makers of local hemodynamics before and after hemodialysis therapy was given. After hemodialysis therapy, the patients' body weight reduced by an average of 2.5kg. Reduction of body weight (body fluids) led to decreases in mean blood pressure (99±4 vs. 80±5mmHg) and increases in heart rate (68±2 vs. 72±3 bpm) and hematocrit level (35±1vs. 38±1%) compared with those before hemodialysis. Furthermore, the reduction of body weight tended to decrease the blood flow volume and blood flow rate in arteriovenous fistulas. However, no significant changes were found in blood flow volume and blood flow rate in arteriovenous fistulas between before and after hemodialysis. We further studied the changes in oxygen saturation and wave height in all the fingers of the forearm with arteriovenous fistulas. No significant change was found in oxygen saturation between before and after hemodialysis. However, wave height tended to decrease after hemodialysis.These results suggest that the changes in body weight (body fluid), blood pressure, heart rate, and blood viscosity created by an usual hemodialysis therapy less affect the local hemodynamics in the forearm with arteriovenous fistulas.View full abstractDownload PDF (605K) -
Hideo TSURUSHIMA, Takao KAMEZAKI, Yasushi NAGATOMO1999 Volume 48 Issue 2 Pages 149-151
Published: July 20, 1999
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSWe report a case of a 17-year-old man with subarachnoid hemorrhage (SAH). SAH was from ruptured of an aneurysm of the left middle cerebral artery, for which the clipping was performed. After the surgery, vasospasm was observed by angiographyand the arterial injection of HCI-papaverine was done. A review of the literature is also made.View full abstractDownload PDF (3861K) -
Norifumi WADA, Yo YASUDA, Tadashi ARAI, Yuji ITO, Kazuyoshi HAYAKAWA, ...1999 Volume 48 Issue 2 Pages 152-155
Published: July 20, 1999
Released on J-STAGE: August 11, 2011
JOURNAL FREE ACCESSWith household digital compact wrist blood pressure monitors, blood pressure was measured in hemiplegic patients who were receiving kinesitherapy.
During the training program routinely worked out by physical therapists, most patients had shown elevated levels of both systolic and diastolic blood pressure. There were some patients whose blood pressure went up so high as to call doctors' attention.
As changes in blood pressure are affected by various factors, we cannot say at once that doing exercise alone adds to blood pressure. Nonetheless, by using a household blood pressure monitor, it would be easy to know the extent to which blood pressure rises in accordance with the amount of exercise, so that it would be possible to make patients and their family aware of the importance of blood pressure readings. We thought it possible to obtain an index of the amount of exercise at home.View full abstractDownload PDF (478K)
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