巻号一覧
11 巻, 1 号
選択された号の論文の8件中1～8を表示しています
- |<
- <
- 1
- >
- >|
-
竹市 雅俊1986 年 11 巻 1 号 p. 2-7
発行日: 1986/01/01
公開日: 2011/03/04
ジャーナル フリーSelective cell adhesion is thought to be a basic process of animal morphogenesis. In this article, I discuss the possible mechanism of selective adhesion of mammalian and chicken cells, fousing attention to a particular class of cell adhesion molecules termed cadherins. Cadherins play a major role in cell-cell connection in most kinds of vertebrate tissues, being devided into subclasses with different immunological and functional specificities. The subclasses so far identified were three types, E, N and P types. When tissue distribution of these cadherins in mouse and chicken embryos were determined by immuno-histochemical studies, we found that each type of cadherin displayed a unique distribution pattern. Embryos at the very early developmental stage expressed E type only, and during development they began to express other types. Onset of expression of N and P types was associated with various morphogenetic events. For example, in the process of neural tube formation, the neural plate and other parts of the ectoderm originally expressed E type. However, during invagination of the neural plate, this tissue ceased expression of E type but instead started expression of N type. We found other similar examples showing that switch in expression of cadherins from one type to another is associated with segregation of cell layers. These results suggested that cadherins may be a key factor for selective cell adhesions involved in morphogenetic processes.抄録全体を表示PDF形式でダウンロード (1053K) -
今西 幸男1986 年 11 巻 1 号 p. 8-21
発行日: 1986/01/01
公開日: 2011/03/04
ジャーナル フリーLife phenomena in which biological membranes are intrinsically involved in the acceptance and the transduction of stimulus and information, such as the cell adhesion, the action of noncholesteric hormones, the enhanced metabolism of glycophospholipids, and the immune reactions, are briefly reviewed. With these scientific progresses in mind, the interaction of lectins with cellular model system, which consists of lipid bilayer membranes containing synthetic fluorescent glycopeptides, was investigated. It was found that the lipid membrane not only acts as a medium for the interaction of glycopeptides, but also participates directly in the acceptance and the transduction of information. Finally, an approach to an artificial cell, which contains integral (structural) proteins, is discussed.抄録全体を表示PDF形式でダウンロード (1695K) -
下中 浩之, 山本 道雄1986 年 11 巻 1 号 p. 22-32
発行日: 1986/01/01
公開日: 2011/03/04
ジャーナル フリーMore than a century after the discovery of anesthesia, the biological mechanisms of anesthetics is still not fully understood. Enthusiasm among anesthesiologists for elucidating the mode of action of anesthetics appears to have receded in recent years, presumably because the method of study became more oriented toward basic sciences. Recently, it is generally accepted that an interaction between anesthetics and biological membranes may play a pivotal role in anesthetic action on biological tissues and organs. The most likely mechanism of anesthetic action involves synaptic membrane, and anesthetic molecules may block neural transmission by uncertain mechanisms including membrane perturbation of neuronal system. In this article, the recent concepts regarding the interaction between anesthetics and biological membranes are reviewed.抄録全体を表示PDF形式でダウンロード (1524K) -
吉岡 亨1986 年 11 巻 1 号 p. 33-40
発行日: 1986/01/01
公開日: 2011/03/04
ジャーナル フリーThe phototransduction mechanism of Drosophila retina was studied using visual transduction mutant, norp A. This mutant has no receptor potential, although it has normal content of rhodopsin and inferior morphorogy in visual cells. We compared protein phosphorylation and phospholipid phosphorylation including phosphatidylinositol (PI) turnover between normal and mutant eyes. Membrane phosphorylation experiment showed that phospholipid phosphorylation was greatly altrered in the visual transduction mutant, whereas no change was observed in the normal fly retina. In the mutant retina, the activity of DG kinase, which is known as phosphorylating diacylglycerol (DG) to phosphatidic acid (PA) was found to be reduced extremely. On the other hand, phosphorylation of cytosol protein was not changed between normal and mutant eyes.
We also found that PI specfic phospholipase C was absent, but activity of phospholipase A was not reduced in the mutant eyes. Gene dosage experiment revealed that DG kinase activity is parallel with rhabdomere size of Drosophila eye. Therefore, we can suggested that absence of PI specific phospholipase C is essential for the photoreceptor potential prodction.抄録全体を表示PDF形式でダウンロード (1145K) -
大矢 晴彦, 田中 佳典, 丹羽 雅裕, R ホングラダロム, 根岸 洋一, 松本 幹治1986 年 11 巻 1 号 p. 41-44
発行日: 1986/01/01
公開日: 2011/03/04
ジャーナル フリーPorous thin glass membranes of which thickness is in the range of 5 to 23μm have been prepared on the surface of porous ceramic tubing by coating with metal alkoxide solution, drying, heating and acid leaching sequentially. Structure of the membranes was investigated by Scanning Electron Microscope, and found that pore size is in the range of 4 to 64nm抄録全体を表示PDF形式でダウンロード (1150K) -
Takatoshi KINOSHITA, Masamichi SOTA, Yukio YADA, Akira TAKIZAWA, Yoshi ...1986 年 11 巻 1 号 p. 45-47
発行日: 1986/01/01
公開日: 2011/03/04
ジャーナル フリーPDF形式でダウンロード (373K) -
原谷 賢治, 小畑 健三郎, 白田 利勝, 吉留 浩1986 年 11 巻 1 号 p. 48-52
発行日: 1986/01/01
公開日: 2011/03/04
ジャーナル フリーThe permeability and apparent diffusivity calculated from time lag characterizing transport in a new type polyimide (PI) membrane have been measured for hydrogen, hellium, argon, oxygen, nitrogen, carbon monoxide, carbon dioxide, methane, ethane and propane. The apparent activation energies for permeation and diffusion have been also determined. The diffusivities were correlated with mean diameter of permeate gas molecules. The possibility of PI for gas separation membrane was discussed shortly.抄録全体を表示PDF形式でダウンロード (447K) -
橋田 勲, 勝水 淳, 西村 正人1986 年 11 巻 1 号 p. 53-57
発行日: 1986/01/01
公開日: 2011/03/04
ジャーナル フリーCellulose triacetate ultrafiltration membranes were prepared using the casting solution consisted of formic acid, additives, and polymer. Effects of additives in casting solution on membrane performance was studied. The addition of water and inorganic salts in casting solution rendered to increase in water-permeability, but to decrease in solute retention. On the other hand, the solute retention of membrane was improved by using a solvent containing dichloromethane. Membrane separation performance were examined for various solutes, such as sacchrose, amino acid, and organic acids with low molecular weight. Saccharose and amino acids were well retained by cellulose triacetate membrane, but retention levels of membrane for organic acids and tetraethylene glycol were very poor. The retention of aromatic amino acids, such as DL-tyrosine and L-phenylalanine were less in comparision to the data of aliphatic amino acids抄録全体を表示PDF形式でダウンロード (593K)
- |<
- <
- 1
- >
- >|