The infections in the oral cavity have been extensively observed in patients with the paradontitis including dental caries. Most of them are infected with the normal flora of the mouth. Disruption of the ecological balance of normal flora is a great factor leading to endogenic infections, and in these cases anaerobic bacteria play a big role. As anaerobic bacteria inhibit the oral cavity as part of the normal flora, they are very likely to be involved in suppurative inflammation in the oral surgery section. In the present study, anaerobic bacteria which were isolated from various cases of oral cavity infection over past decades were analyzed.
One thousand five hundred sixty cases of suppurative disease in the oral cavity were examined. The detection rate of bacteria alone was 95.5%. The rates of infection caused by anaerobic bacteria were 24.9% and 26.7% for gingival abscess and jaw bone osteomyelitis respectively, which were commonly observed in patients in the oral surgery section. In secondary infections of oral cancer, the rate of infection caused by anaerobic bacteria alone was 43.1%, indicating a very high detection rate. The rate of mixed infections caused by both anaerobic and aerobic bacteria in gingival abscess, infectious root canal, paradontitis, odontogenic sinuitis, and jaw bone osteomyelitis was more than 50%, indicating a high rate. In secondary infections for dental inflammation of the maxillary sinus and paradontitis, the rate of mixed infections were 69.7% and 71.7%, showing extremely high rate. Regarding various other inflammatory diseases, besides these infections caused by anaerobic bacteria alone, mixed infections were observed to be caused by several up to 8 kinds of bacteria. For example some of the gingival abscesses and the paradontitis were caused by 8 kinds of bacteria. Anaerobic bacteria were involved in almost all of the mixed infections as well as in many single infections. In the above mixed and single infections,
Streptococcus sp.,
Staphylococcus sp., and
Corynebacterium sp, were detected as predominant pathogenic aerobic bacteria, and
Veillonella sp. as the predominant pathogenic bacteria.
Bacteroides sp.,
Peptococcus sp. and
Fusobacterium sp, were extensively found as pathogenic anaerobic bacteria followed by
Veillonella sp.
CER showed a broad spectrum of antibacterial activity against gram-positive and gramnegative, aerobic, and anaerobic bacteria.
Since anaerobic bacteria are often to be responsible for the infections in the oral cavity area, the normal oral cavity flora have to be taken into consideration when treating oral cavity infections.
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