Relating to the general conception that sodium chloride plays an important part in the survival of totally adrenalectomized animal, the author conducted a series of experiment concerning the possible influences of sodium chloride administration to the adrenalectomized white rats upon the gustatory threshold and the plasma chloride concentration. The same gustatory threshold experiments were performed on the adrenalectomized white rats to examine the effect of Cortisone acetate administration. The results obtained are summarized as follows. 1. Plasma chloride concentration showed a decrease of about 6% after adrenalectomy. The animals became thirsty for the salt solution. When examined by the preference method, they developed as keen susceptibility for the salt solution that they could detect about twenty five times diluted salt solution as did the normal animal. 2. Although the total elimination of adrenal eventually proved fatal to the animal, administration of salt solution increased their survival period, presumably due in one part to compensating function of accessory adrenal developed during the certain time interval after the operation. 3. Gustatory threshold change to the salt solution after adrenalectomy did not suffer any appreciable fluctuation by the administration of Cortisone acetate.

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The time of erution of permanent teeth was investigated on youngsters raised up under the unfavorable dietary conditions during and directly after the Second World War. Totally ten thousand and two hundred thirty three primary and middle school children from six to fifteen of age were selected as the subjects, from Kokura city, suburban area of the same city, Yame region of Fukuoka Prefecture, Kumamoto city, region of Mt. Aso and Kitamorogata of Miyazaki Prefecture. The results are as follows. 1) The War effected delaying the time of eruption of permanent teeth. In the urban districts it was more slowed than in the provinces. 2) The earliest of the time is in Yame region, followed by Kitamorogata region, Kokura city, Kumamoto city, the suburban area of Kokura city, and the latest is in Mt. Aso region. 3) The delaying is more distinct in female than in male member. 4) Between the corresponding teeth of upper and lower jaws, the eruption is earlier in those of lower jaw than in upper, and earlier in female than in male for each tooth. 5) The order of eruption of each tooth in upper jaw is as follows. First molar is the first, followed by central incisor, lateral incisor, first premolar, cuspid, second premolar, and second molar is the last. In lower jaw the order first premolar and cuspid is reversed and others are the same. 6) The average time for eruption of each tooth is respectively 7.4 years for central incisor, 8.6 years for lateral incisor, 10.8 years for cuspid, 10.8 years for first premolar, 11.7 years for second premolar, 6.4 years for first molar, 12.5 years for second molar in upper jaw, and in lower jaw 6.6 years for central incisor, 7.5 years for lateral incisor, 10.4 years for cuspid, 10.6 years for first premolar, 9.2 years for first molar, 12.0 years for second molar.

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On the same subjects dealt in the foregoing chapter (ChapterI), the time of fall of deciduous teeth was investigated. The results are following. 1. The earliest of the time in male subjects is in Yame region, followed by the suburban area of Kokura city, Kokura city, Kumamoto city, Kita morogata region of Miyazaki prefecture and Mt. Aso region. In female subjects the earliest is in Kumamoto city, and Kitamorogata region, Kokura city, Yame region and the suburban area of Kokura city following it, Mt. Aso region is the latest. 2. The shedding of deciduous teeth is later in upper jaw than in lower jaw, and in female faster than in male. 3. Shedding of deciduous teeth is retarded by the deteriorated nutrition and the phenomenon is more clearlv noted in the suburban districts. 4. The shedding time of each deciduous tooth is as follows. Upper jaw : 7.4 years for central incisor, 8.4 years for lateral incisor, 10.7 for cuspid, 10.5 years for premolar, 11.6 years for molar. Lower jaw ; 6.6 years for centrel incisor, 7.6 years for lateral incisor, 10.0 years for cuspid, 9.7 years for premolar, 11.0 years for molar.

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Caries rate of primary and middle school children born and raised during the War period under the severe dietary conditions was investinted on the same subjects of the first chapter. The results are summarized as follows. A. Caries rate of deciduous teeth. 1. With increasing age of the children, the rate decreases in every district groop investigated. 2. Comparing between both sexes it is noted in every district groop that the caries rate is higher in female than in male until they reach eleven years of age and after twelve years of age the relation is reversed so that the rate is higher in male than in female. 3. Provincially the rate is higher in the order : Kokura city, suburban area of the same city, Yame region, Kitamorogata region, Kumamoto City and MT. Aso region. B. Caries rate of permanent teeth. 1. The rate is higher with increasing age. 2. The rate is highest in Kokura City, decreasing gradually in the suburbun area of the same city, Kumamoto city, Kitamorogata region and MT. Aso region is the lowest. C. Caries rate of deciduous plus permanent teeth. 1. In every districts the rate has a peak at eight to ten years of age, then it lowers toward twelve years of age and after then it rises steadily with increasing years. 2. It seems that eight to ten years mark is the critical period for youngsters' oral hygiene. 3. Caries rate seems to be regaining its prewar state.

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601 tuberculous patients admitted in the National Hospital of Fukuoka were examined in relation to the incidence rate of periodontosis. The results obtained were analysed statistically by the x^2 method and presented as follows. 1 Correlation may exist between the stages of the disease and the incidence rate of periodontosis. 2 Correlation may exist between the stages of both diseases. 3 Correlation may not exist between the year period elapsed from the incipience of tuberculosis and the incidence rate of paradontosis. 4 Correlation, however, may exist between the year period from the incipience of tuberculosis and the stages of paradontosis. 5 Correlation may not exist between the sex difference and the incidence rate of the paradontosis. 6 Correlation may not exist also between the sex difference and the stages of paradontosis. 7 Correlation may exist between the ages of tuberculous patients and the incidence rate of paradontosis.

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With an aim to know the possible influences of hot spring upon the physique, the eruption time of permanent teeth, the shedding time of deciduous teeth, the eruption of permanent teeth and decaying tooth number, 1914 school children residing in Beppu hot spring region and 929 school children of Toyooka-machi, neibouring town with similar living environment, were investigated. 1. The shedding time of deciduous teeth of school children living in the hot spring region is earlier than that of the children living in the nearby region lacking hot spring. 2. The shedding time of deciduous teeth of girl is earlier than that of the boy. 3. The order of shedding of each deciduous tooth reported here in this paper stands in fairly good agreement with those reported by other investigaters.

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