JOURNAL OF THE KYORIN MEDICAL SOCIETY

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The RapidPoint 400 (RP400) is a cartridge-type maintenance-free bio-safe gas analyzer. A single multi-use measurement cartridge contains all of the components of a traditional laboratory analyzer. We compared the values obtained from the RapidPoint 400 to those obtained from the traditional laboratory whole blood analyzer system (ABL625). A reference blood gas sample was obtained using bubble tonometry. The standard blood serum, SRM956a, was used as an electrolyte reference sample. Patient's blood samples (n=270) were also used for whole blood analysis. These three specimens were simultaneously measured by both machines to validate the results from the RP400. Both machines provided similar PO_2 values for both the tonometry and the patient blood samples. The RP400 provided a higher PCO_2 value for the tonometry sample, while providing a lower value for patient's blood samples. The serum value for Na and K was precisely measured by both the RP400 and ABL625, while the serum value of C1 was slightly underestimated by the ABL625, and overestimated by the RP400. Overall, the values provided by the RP400 were satisfactory when compared to those of the ABL625. The RP400 is a bio-safe and maintenance-free whole blood gas analyzer, which can be used for clinical use.

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It is possible to enforce medical treatment efficiently to the suitable case for an early stage, if the poor prognosis group which is likely to carry out lymph node metastasis of a biopsy can be sorted out. In this study, the expression of VEGF-C which was related to lymphangiogenesis was examined on VEGF-C expression and lymphatic vessel invasion in the breast cancer tissues. As the result, the breast carcinoma cell of the VEGF-C positive expression was confirmed in many lymphatic vessel invasion example, and the significant differential was between VEGF-C expression and lymphatic vessel invasion (p<0.001). It was suggested that VEGF-C in which the breast cancer tissues was produced became an useful factor which can predict the lymph node metastasis from the case without lymphatic vessel invasion and lymph node metastasis.

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The conventional operation to repair distal arch aneurysms via left thoracotomy is still associated with respiratory complications such as pulmonary damage and the need for prolonged ventilatory support. However, we believe that surgical repair of such an aneurysm either via the aortic arch with a stent-graft or by trans-femoral endovascular stent-grafting is preferable, being less invasive than the left thoracotomy approach, and is likely to result in less morbidity and mortality. In this study, we report the use of these two procedures, each in one case. One patient, with an aortopulmonary fistula, was treated by surgical repair through the aortic arch with a stent-graft, and the other, who had previously undergone Bentall's procedure, and who had a distal arch aneurysm, by trans-femoral endovascular stent-grafting. Both methods proved effective in the selected cases; and, even though trans-femoral endovascular stent-grafting is not entirely free of problems, its less invasive nature is expected to result in its more common use.

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