81 malignant tumor cases of the oral and maxillofacial regions were clinicostatistically observed at the Department of Oral Surgery at Dokkyo University Hospital from 1977 to 1988.
From this study, we obtained the following conclusions:
1) Of the 81 patients, 51 were male and 30 were female (1.7: 1), The patients ranged in age from 30 to 96 years, and the mean age was 65.4 yeacs.
2) The primary tumors sited on the gingiva in 35 cases (43.2%), tongue 14 cases (17.3%), oral floor 9 cases (11.1%), buccal mucosa 7 cases (8.6%), maxillary sinus 6 cases (7.4%), hard palate 5 cases (6.2%), lip 4 cases (4.9 %), submaxillary 1 case (1.2%).
3) Histopatopathologically, 67 cases (82.7%) were diagnosed as squamous cell carcinoma, 7cases (8.6%) as malignant tumors in the salivary gland, 2 cases (2.5%) as malignantlymphoma, 1 case (1.2%) as malignant melanoma and so on.
4) According to the TNM classification (UICC 1978, JJC 1977), 77 cases of oral squamous cell carcinomas involving lip and maxillary sinus were classified as 13 cases (16.9%) of T1, 27 cases (35.1%) of T2, 22 cases (28.6%) of T3, 15 cases (19.5%) of T4. In the NM classification, cervical lymph nodal metastasis was found in 32 cases (41.6 %) and 3 cases (3.9 %) had distant metastasis to the lung. In stage grouping, 11 cases (14.3 %) were in stage I, 18 cases (23.4%) in II, 26 cases (33.8%) in Ill, 22 cases (28.6 %) in IV.
5) 21 cases (25.9%) were treated by irradiation (R) alone, 17 cases (21.0 %) by surgery (S) +chemotherapy (C) + (R), 16 cases (19.8%) by (S+R), 11 cases (13.6%) by (C + R), surgery alone, 3 cases (3.7%) by chemotherapy alone and 2 cases (2.5%) by (S+C).
6) The 5-year survial rate was 43.0%, and tumors (22 primary lesions, 3 cervical metastases and 8 remote metastases) and other diseases were responsible for 11 deaths.
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