Neurologia medico-chirurgica
Online ISSN : 1349-8029
Print ISSN : 0470-8105
ISSN-L : 0470-8105
25 巻, 1 号
選択された号の論文の12件中1~12を表示しています
  • Kenichiro HIGASHI, Sanao KATAYAMA
    1985 年 25 巻 1 号 p. 1-8
    発行日: 1985年
    公開日: 2006/09/21
    ジャーナル フリー
    Changes in the cerebrospinal fluid (CSF) formation rate (Vf) with hypercapnia and papaverine infusion were measured by the ventriculocisternal perfusion technique in anesthetized dogs. In addition, local blood flow in the choroid plexus and cerebral cortex was measured by the hydrogen clearance method. When PaCO2 increased with 10% CO2 inhalation, Vf increased transiently and gradually decreased to the control level within an hour. This transient increase in Vf is considered to be due to mobilizing unequilibrated pools of CSF, caused by sudden changes of the craniospinal blood volume. Excluding such an apparent increase caused by an artifact, neither hypercapnia nor papaverine affected Vf.
    Local blood flow of the choroid plexus of 12 normal dogs was 72.8±13.1 ml100 gmin in average which was higher than that of the cerebral cortex; 57.8±12.4 ml 100 gmin. Although cortical blood flow increased to 225% of the control under hypercapnia with 10% CO2 inhalation, the choroid plexus blood flow did not increase significantly. Papaverine infusion also raised the cortical blood flow up to 143% of the control, while the choroid plexus blood flow did not increase significantly. From the above results, the choroid plexus, a major source of CSF, is demonstrated to be less reactive to vasodilatation induced by either hypercapnia or a vasoactive agent. This phenomenon favorably explanes, at least partially, the unchanged Vf under the effect of hypercapnia or papaverine.
  • Tomokatsu HORI, Hideharu NUMATA, Yasuo HOKAMA, Kiyoaki MURAOKA, Yoshik ...
    1985 年 25 巻 1 号 p. 9-14
    発行日: 1985年
    公開日: 2006/09/21
    ジャーナル フリー
    Estrogen-induced rat prolactinomas were produced after seven weekly injections of 2.5 mg of estradiol valerate. The rats were treated with various combinations of therapeutic agents. They were divided into four groups including the bromocriptine (CB) treated group, irradiated group, combined CB and radiation treated group, and finally the control group. Serum concentrations of prolactin and weights of tumors containing pituitary tissues were measured and statistically compared.
    The suppressing effect of CB against prolactinomas was well demonstrated in their hormonal activities. But it alone was not effective in reducing the size of prolactinomas. Concerning irradiation, on the 17th day it alone was not effective in reducing hormonal activities of rat prolactinomas. In the chronic stage, on the 30th day radiation alone was effective in reducing hormonal activity. Throughout the experiment CB was more potent than radiation in reducing hormonal activity. Concerning the size reducing effect, combined use of CB with radiation was significantly effective. If CB is not sufficient in reducing the size and hormonal activity of human prolactinoma, its combined use with radiation may be suggested.
  • Noboru GOTO, Mitsuo KANEKO, Keisei TANAKA
    1985 年 25 巻 1 号 p. 15-22
    発行日: 1985年
    公開日: 2006/09/21
    ジャーナル フリー
    Chronological and volumetric changes of the brain were studied with the help of an electronic optical planimeter in five autopsies from patients with left-sided embolism extending from the distal internal carotid artery to the proximal middle cerebral artery. Four brains had hemorrhagic infarctions. The survival periods were 2, 3, 4 and 11 days after the stroke. Characteristic diphasic abnormalities indicative of ischemic cerebral edema were noticeable not only in the ischemic hemisphere—especially when compared with the non-diseased side—but also in the non-ischemic hemisphere (although they were milder and started later in the latter case). The fifth non-hemorrhagic brain had only ischemic cerebral edema. There were no corticomedullary differences in volume between hemispheres. The patient survived two days.
    The concept of corticomedullary volume ratio was introduced to evaluate quantitative gradings of ischemic volume changes between the cerebral cortex and white matter.
  • Toru HAYAKAWA, Yoshikazu IWATA, Kazuo YAMADA, Norio ARITA, Shintaro MO ...
    1985 年 25 巻 1 号 p. 23-26
    発行日: 1985年
    公開日: 2006/09/21
    ジャーナル フリー
    We report a 31-year-old woman with an intracavernous carotid aneurysm who experienced a cerebral embolic complication during the gradual occlusion of an internal carotid artery (ICA) following superficial temporal to middle cerebral artery anastomosis. The cerebral angiogram revealed an embolus lodged in the stem of the middle cerebral artery. Based on our findings we suggest that in the presence of a sufficient collateral blood supply after extra and intracranial bypass surgery, abrupt ICA ligation may reduce the risk for thrombo-embolic complications. If, on the other hand, the collateral blood flow is insufficient, gradual ICA occlusion should be considered and anticoagulant therapy should be used.
  • Masakazu TAKAYASU, Akira SHINTANI, Makoto NEGORO, Takahiko ASAI
    1985 年 25 巻 1 号 p. 27-31
    発行日: 1985年
    公開日: 2006/09/21
    ジャーナル フリー
    Plain and contrast-enhanced computed tomography (CE-CT) was evaluated in 48 patients with 55 angiographically confirmed cerebral aneurysms by a method simulating the prospective study to show the real value. The detection rate by CE-CT was 44%. The CE-CT was a helpful diagnostic method, when there was no localizing sign in plain CT. Seven aneurysms out of fifteen (47%) without subarachnoid hemorrhage or other lacalizing signs in plain CT were detected by CE-CT. The CE-CT gave a more specific diagnosis and may be useful, when angiography is deferred. Though other less invasive techniques, like intravenous digital subtraction angiography, provides an alternative method at present, the detection rate of this study would represent one of the standards of less invasive tech niques for the diagnosis of intracranial aneurysms.
  • Shiro KOBAYASHI, Shozo NAKAZAWA, Masami YANO, Toshibumi OTSUKA
    1985 年 25 巻 1 号 p. 32-35
    発行日: 1985年
    公開日: 2006/09/21
    ジャーナル フリー
    Two patients are reported who showed evident extravasation of contrast medium into a blood clot in an intraventricular hemorrhage during contrast-enhanced computerized tomography. Both patients had a poor prognosis despite ventricular drainage. The findings may suggest an association with severe brain damage.
  • —A Case Report with Ultrastructural Study—
    Toshihiko KUBOTA, Shinjiro YAMAMOTO, Asoa HIRANO, Hideaki MURATA
    1985 年 25 巻 1 号 p. 36-41
    発行日: 1985年
    公開日: 2006/09/21
    ジャーナル フリー
    A rare case of primary low grade chondrosarcoma in the optic canal is presented. The fine structure of the tumor is generally that of a differentiated cartilage. The neoplastic cell cytoplasm has abundant glycogen granules, rough endoplasmic reticuli, Golgi apparatus and mitochondria. In the Golgi zone, secretory vacuoles frequently contain fine dense particles, associated with fine filamentous material, resembling the reticulated structure of extracellullar proteoglycans. Abundant mitochondria exist in the degenerated cells. Membrane invested matrix vesicles are frequently encountered in the amorphous material of disintegrated cells and in the vicinity of necrotic cells. Some of them may represent remnants of mitochondria. Intact neoplastic cells may secrete proteoglycans to make the chondroid matrix, while the degenerated tumor cells provide extracellular matrix vesicles for initial calcification.
  • Jun-ichi KURATSU, Yasuhiko MATSUKADO, Nobuhito NONAKA, Yoichi ITOYAMA, ...
    1985 年 25 巻 1 号 p. 42-44
    発行日: 1985年
    公開日: 2006/09/21
    ジャーナル フリー
    A case of cerebral toxoplasmosis in a 57-year-old female is reported, considered to be an acquired form of the disease, although no obvious immunosuppressive illness preceded the history. Clinical findings showed other interesting features with this patient, who developed convulsive disorders and had calcified round lesions in the basal ganglia and cerebral hemisphere. Toxoplasmosis antibody test was strongly positive and histological examination revealed intracellular protozoan toxoplasma.
  • —Case Report—
    Masamichi SHINONAGA, Gakuji GONDO, Kazuhiko FUJITSU, Takeo KUWABARA
    1985 年 25 巻 1 号 p. 45-49
    発行日: 1985年
    公開日: 2006/09/21
    ジャーナル フリー
    A rare case of Paget's disease of bone accompanied by osteogenic sarcoma which invaded into the intracranial cavity is reported. A 60-year-old woman was admitted complaining of disturbed consciousness, aphasia, right hemiparesis, and severe intermittent headaches. Skull X-ray films showed thick calvaria with “cotton wool appearance.” A CT scan revealed an intracranial enhanced mass lesion in the left occipital area. Elevated serum alkaline phosphatase was noted. Biopsy of the left occipital bone demonstrated osteogenic sarcoma complicating Paget's disease of bone. The tumor grew progressively, showing no response to irradiation, and the patient died. Paget's sarcoma is rare in Japan, where only one case of intracranial Paget's sarcoma has previously been reported.
  • —Case Report—
    Hiromi SATO, Noriko SATO, Mineo GAKIYA, Chin-Ying LO, Norihiko TAMAKI, ...
    1985 年 25 巻 1 号 p. 50-54
    発行日: 1985年
    公開日: 2006/09/21
    ジャーナル フリー
    Congenital teratoma of the orbit is a rare tumor, which usually manifests unilateral proptosis in an otherwise normal newborn infant. It rarely extends intracranially. A rare case of congenital orbital teratoma with intracranial extension, which presented microphthalmia from birth, is reported. Intracranial approach with orbital unroofing enabled total removal of this rare tumor during the neonatal period through combined efforts of neurosurgery and ophthalmology.
  • —Report of Two Cases and Review of the Literature in Japan—
    Jun SHINODA, Tomohiko IWAI, Toshihiro MORITA, Yoshiaki MIWA, Mitsuaki ...
    1985 年 25 巻 1 号 p. 55-60
    発行日: 1985年
    公開日: 2006/09/21
    ジャーナル フリー
    Two cases with traumatic arteriovenous fistula (AVF) arising from the superficial temporal vessels are reported. In both cases, AVF was diagnosed by angiography and then, removed totally with feeding arteries and draining veins. The postoperative course of both cases was uneventful and the preoperative symptoms disappeared.
    Traumatic AVF of the scalp is rare, and only 18 cases have previously been reported in Japan. Out of the total of 20 reported cases with AVF of the scalp, including our two cases, the authors are presenting a review of their sexes, ages, locations, symptoms, diagnoses, and treatments.
  • Tatsuya KOBAYASHI, Jun YOSHIDA, Naoki KAGEYAMA, Osamu MORI, Masamichi ...
    1985 年 25 巻 1 号 p. 61-65
    発行日: 1985年
    公開日: 2006/09/21
    ジャーナル フリー
    A case of successful treatment of child craniopharyngioma is reported. The tumor was totally removed seven years ago and the patient's height became normalized by human growth hormone (HGH) therapy lasting for 2 12 years. Completed development of his sexual characteristics and induction of spermatogenesis resulted from a combination therapy with human chorionic gonadotropin (HCG) and human menopausal gonadotropin (HMG).
feedback
Top