巻号一覧
33 巻, 6 号
選択された号の論文の10件中1～10を表示しています
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Shuji NIIKAWA, Akira HARA, Shinichi SHIRAKAMI, Wei ZHANG, Noboru SAKAI ...1993 年 33 巻 6 号 p. 345-349
発行日: 1993年
公開日: 2006/06/20
ジャーナル フリーHistochemical staining using lectins from Ricinus communis (RCA-1), Arachis hypogaea, and Canavalia ensiformis was investigated in 40 human gliomas, three central neurocytomas, one human neuroblastoma cell line (IMR-32), and two normal brain tissues. Staining was uniform in low-grade gliomas, but heterogeneous in high-grade gliomas, particularly with RCA-1. The correlation between RCA-1 reactivity and cellular proliferative potential was investigated in 10 high-grade gliomas using a combined staining technique: the silver colloid method for nucleolar organizer regions (Ag-NORs) and histochemistry with RCA-l. The mean number of Ag-NORs counted on a simple preparation was significantly greater in the nuclei of RCA-1-negative cells than in those of RCA-1-positive cells (p < 0.001). The staining intensity of inflammatory cells was obviously higher than that of neoplastic cells, and therefore inflammatory cells were easily discriminated from neoplastic cells. Combined RCA-1 histochemical and Ag-NOR silver colloid staining revealed heterogeneous expression of RCA-1 receptor in high-grade gliomas with changes in Ag-NOR number. This result seems to show that high-grade gliomas express heterogeneous cellular carbohydrate structure and proliferative potential even within the same tumor.抄録全体を表示PDF形式でダウンロード (514K) -
Yoshimasa KINOSHITA, Hidehiko KAJIWARA, Akira YOKOTA, Yosuke KOGA1993 年 33 巻 6 号 p. 350-359
発行日: 1993年
公開日: 2006/06/20
ジャーナル フリーWater-soluble metabolites extracted from 20 astrocytic tumors (11 glioblastomas, 3 anaplastic astrocytomas, and 6 low-grade astrocytomas) and four normal brains were measured qualitatively and quantitatively using in vitro high-resolution proton magnetic resonance (1H-MR) spectroscopy. MR spectra from tumors exhibited characteristic patterns according to malignancy, presumably reflecting the metabolism of gliomas. Concentrations of choline-containing compounds, inositol, alanine, and glycine increased according to the malignancy, while that of total creatine decreased. In particular, glycine concentration was very high in glioblastoma, and an immunohistochemical study using antiglycine antibody demonstrated that glycine was mainly distributed in glioma cells, not in proliferative endothelial cells. The ratios of choline-containing compounds and glycine to total creatine are useful parameters for grading gliomas, and the ratio of glycine to total creatine is useful for the differential diagnosis of glioblastoma from metastatic tumor. Such indications appearing in in vivo 1H-MR spectroscopy might provide clinically useful information on tumor metabolism and malignancy, and help assess the effects of radiation therapy and chemotherapy on gliomas.抄録全体を表示PDF形式でダウンロード (821K) -
Hiroyuki SHIMIZU, Yoshihisa OHTA, Ichiroh SUZUKI, Buichi ISHIJIMA, Mor ...1993 年 33 巻 6 号 p. 360-364
発行日: 1993年
公開日: 2006/06/20
ジャーナル フリーA newly developed lateral temporal polar surgical approach to the mesiobasal temporal region was applied to 25 consecutive patients with mesially confined temporal lobe lesions. This approach is characterized by a very limited resection of the lateral temporal cortex and a direct approach to the uncal area. The advantages of this method are clear orientation to the mesial temporal structures, easy access to the posteromesial part of the temporal lobe, and preservation of functionally important structures, such as the lateral temporal speech area, optic radiation, and temporal stem. Details of the surgical procedure are described.抄録全体を表示PDF形式でダウンロード (436K) -
Kyo NIIJIMA, Leonard I. MALLS1993 年 33 巻 6 号 p. 365-367
発行日: 1993年
公開日: 2006/06/20
ジャーナル フリーEighty-six (54%) of a series of 160 patients who underwent neurosurgery experienced postoperative cervicocephalic pain. We performed a superficial cervical plexus block (SCPB) immediately after operation in the subsequent 240 patients, in which the incidence of postoperative cervicocephalic pain was reduced to 27% (65 patients), and the intensity of pain was apparently milder. SCPB is a worthwhile procedure to prevent postoperative cervicocephalic pain.抄録全体を表示PDF形式でダウンロード (187K) -
Takahisa MORI, Masahiko ARISAWA, Shinya HONDA, Masaaki FUKUOKA, Koreak ...1993 年 33 巻 6 号 p. 368-372
発行日: 1993年
公開日: 2006/06/20
ジャーナル フリーPercutaneous transluminal angioplasty (PTA) was performed on supra-aortic arterial stenoses in two patients with concomitant cerebrovascular disease (CVD) and coronary artery disease (CAD). One patient had suffered small cerebral infarctions in the left frontal and temporo-occipital regions, and the other a lacunar stroke in the left pontine region. The former had stenosis of the left internal carotid artery as well as severe triple-vessel CAD. The latter had stenosis of the left subclavian artery as well as severe single-vessel CAD of the left circumflex artery. The PTA procedure successfully dilated the cervical arterial stenosis in both patients, while no cardiac complications occurred. In patients with concomitant CAD and CVD, PTA may be safer than endarterectomy or bypass grafts for supraaortic arterial stenoses.抄録全体を表示PDF形式でダウンロード (507K) -
Hidenobu OCHIAI, Tsutomu ISEDA, Satoshi MIYAHARA, Tomokazu GOYA, Shini ...1993 年 33 巻 6 号 p. 373-376
発行日: 1993年
公開日: 2006/06/20
ジャーナル フリーA rare case of rhinocerebral mucormycosis occurred in a 74-year-old diabetic male with gradually progressive right visual loss and total ophthalmoplegia. Computed tomography and magnetic resonance imaging revealed an invasive right orbital apex mass, destroying the medial wall of the orbit and extending into the right cavernous sinus and right middle fossa. Laboratory data demonstrated no signs of inflammation. A carcinomatous lesion originating in the paranasal sinuses and extending into the intracranial space was diagnosed. The mass was totally removed through a subfrontal approach to confirm the histological diagnosis and decompress the optic nerve. The histological diagnosis was mucormycosis. Despite aggressive medical therapy, dissemination resulted in mucor pleuritis and mucor encephalitis or meningitis. He died of septic shock and acute renal failure.抄録全体を表示PDF形式でダウンロード (356K) -
Chifumi KITANAKA, Masanori KUWAHARA, Akira TERAOKA1993 年 33 巻 6 号 p. 377-380
発行日: 1993年
公開日: 2006/06/20
ジャーナル フリーAn unusual, purely extramedullary hemangioblastoma of the spinal cord occurred in a 59-year-old female. Myelography revealed a filling defect at the Th6 level, and computed tomographic myelography demonstrated an extramedullary intradural isodense mass at the same level. The mass was homogeneously enhanced on postcontrast computed tomographic scans. T1-weighted magnetic resonance imaging showed an isointense mass, homogeneously enhanced by contrast medium. The tumor was removed en bloc.抄録全体を表示PDF形式でダウンロード (409K) -
Takayuki MATSUO, Hiroaki KOGA, Tadayoshi MORIYAMA, Mitsuto INAGAWA1993 年 33 巻 6 号 p. 381-385
発行日: 1993年
公開日: 2006/06/20
ジャーナル フリーA 53-year-old male presented with hearing impairment and facial nerve paralysis following tinnitus of the right ear. Neuroimaging revealed a tumor extensively damaging the temporal bone, and extending into the middle cranial fossa and cerebellopontine angle. The tumor was removed in a two-stage operation. The histological diagnosis was facial schwannoma.抄録全体を表示PDF形式でダウンロード (414K) -
Isao FUKASAWA, Shigeru MITSUKA, Hideaki NUKUI, Youji YOSHIDA, Hidehito ...1993 年 33 巻 6 号 p. 386-390
発行日: 1993年
公開日: 2006/06/20
ジャーナル フリーA 22-year-old male presented with granulomatous angiitis manifesting as headache. Computed tomography (CT) demonstrated a low-density area and ring-like enhancement in the right frontoparietal region. Steroid therapy caused rapid improvement in the signs and symptoms. Withdrawal of steroid was followed by recurrence of the headache and low-density area. The steroid treatment was resumed until he became asymptomatic 3 months after admission. He was followed up as an outpatient once every 2 weeks. One month after discharge, he complained of mild headache, and CT again demonstrated a mild increase in the low-density area. He was followed up continuously without steroid treatment. Two months after discharge, he suddenly lost consciousness, and CT demonstrated multiple intracerebral hematomas in the bilateral parietal regions. Removal of an intracerebral hematoma in the right parietal region and external decompression were carried out, but he died 3 days later. Histological examination of tissues from the right parietal cortex and leptomeninges demonstrated granulomatous inflammation with several giant cells in the vessels of the cerebral cortex and leptomeninges.抄録全体を表示PDF形式でダウンロード (576K) -
Masaaki YAMAMOTO, Christer LINDQUIST1993 年 33 巻 6 号 p. 391-394
発行日: 1993年
公開日: 2006/06/20
ジャーナル フリーWe describe here a new method of calculating the target point magnification rate for radiosurgery by stereotactic angiography using a Leksell frame. As the distance (D) between the x-ray focus and the film plane is constant in each facility, the magnification rate (M) is determined by the equation: M = D/[D/Mp + t], where Mp is the magnification rate of the proximal (to the x-ray focus) frame projected on the film plane and t is the distance between the proximal frame plane and the target point. The t value is given by the three-dimensionally determined stereotactic coordinates of the target point. Only the Mp value on the stereotactic angiogram must be measured. This method is theoretically more correct and has less risk of human error than the conventional, graphically determined method which necessitates measuring both the distal and proximal frame magnification rates. Furthermore, the inherent theoretical error of the conventional method is largest around the frame center, which is frequently selected as the target point for radiosurgical treatment, possibly causing serious error in accurate dose planning.抄録全体を表示PDF形式でダウンロード (225K)
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