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Volume 12, Issue 5
Displaying 1-6 of 6 articles from this issue
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Jun Igari, Yasuyuki Hayashi, Osamu Murase1975 Volume 12 Issue 5 Pages 291-297
Published: September 30, 1975
Released on J-STAGE: November 24, 2009
JOURNAL FREE ACCESSSince the introduction of quantification of bacteriuria by Kass in 1956, many studies on urinary tract infections have been reported. However, most of them was concentrated on the young and women of child bearing age. It is generally accepted that the incidence of urinary tract infection is high, and that it escapes clinical notice in a high proportion of patients, yet there have been few studies of the condition in the aged.
Our study was undertaken to determine the prevalence of significant bacteriuria and to investigate the sensitivity of predominating organisms to various antibiotics in the group of patients over the age of 65.
The patients were screened for the evidence of urinary white cell count and/or urinary tract symptoms. The urine specimen were taken by catheter and cultuered as soon as possible.
Of the 95 specimens examined, 63 (67.4%) were found to have significant number of organisms (greater than 100, 000 per ml urine). E. coli, Proteus, Enterococcus and Klebsiella were predominate organisms found. In 38 (60.3%) specimens single species were isolated, and in the remaining 25 specimens, mixed cultures were obtained.
In the drug-sensitivity patterns, E. coli was sensitive to KM, CL, AB-PC, CP, CER, NA, SM and TC in this order. Proteus was sensitive to SM, AB-PC, CP and CER.
Asymptomatic bacteriuria was noted 39.7% of 63 patients.View full abstractDownload PDF (803K) -
Katsuhiko Amemiya1975 Volume 12 Issue 5 Pages 298-305
Published: September 30, 1975
Released on J-STAGE: November 24, 2009
JOURNAL FREE ACCESSPsychiatric examinations were performed on the 100 patients who had survived from the acute stage of cerebro-vascular stroke. They were all right-handed, clear in consciousness and sixty years and over.
Seventy-six percents of the subjects showed more or less mental symptoms.
The patients were divided into the following 5 types according to their symptoms,
Type I (Simple recovery)……24 cases.
Type II (Simple dementia)……17 cases.
Type III (Psychotic with dementia)……21 cases.
Type IV (Psychotic without dementia)……31 cases.
Type V (Neuropsychologic)……16 cases.
(Type V was overlapped with Type II in 6 cases, with Type III in 2 cases and with Type IV in 1 case.)
The incidence of dementia was higher in the right-sided hemiplegics than the left, while that of the psychotic state was higher in the left-sided hemiplegics.
It was considered that causal genesis of dementia of these patients was due to cerebro-vascular stroke itself rather than to progressive arteriosclerotic narrowing of the cerebral arteries.
From psychiatric aspects, apoplexy in the elderly subjects is an especially important problem. More concerns should be paid on psychiatric states after stroke.View full abstractDownload PDF (1015K) -
Fumio Kuzuya, Noboru Yoshimine1975 Volume 12 Issue 5 Pages 306-310
Published: September 30, 1975
Released on J-STAGE: November 24, 2009
JOURNAL FREE ACCESSAuthors investigated the arteriosclerosis in pyridoxine deficient spontaneously hypertensive rats (SHR). SHR were divided into two groups. One group was feeded with pyridoxine deficient diet and the other was feeded no deficient diet (control) for 31 weeks. The arteriosclerosis as similar as these in pyridoxine deficient monkeys were observed on aorta and arteries in kidney, brain and the other portions in pyridoxine deficient SHR. That is to say, the fibrous plaque, duplication of internal elastic membrane and thrombosis were observed in pyridoxine deficient SHR. In SHR feeded with control diet, only a few pathological changes (the thickness and the production of elastic fibre) in media in small arteries were noticed.
It was supposed from above results that SHR have some hereditary factors increasing arteriosclerotic changes in pyridoxine deficient conditions or the hypertension will be a very important genetic factor for arteriosclerosis.View full abstractDownload PDF (2100K) -
Noboru Yoshimine, Fumio Kuzuya1975 Volume 12 Issue 5 Pages 311-314
Published: September 30, 1975
Released on J-STAGE: November 24, 2009
JOURNAL FREE ACCESSIn our previous paper, authors reported the effect of vitamin B6 (VB6) deficiency on short term feeding. In this paper, we will report the results on long term vitamin B6 deficient feeding in SHR (31 weeks).
-Results-
1) There were no significant changes in body weights through whole experiment. The body weights in VB6 deficient group, however, showed always lower levels.
2) The significant decreases of blood pressure (in tail) were obtained in VB6 deficient group after 15 to 20 weeks.
3) L-Aromatic amino acid decarboxylase (decarboxylase) activity in brain, kidney, and liver were significantly decreased in SHR. In this experiment, there were the significant decreases of enzyme activity in kidney and in liver of VB6 deficient SHR.
4) There were no significant changes of catecholamine contents in brain, kidney, and liver in both SHR groups.
From these results, we concluded that VB6 deficiency in long term feeding affected the almost all peripheral decarboxylase activity; at first in liver and then in other organs.
We will imagine that there is some balance (homeostasis?) between the central enzyme activity and the peripheral one, and that such balance was disturbed in long VB6 deficient feeding, causing the decrease of blood pressure. We also have much interest in the management of L-dopa and VB6 in Parkinsonism. From our papers, we can recommend that we had better not to get the large doses of VB6 in the treatment of the disease with L-dopa and the peripheral decarboxylase inhibitors.View full abstractDownload PDF (455K) -
Michihiro Kitagawa, Shunji Sawaki, Kenzo Hattori, Yukio Saito1975 Volume 12 Issue 5 Pages 315-320
Published: September 30, 1975
Released on J-STAGE: November 24, 2009
JOURNAL FREE ACCESSNitroblue tetrazolium (NBT) stain was investigated for the lipoprotein electrophoresis. This method has the advantages of being inexpensive, rapid, simple to apply and active in the absence of organic solvent. The pattern of lipoprotein separation was similar whether prestained with NBT or post-stained with Fat Red 7B or ozone schiff reaction. However, the mobility of pre-β band was faster in this method than in other conventional stains.
By means of immunoelectrophoresis and Laurell electrophoresis, NBT was shown to be a specific pre-stain for lipoproteins.
Among the other five kinds of tetrazolium; MTT, INT, NT, BT and TTC, which have been shown to be effective in the system of oxydase assay, only NT (Neotetrazolium) was effective for lipoprotein stain.View full abstractDownload PDF (1766K) -
1975 Volume 12 Issue 5 Pages 321-354
Published: September 30, 1975
Released on J-STAGE: November 24, 2009
JOURNAL FREE ACCESSDownload PDF (5641K)
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