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Volume 38 (1986)
- Issue 4 Pages 383-
- Issue 3 Pages 299-
- Issue 2 Pages 145-
- Issue 1 Pages 1-
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Volume 38, Issue 1
Displaying 1-9 of 9 articles from this issue
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Hiroshi Nakatani1986 Volume 38 Issue 1 Pages 1-40
Published: March 20, 1986
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSAn electrophysiological study was made on how the bladder movement was affected in unanesthetized rabbits when electric stimuli were given on the brainstem reticular formation (RF), the thalamus (VA, RET and VL) and the limbic system (the septum, the amygdala and the pyriform cortex). Furthermore, lower urinary tract dysfunction in patients with cerebrovascular disorders was compared with the finding obtained in the animal experiment. The results were as follows.View full abstractDownload PDF (8446K) -
Hiroshi Ikeda1986 Volume 38 Issue 1 Pages 41-48
Published: March 20, 1986
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESS(1), An electrophysiological study was made on the change of sleeping and waking rhythm in amygdaloid-kindled rabbits.
(2) Before the first stimulation, waking time was about 50% of 24 hours and REM sleep time was 4.7% of 24 hours. The former time was shorter and the latter was longer than those documented in previous reports.
(3) Waking time decreased to 40% and REM sleep time also decreased to 3.5% after the completion of kindling phenomenon.
(4) The tendency t h at waking time was shorter and slow-wave sleep time was longer before the first stimulation than those previously reported was reinforced after the completion of kindling phenomenon.
(5) Afte r the completion of kindling phenomenon, waking time decreased, slow-wave sleep time increased, and REM sleep time slightly decreased.View full abstractDownload PDF (1309K) -
Hiroshi Ikeda1986 Volume 38 Issue 1 Pages 49-60
Published: March 20, 1986
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSAn electrophysiological study was made on the change of heart rate in rabbits which were experimentally kindled either in amygdaloid nucleus, hippocampus, septal nucleus or cerebral cortex. The results obtained were as follows.
(1) After each stimulation, heart r ate decreased in every kindled group. The decrease of heart rate was most clearly seen in the amygdaloid nucleus-kindled group, followed by the hippocampus-, the cerebral cortex- and the septal nucleus-kindled group in that order.
(2) Heart rate between stimulations remained unchanged in the amygdaloid- an d the septal nucleus-kindled group, while it increased in the hippocampus-kindled group. Namely, there was observed permanent change of the heart rate in the hippocampus- and cerebral cortexkindled groups.
(3) B ased on the above results, it can be concluded that kindling phenomena produce permanent changes on the autonomic nervous system and the cardiac function as well. Accordingly, kindling phenomena are suggested to be eligible for an experimental model for cardiovascular symptoms caused by imbalance of the autonomic nervous system.View full abstractDownload PDF (2033K) -
Midori Nakazawa1986 Volume 38 Issue 1 Pages 61-74
Published: March 20, 1986
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESS67Ga scintigrams were taken of the head and neck of a normal control group (20 patients)of which the into 11 regions. Film density was measured to determine 67Ga citrate accumulation, and this data was used to create a quantitative standard of positivity for each region.
67Ga scintigrams were also taken of 131 patients with head and neck lesions (77 mal ignant tumor,33 benign tumor,21 inflammatory diease; 181 lesions in total). Positivity was then diagnosed quantitatively using the standard derived from the normal control group and the clinical applicability of this technique was investigated.
Result showed a clear significant diffe rence in 67Ga citrate accumulation between the malignant tumor group and the control group with the malignant tumor group accumulation higher in all regions. The benign tumor group showed a tendency towards no significant difference outside of the parotid region. The inflammatory disease group showed a wide range in accumulation with no tendency in common regions. The positive ratios were: malignant tumor group,81%; benign tumor group,47%; and inflammatory disease group,68%. Among positive cases, however the accumulation of benign tumor group was significantly lower than that of malignant tumor group. Sensitivity of the malignant tumor group was 81%; specificity,47%; and accuracy,70%.
The quantitative measurement of 67Ga citrate accumulaion was useful in the determination of positivity, indicating the possibility of positivity determination via automatic scintigram analysis.View full abstractDownload PDF (2906K) -
Relation to the Effect of Hyppocampal StimulationHiroe Naito, Hiroshi Ikeda, Yoshiteru Shiba, Mineo Okamoto, Masahiro N ...1986 Volume 38 Issue 1 Pages 75-87
Published: March 20, 1986
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSAs a part of the study to elucidate the influence of exteroceptive stimulation on the excitability of the brain stem reticular formation (RF) in presence of flash stimuli, the effect of hippocampal stimulation on the threshold of the RF was investigated in the rabbit and th e following observed.
1) The threshold of the arousal reaction appearing in the cerebral cortex EEG and the hippocampus (HPC) EEG and the evoked muscular discharge in the fore- and hind limbs, due to stimulation of the RF with 100 Hz was decreased by stimultaneous 100 Hz (0.2-1.0V)stimulation of the HPC.
2) The threshold of the arousal reaction and the evoked muscular discharge was increased by simultaneous 3 Hz (0.5-2.0V) stimulation of the HPC.
3) The decrease or increase in the threshold of the arousal reaction and the evoked muscular discharge following stimulation (100 Hz or 3 Hz) of the HPC, was abolished by destruction of the nucleus ventralis anterior or nucleus reticularis, which belong to the diffuse thalamocortical projection system. From these results, it w as concluded that the increase in excitability of the RF by HPC stimulation with 100 Hz, and the decline by stimulation with 3 Hz, can be attributed to a decrease in indirect inhibition and rise in indirect inhibition of the RF, respectively, via the diffuse thalamocortical projection system. The findings suggest that the previously reported increase in excitability of the RF by attachment of the contact lens in the presence of the flash stimuli (I), corresponds to the effect of 100 Hz HPC stimulation while the decrease in excitability of the RF by the contact lens in the absence of the flash stimuli corresponds to the effect of 3 Hz HPC stimulation.View full abstractDownload PDF (2406K) -
Yasuko Shiozaki, Yoshiko Sameshima, Jun Matsumoto, Takako Mizuno, Taka ...1986 Volume 38 Issue 1 Pages 88-102
Published: March 20, 1986
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSTo study abnormal carbohydrate metabolism accompanying liver diseases, we evaluated the changes in IRI, CRP and IRG following oral gllucose tolerance test, the results obtained were as follows.
1) Liv er diseases were frequently accompanied by abnormal carbohydrate metabolism. Glucose tolerance was abnormal in 37.5% of acute hepatitis and in 86.9% of liver cirrhosis.
2) Delayed hyper-responsiveness of IRI and CRP, and hyper-responsiveness as well as decreased inhibition of IRG were observed in many patients with liver disease. These findings were especially prominant in those with liver cirrhosis, suggesting increased functional activity of A and B cells. However, patients observed for 10 years showed hypo-responsiveoess of CRP and decreased IRG, indicating hypofunction of both A and B cell.
3) Significantly positive correlation were found between IRG and each of ICG, albumin and E/T ratio in liver cirrhosis, these findings strongly suggest that dysfunction of the liver is involved in the development of hyperglucagonemia in those with liver cirrhosis.View full abstractDownload PDF (2921K) -
Mariko Yamamoto, Yuji Kishimoto, Hiroyuki Kitajima, Hisanobu Uwamori, ...1986 Volume 38 Issue 1 Pages 103-109
Published: March 20, 1986
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSCase 1 was a forty-two year old man whose chief complaint was general fatigue. He had neither liver disease nor renal dysfunction. Though his serum amylase level was high,1106U, his urine amylase level was normal,241U. We suspected this pt. had macrnamylasemia. His serum amylase-isozyme pattern had special broad band and he had few normal amylase spot using Sephadex G-200 superfine thinlayer chromatography. These findings indicated that most of his serum amylase had large molecules. And we found his serum amylase was bound to lgA (K) using enzymatic immunofixation.
Case 2 was a fifty-thre e year old man who consulted our hospital because of the therapy for his diabetus mellitus. Though his serum amylase level was high,1051U, his urine amylase level was normal,187U. The characteristics of his serum amylase was similer to the first case's one.View full abstractDownload PDF (1770K) -
Fumiko Matsumoto, Toshihiko Matsumoto, Takuya Fujiwara, Yuko Kitao, Sh ...1986 Volume 38 Issue 1 Pages 110-115
Published: March 20, 1986
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSA 41-year-old man was admitted to our hospital with a chief complaint of stiffness and muscle atrophy of the right arm. He also showed a difficulty in swallowing and the occult blood of faces.
X-ray and endoscopic examinations of the stomach showed an irregular depression at the posterior wall of the upper body, IIc-like lesion with fold convergency at the greater curvature of the middle body, and decolouration and roughness of the mucosal surface on the posterior wall of the angle., Biopsy specimens from these lesions revealed tubular adenocarcinomas and total gastrectomy was performed. The resected specimen showed a 14.5×14.0cm superficial spreading of early cancer of IIb +IIc type. Histologically, a moderatoly differentiated tubular adenocarcinoma was localized mainly within the mucosa and it partially invaded the submucosa.
This patient was diagnosed also to have a spinal cord tumor. Upon operation this was found to have extended from C1 to C5 and the resection was impracticable. Histological diagnosis was astrocytoma grade II.View full abstractDownload PDF (1969K) -
Yasuo Yamanouchi, Nobuhiko Takahara, Kazuhito Miki, Yasuo Kawamura, Hi ...1986 Volume 38 Issue 1 Pages 116-123
Published: March 20, 1986
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSA case of neurofibromatosis associated with intracranial aneurysms and telangiectasia was reported. The patient was a 54-year-old woman with complaints of dementia and a spell of sudden sleep. On plain CT, a small round isodense lesion, which was clearly shown with contrast enhancement, was incidentally found in the right side of the pentagon. Right carotid angiogram showed an internal carotid artery aneurysm at the origin of the ophthalmic artery, fusiform dilatation at C1 portion of the internal carotid artery, and telangiectasia in the territory of the anterior choroidal artery. Left carotid angiogram also revealed an aneurysmal shadow in the internal carotid artery distal to the origin of the posterior communicating artery. Ten cases including the present case in which intracranial aneurysm was associated with neurofibromatosis have been reported so far. All but one case were female. In seven cases out of eight in which the site of aneurysm was documented, the aneurysm originated from the internal carotid system. Three cases out of ten were associated with cerebral arterial occlusion or stenosis accompanying Moya-Moya phenomena, but no cases other than the present case were reported to be associated with telangiectasia.
The pathogenesis of cerebral ane urysm formation in the case of neurofibromatosis was discussed and postulated that, in the present case, the hemodynamic stress from long-standing hypertension as well as mesodermal dysplasia of cerebral arteries resulted in aneurysm formation and fusiform dilatation of the internal carotid artery.View full abstractDownload PDF (2224K)
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