The Journal of Kansai Medical University
Online ISSN : 2185-3851
Print ISSN : 0022-8400
ISSN-L : 0022-8400
Volume 43, Issue Supplement
Displaying 1-3 of 3 articles from this issue
  • Toshio Uenoyama
    1991 Volume 43 Issue Supplement Pages S1-S13
    Published: 1991
    Released on J-STAGE: February 19, 2013
    JOURNAL FREE ACCESS
    Irritable bowel, syndrome (IBS) is a disease characterized by increased intestinal movement with abdominal pain and changes in bowel habit (either diarrhea or constipation), the clinical expression of which seems to be easily influenced by mental factors such as stress or emotion. To clarify the relationship between intestinal movement and mental activity, we studied the effect of electrical stimulation of subcortical nuclei, especially the limbic system, on intestinal movement. We used the balloon method on the ascending colon of rabbits. Acceleration of intestinal movement was found with 3 Hz stimulation to the corticomedial division of the amygdaloid nucleus (c-AMYG) and cortex pyriformis, and 100 Hz stimulation to the basolateral division of the amygdaloid nucleus (b-AMYG) and caudate nucleus (CAU). The acceleration was found to be due to the tonic effect of parasympathetic nerves. On the other hand, inhibition of intestinal movement was found with 100 Hz stimulation to c-AMYG,8 Hz stimulation to b-AMYG and 3Hz stimulation to b-AMYG and CAU. Although the inhibitory impulses were demonstrated to pass through the splanchnic nerve, the existence of some degree of adrenal influence was suggested.
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  • A Report of Two Cases
    Osamu Kameyama, Ryokei Ogawa
    1991 Volume 43 Issue Supplement Pages S15-S21
    Published: 1991
    Released on J-STAGE: February 19, 2013
    JOURNAL FREE ACCESS
    Two cases of sleeve fracture of the patella are reported. One occurred in the upper part of the patella, although this type of fracture usually affects the lower patella. The clinical features and mechanism of this fracture are reviewed in our patient and seventeen other cases reported in the literature. Treatment should be initiated immediately, with open reduction being performed to reduce the fragments accurately, because a large fragment of articular cartilage is also separated with the bone. Additionally, tight immobilization of such fractures, in adolescence, may induce aseptic necrosis of the patella.
    We therefore recommend the accurate reduction of the articular cartilage fragment and tension band wiring to immobilize this type of fracture.
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  • Shosaku Nomura, Terutoshi Kokawa, Kojiro Yasunaga
    1991 Volume 43 Issue Supplement Pages S23-S28
    Published: 1991
    Released on J-STAGE: February 19, 2013
    JOURNAL FREE ACCESS
    We investigated the relationship between ristoc etin-induced platelet agglutination (RIPA) and glycoprotein (GP) lib/Ilia. Aspirin, diltiazem, prostaglandin E1 caused disagglutination of RIPA, whereas an ADP scavenger or protein kinase C inhibitors did not. Monoclonal anti-GPIIb/IIIa and anti-GPIIIa antibodies, RGDS, or RGD caused disagglutination of RIPA, but not monoclonal anti-GPIIb antibody or HHLGGAKQAGDV. Binding of von Willebrand factor (vWf) to platelets increased 5 sec after ristocetin addition, but not that of fibrinogen (Fbg), fibronectin (FN), or thrombospondin (TSP). Binding of the latter 3 proteins to aspirin-treated platelets did not increase 15 min after ristocetin addition, but their binding to platelets incubated with RGDS increased 15 min after ristocetin addition. These results suggest that vWf binding to GPIb causes an increase of [Ca2±]i via thromboxane A2 synthesis, along with activation GPIIIa but not protein kinase C. Irreversible and full RIPA involves vWf binding to both GPIb and activated GPIIIa.
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