The status of the unexpected antibodies detected in blood donors or recipients and in the newborns with haemolytic diseases, using physiological saline test, high protein test, bromelin test and anti-globulin test in our blood transfusion unit were reported.
1.226 samples out of 12,875 samples were positive for unexpected antibodies. Anti-D, -E, -Le
a, -Le
b and -P
1 antibody were predominant among the antibodies.
2. It should be noteworthy that about 40% of anti-Le
a or Le
b antibodies, which may cause hemolytic diseases, were detectable only by anti-globulin test.
3. Among warm-type auto-antibodies showed Rh specific ity (anti-C, anti-E, anti-D antibody).
4. Among 160 samples from incompatible pregnancies,21 gave positive results: i. e.15concerning Rh system, and 6 ABO system.
5. Exchange transfusion were car ried out in 10 cases due to hemolysis caused by blood type incompatibilities: The antibodies detected were 1 anti-D,1 anti-D+ E,3 anti-E,2 anti-E-F c, as well as 1 anti-A and 2 anti-B. These results suggest the importance of E antibody, not only D antibody, for transfusion and pregnancy.
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