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Volume 43 (1991)
- Issue 4 Pages 369-
- Issue 1-2 Pages 1-
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Volume 43, Issue 4
Displaying 1-5 of 5 articles from this issue
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[in Japanese]1991 Volume 43 Issue 4 Pages 369-384
Published: December 20, 1991
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSDownload PDF (3147K) -
Masahiro Nagata1991 Volume 43 Issue 4 Pages 385-414
Published: December 20, 1991
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSElectrophysiological studies on the effect of hippocampal seizure were investigated in rabbits. When the seizure discharge was induced by hippocampal electric stimulation (100Hz,1 m sec,2.0-4.0V), followings were observed.
1) The threshold of both arousal reaction and evoked muscular discharge due to stimulation of the brain stem reticular formation (RF) increased.2) The frequency of spontaneous unit discharges of the brain stem reticular formation (RF-unit) decreased.3) The threshold of evoked muscular discharge due to stimulation of the cerebral cortex or the hippocampus (HPC) increased.4) Late components (N4-N7) of cortical somatosensory evoked potential to tibial nerve stimulation, were suppressed in amplitude.5) Some components (HN1, HN2, HN6) of hippocampal somatosensory evoked potential (SPE-HPC) to tibial nerve stimulation, also decreased in amplitude.6) The amplitude of the nociceptive reflex induced in tibialis anterior decreased.7)The amplitude of both M and H wave induced in gastrocnemius decreased.8) The amplitude of photoevoked eyelid microvibration (MV) was inhibited.9) There was no significant change in latency of 4) 8).10) In EEG topography the amplitudepower of the Delta, Theta, Alpha and Beta-1 waves decreased.11) Among these,1),2),3)-HPC,5),8), and 10) were eliminated after electric lesions in the nucleus ventralis anterior (VA), while the above-mentioned findings (1),3)-8)) were not observed after administration of either Barbiturate or Carbamazepine.
These results suggest that hippocampal seizure discharges suppress the function of RF, motor and reflex systems. Moreover, VA plays an important role on hippocampal impulses to spread out to cause these suppressive effects.View full abstractDownload PDF (5383K) -
Susumu Okubo, Tomoko Ishida, Kojiro Yasunaga1991 Volume 43 Issue 4 Pages 415-420
Published: December 20, 1991
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSIn Nov.1989, the Japanese Welfare Ministry enacted the "Guidelines for proper blood transfusion therapy" which urged us to proper use of blood components and plasma derivatives. In 1990,58,318 units in total of blood components and plasma derivatives were consumed, of which concentrated red cells (CRC) composing 15.7%, platelet concentrate (PC) 35.9%, and fresh frozen plasma (FFP) 48.4%. Compared with the number of the units used in 1987, CRC was stable, while PC rose up to 2.1 times and FFP to 1.4, respectively. The amount of FFP consumed in our hospital was much higher than that of average (33.6%) in Japan. On the other hand, although the proper ratio of C (cross matched units)/T (transfused units) should be less than 1.5, the ratio in our hospital was high; i. e.1.0-6.5, the mean 2.4. The ratio was particularly high in the surgical departments due to the excess reserve of blood components and plasma derivatives for their operations and to slow return of the unused blood products.
From Dec.,1990 to Jan.,1991, Type & Screen (T&S) and Maximum Bl ood Order Schedule (MSBOS) had been applied to 157 patients for trial; in almost all of them except for only two blood transfusions were unnecessary after all. Moreover, since July,1990,1402 units of FFP per month could be curtailed without any clinical troubles by means of cutting down the excess request for FFP. Hereafter, we have to accelate the application of T&S and MSBOS, along with the appreciation of the Guidelines and of our agreements covering blood banking services, in order to improve the efficiency of blood transfusion therapy in our hospital.View full abstractDownload PDF (1028K) -
Studies in Microcirculation and HemorhologyTakahide Hayashi1991 Volume 43 Issue 4 Pages 421-443
Published: December 20, 1991
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSSUBJECTS AND METHODS
In this report,56 patients in Oketsu state (24 of male and 32 of female) who were applicated to Keishi-bukuryo-gan, Toki-syakuyakuTsan were examined. In addition,24 patients (8 of male and 16 of male) who were applicated to Oren-gedoku-to were also examined. Ten patients of Oketsu state and 10 of Non-Oketsu state were examined before and after administration of Kanbaku-taiso-to.
Whole blood viscosities were measured at high shear rate (94.5 sec-1) and at low shear rate (0.376sec-1) by CONTRAVES Low Shear 30. R In order to know the erythrocyte deformab ilities, the passage times of 40% red blood cell suspensions were measured. Plasma passage time, peripheral blood changes (WBC, RBC, Hb, Ht, MCV, MCH, MCHC) and biochemical changes (TP, Alb, yGlb, ATIII, Fib) were also measured. Blood samples were withdrawn from elbow vein at before and 60 min. after administration of each drug of 5.0 grams.
An Intravital Videomicroscopic System (IVVMS) develop ed by Tsushima was used to observe and record the microcirculation kinetics and on the human bulbar conjunctiva. A Distance Meter Method developed by Tsushima was utilized for measurement of, the blood flow velocity.
Diameters of erythrocyte-colums were used as the internal diameters of blood vessels, excluding plasma sheath. Blood flow volumes were calculated by multiphying cross-sectional area and average blood flow velocity on the assumption that the vessel cross-section is circular.
Microcirculation was observed and measured at the same part of the same vessel before and 60 min. after administrations of drugs.
For the evaluation of "Oketsu" state, we used "Oketsu" score established by Terasawa.
All results are expressed as mean ± S. E., the significance is assessed using the pairedt test, the level of significance being calculated at p<0.05.View full abstractDownload PDF (9309K) -
Tohru Yamamoto, Nobuaki Matsuo, Hiroyasu Ishikura, Naoki Harada, Naosh ...1991 Volume 43 Issue 4 Pages 444-449
Published: December 20, 1991
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSAn adult case of idiopathic, intussusception was reported, and cumulative adult cases during a five-year period (1985-1989) in the Japanese literature were also analyzed.
A total of 109 cases including this case was collected. These adult cases rela tively lacked in clinical findings such as blood in the stool, palpable mass, and cramping abdominal pain, which were predominant in child cases. The majority of intussusception in adults were chronic or subacute in nature and acute obstruction was not the usual situation. In addition, the adult cases differed from child cases in predominantly having some definite mechanical causes including benign or malignant tumor.View full abstractDownload PDF (2001K)
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