Uirusu
Online ISSN : 1884-3433
Print ISSN : 0042-6857
ISSN-L : 0042-6857
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Volume 20, Issue 4
Displaying 1-7 of 7 articles from this issue
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  • Receptor for Japanese encephalitis virus
    [in Japanese]
    1970 Volume 20 Issue 4 Pages 265-272
    Published: December 01, 1970
    Released on J-STAGE: March 16, 2010
    DOIhttps://doi.org/10.2222/jsv.20.265
    JOURNAL FREE ACCESS
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  • LONG TERM SURVEILLANCE OF ACUTE UNDIFFERENCIATED FEBRILE ILLNESSES OCCURRED IN INFANTS AND CHILDREN OF THE NURSERY IN TOKYO
    THE ASPECTS OF RESPIRATORY VIRAL INFECTIONS
    Fumio NISHIKAWA, Miyako MATSUMOTO, Teiji SUGIYAMA, Hideo FUKUMI, Fujio ...
    1970 Volume 20 Issue 4 Pages 273-289
    Published: December 01, 1970
    Released on J-STAGE: March 16, 2010
    DOIhttps://doi.org/10.2222/jsv.20.273
    JOURNAL FREE ACCESS
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    Virological and epidemiological investigation of acute undifferentiated febrile illnesses, which occurred among a group of infants and children in the nursery of Tokyo from October, 1965 to December, 1968, were carried out by virus isolation and serological survey.
    Sixteen species of virus were isolated during this period. Among them, nine viruses, i. e. parainfluenza 1, 2, 3, 4A, adeno 1, 3, 5, echo 7 and coxsackie B1 were isolated from epidemic cases, four viruses, i. e. adeno 2, 6, coxsackie A9 and herpes simplex were from sporadic cases. The remaining three viruses, i. e. polio 2, 3 and vaccinia were considered as derived from the results of vaccinations. Epidemics of parainfluenza 2 and 3 viruses, and a complex epidemic of parainfluenza 2, echo 7 and RS viruses were observed in 1965, 1966 and 1967 respectively. RS virus infections were confirmed only by serological test. In 1968, two complex epidemics by coxsackie B1, parainfluenza 4A and adeno 5 viruses, and, parainfluenza 1 and adeno 1 viruses were proved.
    Results of serological investigations indicated that parainfluenza 2, 3, 4A, RS and echo 7 viruses spread effectively in this community. Especially parainfluenza 3 virus seemed to be the most effective spreader. Since high level of antibody titer against parainfluenza 3 virus had been kept in this group, repeated infection with this virus to the children having lowered antibody titer can be assumed. Our speculation is that, in Tokyo area, spreading of parainfluenza virus of each type gives the children many chances to get infections by these viruses every year. As to adenoviruses and enteroviruses, one type of virus will be replaced by another type of virus soon after the prevalence in this community.
    We could not find any specific differences in clinical informations among all the above virus infections. Most of cases showed mild upper respiratory syndroms.
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  • FIELD STUDIES ON IMMUNIZATION OF SWINES USING LIVE ATTENUATED JAPANESE ENCEPHALITIS VACCINE
    Natsumi TSUCHIYA, Toshiro KARAKI, Akio KURODA, Yoshiaki KAROJI, Osamu ...
    1970 Volume 20 Issue 4 Pages 290-300
    Published: December 01, 1970
    Released on J-STAGE: March 16, 2010
    DOIhttps://doi.org/10.2222/jsv.20.290
    JOURNAL FREE ACCESS
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    Since 1968 to 1970, field studies in immunization of pigs have been carried out in Kyoto city, to control the transmission of Japanese encephalitis virus (JEV) into mosquito population. One or one and half months before JE epidemic season, a total of 13, 900 pigs was vaccinated with the live attenuated Japanese encephalitis vaccine (m-strain) produced by Dr Inoue, No serious side reaction due to the vaccination was reported.
    The result of the vaccination was followed by the determination of the hemagglutination inhibition (HI) antibody level in pigs and by the survey of the infection rate of engorged mosquitoes caught in pig pens. To determine the HI antibody level, blood in visibly engorged mosquitoes was employed. The infection rate was calculated from the JEV isolation rate of engorged mosquitoes which had been incubated for 7-10 days after collection.
    HI antibody titers of 1:20 or 1:40 were observed in the vaccinated pigs although the secondary sharp rises were noted at a time when the wide spread of JEV was observed in nature. The infection rates of the pig pen administered with vaccine were markedly lower than the rates of those not vaccinated; the former was less than 1/2 of the latter at the highest point of the infection rates.
    These results suggest that vaccination on pigs seems to be applicable in the field to reduce the density of infected mosquitoes.
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  • A STUDY OF MUMPS EPIDEMIC IN INFANCY
    Shigeru IKEDA
    1970 Volume 20 Issue 4 Pages 301-311
    Published: December 01, 1970
    Released on J-STAGE: March 16, 2010
    DOIhttps://doi.org/10.2222/jsv.20.301
    JOURNAL FREE ACCESS
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    An institutional epidemic of mumps was seen among the infants under 2 years of age. Epidemiological, clinical and serological studies on the epidemic were carried out in 47 infants of the nursery. Furthermore by utilizing fluorescent antibody tests the influence of transplacental maternal antibodies on mumps infection of infants was studied. The significance of fluorescent antibody tests in mumps infection was discussed.
    The results obtained were as follows:
    1) An epidemic of mumps was found to occur even in infants around 1 year of age, when the proportion of susceptibles in the population was high and when they were in close contact with each other.
    2) Even the small amount of transplacental maternal antibodies, which were undetectable by hemagglutination inhibiting or neutralizing tests but detectable only by fluorescent antibody tests, might protect mumps infection in infancy.
    3) Fluorescent antibody tests were considered to be useful to determine whether the detected antibodies were due to natural mumps infection or of maternal origin: IgM mumps fluorescent antibody was specifically detected in sera of those who received recent infection of mumps.
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  • APPLICATION OF A MINICULTURE SYSTEM FOR ASSAY OF NEUTRALIZING ANTIBODY AGAINST POLIOVIRUSES
    Muneyuki MATSUDA, Koji KATORI, Kumiko MATSUURA, Takashi NAKAYAMA, Kent ...
    1970 Volume 20 Issue 4 Pages 312-316
    Published: December 01, 1970
    Released on J-STAGE: March 16, 2010
    DOIhttps://doi.org/10.2222/jsv.20.312
    JOURNAL FREE ACCESS
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    1) A miniculture system has been devised using a continuous Vero cell line in the Leibovitz-15 (L-15) medium supplemented with bovine albumin fraction V. A highly humid atmosphere required for the incubation was obtained in a desicator by placing a small vial filled with water.
    2) The above described system was applied to the titration of human sera for the poliovirus neutralization. A good correlation was obtained between this and the conventional tube method. Further more poliovirus serum neutralization by our system had a tendency of showing a little higher titer in the lower serum dilution area, and a little lower titer in the higher dilution area in comparison to the conventional tube method.
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  • [title in Japanese]
    1970 Volume 20 Issue 4 Pages 317-324
    Published: December 01, 1970
    Released on J-STAGE: March 16, 2010
    DOIhttps://doi.org/10.2222/jsv.20.317
    JOURNAL FREE ACCESS
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  • [title in Japanese]
    1970 Volume 20 Issue 4 Pages 325-331
    Published: December 01, 1970
    Released on J-STAGE: March 16, 2010
    DOIhttps://doi.org/10.2222/jsv.20.325
    JOURNAL FREE ACCESS
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