The second generation poly (amidoamine) dendrimer (PAMAM dendrimer) was prepared from ethylenedia-mine and methyl acrylate by a divergent method. The terminal amine groups of PAMAM dendrimers were modi-fied with carboxymethyl β-cyclodextrin by dehydration condensation using 1-ethoxycarbonyl-2-ethoxy-1, 2di-hydroquinoline. The ability in inclusion-complex formation of β-cyclodextrin, PAMAM dendrimer, and β-cy-clodextrin modified dendrimer was investigated by fluorescence and ultraviolet-visible absorption spectroscopies, where 8-anilino-l-naphthalene sulfonate and acid orange 7 were chosen as guest molecules. The observed spec-tral changes showed that the ability in inclusion-complex formation of β-cyclodextrin modified dendrimer was greater than that of β-cyclodextrin or PAMAM dendrimer.
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