巻号一覧
後続誌
23 巻 (1954)
- 6 号 p. 319-
- 5 号 p. 251-
- 3 号 p. 93-
- 2 号 p. 52-
- 1 号 p. 1-
23 巻, 2 号
選択された号の論文の8件中1～8を表示しています
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第1報 レシチン添加培地に於ける鼠癩菌の発育について戸田 忠雄, 三渕 一二1954 年 23 巻 2 号 p. 52-56
発行日: 1954/03/20
公開日: 2008/12/10
ジャーナル フリーThe media used for cultivation of M. leprae murium were based on the modified Kirchner's medium and contained polytamin, and glycerin, dextrose, soluble starch or glycogen was added to it as carbon source. Chemically pure lecithin and blood albumin were added to it for supplementary purposes.
It seemed that M. leprae murium could be grown on starch or glycogen-lecithinalbumin added medium at the initial culture and at the first subculture, but further subcultures were found impossible on this medium. The growth of M. leprae murium was worse on dextrose-lecithin-albumin medium, and worst on glycerin medium.抄録全体を表示PDF形式でダウンロード (672K) -
山岡 昭1954 年 23 巻 2 号 p. 56-63
発行日: 1954/03/20
公開日: 2008/12/10
ジャーナル フリーThe author made electron-microscopic specimens from homogenates of the Human Leprosy Nodule (Leprom) which had been aseptically removed and observed electron-microscopically. The results are as follows:
(1) The size and shape of M. leprae under electron-microscopic observation are approximately identical with an optical view after strong staining (Fig. 5-22).
(2) Although different specimen making process from the case of optical microscope were adopted, identical images with old optical observation were gained as regards the arrangement of bacilli: M. leprae were placed alone, gathered irregularly, placed side by side like cigar bundles or gathered in round masses. These views were identical with optical observation (Fig. 5-22).
(3) Two types were found in M. leprae morphologically, one is a granular type and the other homogeneous. In granular type, the bacilli which have dense masses that appear like large polar bodies are predominant (Fig. 3 and 4, 5-22).
(4) Some bacilli have a belt-like structure covering almost equal to the width of bacilli. But the nature of this structure is still left unknown (Fig. 21 and 22).
(5) It was observed that in some bacilli there were small round bodies (150-200 mμ in diameter) like the flowers of chrysanthemum inside or outside the bacilli. These small bodies are being studied (Fig. 8).
This report was presented at the Conference of West District, Leprosy Society of Japan, Hiroshima, November 8, 1953.抄録全体を表示PDF形式でダウンロード (1610K) -
川口 陽一郎1954 年 23 巻 2 号 p. 64-68
発行日: 1954/03/20
公開日: 2008/06/30
ジャーナル フリーThe present paper describes the results of hemagglutination test with tuberculinsensitized red cells on the sera of the white rats inoculated with the rat leprosy bacilli.
1) Experiment A. Fifteen of 16 infected animals showed positive reaction, with the hemagglutination titres being from 1: 4 to 1:128.
2) Experiment B. In the early stages of the infection, all the sera of inoculated animals demonstrated negative reactions. Only the two animals became positive 6 months after inoculation.
3) Hemagglutination titres seem not to correlate with the weight of superficial leproma, but to the grade of leprous changes of visceral organs.抄録全体を表示PDF形式でダウンロード (370K) -
第1報 PAShydrazideの合成並びにその鼠癩発症に及す影響吉永 敏夫, 加来 天民1954 年 23 巻 2 号 p. 68-71
発行日: 1954/03/20
公開日: 2008/12/10
ジャーナル フリー1. We synthesized PAShydrazide for the treatment of leprosy.
2. PAShydrazide prevents tolerably. the development of murine leprosy
3. The effect of Pashydrazide upon murine leprosy is almost the same as that of PAS or INAH.抄録全体を表示PDF形式でダウンロード (469K) -
鼠癩の研究(25)高山 保郎1954 年 23 巻 2 号 p. 71-74
発行日: 1954/03/20
公開日: 2008/12/10
ジャーナル フリーEvaluating the influence of INAH on rat leprosy, based upon the degree of enlargmert of leproma and dissmlnation of leprosy bacilli into tissues, it seemes to be much or less active for the inhibition of the development of and therapeutic effect on rat leprosy in hamster.抄録全体を表示PDF形式でダウンロード (545K) -
第13報 鼠癩に対する抗生物質の影響西村 真二, 河野 通之, 増田 太郎1954 年 23 巻 2 号 p. 74-81
発行日: 1954/03/20
公開日: 2008/06/30
ジャーナル フリーExperimental studies were carried out on the inhibitory action of antibiotics on development of murine leprosy. Those antibiotics, Acidomycin (AM) (Thiazolidone Antibiotics of McLamor et al.), Streptomycin (SM) and Aureomycin (AUM) were studied and the results are presented below.
1. Acidomycin does not have an inhibitory action on the development of murine leprosy. (Fig. 1, 3 and 4)
2. Streptomycin has a moderate inhibitory effect on the development of murine leprosy. (Fig. 2, 3 and 4)
3. Aureomycin possesses no inhibitory action on the development of murine leprosy. (Fig. 5)
From these results and the results of previous studies chemotherapeutic agents, it is believed that antibiotics which are ineffective in experimental tuberculosis are also in- effective in preventing development of murine leprosy.抄録全体を表示PDF形式でダウンロード (502K) -
中島 一1954 年 23 巻 2 号 p. 81-84
発行日: 1954/03/20
公開日: 2008/12/10
ジャーナル フリーI have studied on the therapeutic effects of proethyl in relation to the development of rat leprosy. The results were as follows.
1) The mortal dose of proethyl is DL 50-93. 64mg/10 gr by subcutaneous injection of this drug and DL 50-442.5mg /10gr by its internal dosage.
2) The density of proethyl in blood was appeared the highest after the internal dosage during 2 hours, and half degrees after 5 hours. This density of proethyl could be measured by 24 hours.
3) The therapeutic effectiveness of this drug on rat leprosy was based upon the degree of the enlargement of leproma and the dissemination of lepra bacilli into tissues. It was appeared a little effect on rat leprosy.抄録全体を表示PDF形式でダウンロード (489K) -
楳木 旺栄1954 年 23 巻 2 号 p. 85-90
発行日: 1954/03/20
公開日: 2008/12/10
ジャーナル フリーTwenty leprous patients with neuralgia and arthrodynia were treated with Nitromin by intravanous or local injection.
It was remarkably effective in 12 cases, moderatly in 2 cases, but ineffective in 3 cases and the effect was indefinite in another 3 cases.抄録全体を表示PDF形式でダウンロード (801K)
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