MEMBRANE
Online ISSN : 1884-6440
Print ISSN : 0385-1036
ISSN-L : 0385-1036
Volume 22, Issue 2
Displaying 1-6 of 6 articles from this issue
  • Tatuo Hiyoshi, Makoto Miyazaki, Makoto Fukuda
    1997 Volume 22 Issue 2 Pages 74-80
    Published: March 01, 1997
    Released on J-STAGE: March 04, 2011
    JOURNAL FREE ACCESS
    Most of requirements for hemodialysis hollow fiber membranes depend on their micro pore structure and distribution. Therefore, not only the averaged pore radius but also the pore radius distribution should be noted in the optimal design of hollow fiber hemodialysis membranes. Herein some advantageous characteristics of newly developed cellulose hemodialysis membrane, pore radius distribution pattern of which may be so called “symmetricall gradient structure”, are presented with those of the conventional and well known homogeneous, gradient, and reverse gradient structure membranes.
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  • Hiroyoshi Kawakami, Shoji Nagaoka
    1997 Volume 22 Issue 2 Pages 81-87
    Published: March 01, 1997
    Released on J-STAGE: March 04, 2011
    JOURNAL FREE ACCESS
    We have synthesized fluorinated polyimides to develop a novel membrane oxygenator combining excellent gas transfer and blood compatibility. Recent major advances for membrane oxygenator have led to the development of a new device for the performance of extrapulmonary gas exchange. This device is called the intravascular oxygenator (IVOX) and a temporary implantable intravascular membrane oxygenator that is designed to transfer gas intravenously. In this paper, preliminary results of gas exchange and biocompatibility of fluorinated polyimide membrane have been reported.
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  • Kiyoshi Ishii, Misao Yasui
    1997 Volume 22 Issue 2 Pages 88-95
    Published: March 01, 1997
    Released on J-STAGE: March 04, 2011
    JOURNAL FREE ACCESS
    Among many endotoxin rejecting membrane applications in medical use, endotoxin removal from dialysate becomes one of the focuses in hemodialysis.
    In order to achieve both high flux and high endotoxin rejection, an UF module of molecular weight cut-off of 100 thousand Dalton was developed. By use of this filter the average endotoxin concentration in clinical dialysate over 14 months was below 10 EU/l, the most strict target to be achievd.
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  • Molecular hypothesis not only explainning various phenomena without contradiction, but also predicting various yet-unobserved phenomena
    Kunihiko Goto
    1997 Volume 22 Issue 2 Pages 96-104
    Published: March 01, 1997
    Released on J-STAGE: March 04, 2011
    JOURNAL FREE ACCESS
    Following the preparation of cell-sized bilayered liposomes in 1980, we developed a thermodynamic theory about various cellular functions, which we call the “rotation model”. That model not only explains various phenomena of cellular functions, but also predicts various yet-unobserved phenomena.
    Recently, we published the rotation model as applied to the molecular mechanisms of the nicotinic acetylcholine receptor ion channel (nAChR). We then succeeded in the quantification of the rotation model with regard to molecular recognition. The essential principle is that, in water, the hydrophobic interaction itself is the binding energy of molecular interactions (ΔGtransfer) and water molecules on the hydrophilic molecular surface bound by the hydrophilic interaction impede the molecule-molecule binding, the entropic term (TΔSassoc) :
    ΔGassoc= ΔGtransfer-TΔSassoc
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  • Noboru Kubota, Yoshitaka Konno, Kyoichi Saito, Kazuyuki Sugita, Kohei ...
    1997 Volume 22 Issue 2 Pages 105-110
    Published: March 01, 1997
    Released on J-STAGE: March 04, 2011
    JOURNAL FREE ACCESS
    Protein binding amounts of the modules consisting of anion-exchange porous membranes were determined as a function of flow rate of the protein solution. Two kinds of anion-exchange porous membranes of a hollow-fiber form were compared : EA membrane containing a 2-hydroxylethylamino group and DEA-EA membrane containing a diethylamino group along with the 2-hydroxylethylamino group. The module has an inner diameter of 1.8 cm and effective length of 8 cm, respectively, into which nine or eight numbers of the anion-exchange porous hollow-fiber membrane (ID=2.8 mm, OD=4.4 mm) were incorporated. A 2 kg/m3 bovine serum albumin (BSA) in a Tris-HCl buffer (pH 8.0) was fed to the module from the lumen side to the shell side at various flow rates. The dynamic binding amount of BSA calculated from breakthrough curves was constant irrespective of flow rate ranging from 0.17×106 m3/s to 1.7×106 m3/s because of a negligible diffusional mass-transfer resistance assisted by convective flow through the pores. The DEA-EA module exihibited about three-fold equilibrium binding amount of BSA compared to the EA module. This can be explained by multilayer binding of BSA into the polymer chains grafted onto the pore surface.
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  • Mutsuo Kawasaki, Ichiro Kawada
    1997 Volume 22 Issue 2 Pages 111-113
    Published: March 01, 1997
    Released on J-STAGE: March 04, 2011
    JOURNAL FREE ACCESS
    Ultra-low pressure RO membrane module “ES series” and high performance under operating pressure of 0.7 MPa. The ES series requires about half of the operating pressure as most commonly available aromatic polyamide composite RO membranes, so they can save energy costs and initial costs.
    The ES series consist of 3 types, that is, “ES10”, “ES15” and “ES20”. “ES10”, is a base grade, in which NaCl rejection is 99.5% and permeate flux is 30 m3/day at 0.7 MPa. “ES15” has higher permeate flux, and “ES20” has higher NaCl rejection than that of ES10. All types have 2 grades for their usage, that is, desalination of tap water and making of ultra pure water.
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