Online ISSN : 1884-6440
Print ISSN : 0385-1036
Volume 42 , Issue 6
Showing 1-4 articles out of 4 articles from the selected issue
Special Topic:ICOM 2017
Original Contribution
  • Hirotaka Noda, Shohei Moriyama, Kei Irie, Kazumasa Fujita, Taku Yokoya ...
    2017 Volume 42 Issue 6 Pages 242-249
    Published: 2017
    Released: January 13, 2018
    Plasmalogen in phospholipid class is ubiquitously found in biological membrane. Although oxidative stress is involved in human atherosclerosis and this unique phospholipid may play a role as an endogenous antioxidant, there still remains a debate concerning the role of plasmalogen in human atherosclerosis. To investigate the relationship between plasmalogen and atherosclerosis, plasmalogen in plasma and erythrocyte membrane was quantified in atherosclerotic patients (n = 20) and age–matched control subjects (n = 20) using high–performance liquid chromatography (HPLC). In the HPLC of plasma treated with phospholipase A1, concentrations of choline plasmalogens (pl–PC) and ethanolamine plasmalogens (pl–PE) in atherosclerotic patients were significantly lower than the respective concentrations in healthy controls. In the HPLC of erythrocyte membrane phospholipid extract, the peak area of pl–PE in atherosclerotic group was reduced significantly relative to that in control group. This study demonstrated that plasmalogen in plasma and erythrocyte membrane is diminished in patients with severe atherosclerosis requiring endovascular therapy. Further studies are required to elucidate the clinical role of plasmalogen as a laboratory marker in severe atherosclerotic patients.
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Rapid communications
  • Hao-Chen Wu, Tomohisa Yoshioka, Keizo Nakagawa, Takuji Shintani, Toshi ...
    2017 Volume 42 Issue 6 Pages 250-254
    Published: 2017
    Released: January 13, 2018
    In this study, water–molecule transport properties of an Amphotericin B–Ergosterol (AmBEr) channel were examined on a molecular level via simulation of the forward osmosis (FO) filtration phenomena. FO filtration and doublelayer channel (DLC) AmBEr channel models were constructed via molecular dynamics (MD). MD simulation was adopted to explain the diversity transport mechanism of a novel AmBEr channel, and the channel performance was compared with that of actual AmB channel membranes and a commercial polyamide membrane. AmBEr water channel not only showed more than 100–fold greater permeability than polyamide membrane, but also completely rejected Na+ and Cl– ions during the simulation time of 4.5 ns.
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Products Spotlight
  • Kenji Fukuda, Masayuki Kishino, Kiyotaka Yoshie
    2017 Volume 42 Issue 6 Pages 255-258
    Published: 2017
    Released: January 13, 2018
    Novel ion–exchange membrane has been developed using non–woven fabric as the reinforcement, to prepare cost effective membrane not only for the traditional electrodialysis process but also for the new application like reverse electrodialysis (RED) or membrane capacitive deionization (MCDI), where the cost of the membrane is quite important. For the preparation of non–woven fabric membrane, new procedure has been adopted, where ion–exchangeable polymer solutions were coated on the non–woven fabric. Non–woven fabric membranes prepared have the lower membrane resistance compared to those of conventional ion–exchange membranes, keeping its transport number almost same level. With applying these new membranes, electrodialysis and reverse electrodialysis performances were investigated.
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Editor's note