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Volume 48 (2023)
- Issue 6 Pages 254-
- Issue 5 Pages 214-
- Issue 4 Pages 160-
- Issue 3 Pages 94-
- Issue 2 Pages 56-
- Issue 1 Pages 2-
Volume 48, Issue 5
Displaying 1-9 of 9 articles from this issue
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Special Topic : Young Researchers Tell Us "Membrane Science and Technology toward the Next Era", Part 2
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Natsuko F Inagaki2023 Volume 48 Issue 5 Pages 214-217
Published: 2023
Released on J-STAGE: October 02, 2023
JOURNAL RESTRICTED ACCESSRepeated hepatectomy is widely accepted as one of the most curative treatment for recurrent hepatocellular carcinoma or liver metastasis from colorectal cancer. However, repeated hepatectomy has two critical issues; postoperative adhesion and decrease of liver regenerative activity. Postoperative adhesion makes surgical operations technically more demanding, leading to increased mortality and morbidity rates. Although the liver has a remarkable ability of regeneration, volume and functional restoration after multiple repeated hepatectomy is not generally complete. So a new procedure that overcomes these two issues is demanding. I focused on liver mesothelial progenitor cells. Using a novel mouse hepatectomy model that reproduces postoperative adhesion on the resected liver surface, it was revealed that the liver mesothelial progenitor cell sheet effectively prevented postoperative adhesion and facilitated liver regeneration by providing growth factors for hepatocytes. These results showed that the liver mesothelial progenitor cell sheet could solve these two clinical issues simultaneously. Additionally, an allogeneic liver mesothelial progenitor cells sheet showed as effective as a syngeneic cell sheet. Furthermore, I have established the differentiation protocol of induced pluripotent stem cells (iPSCs)–derived liver mesothelial progenitor cell and proved that it had the ability to suppress the postoperative adhesion and facilitate liver regeneration. Liver mesothelial progenitor cells may serve as a potentially useful cell source for regenerative medicine after hepatopancreatobiliary surgery.View full abstractDownload PDF (710K) -
Shun Aoyama, Hiroki Nagasawa2023 Volume 48 Issue 5 Pages 218-222
Published: 2023
Released on J-STAGE: October 02, 2023
JOURNAL RESTRICTED ACCESSPlasma surface modification has been used in various material applications, including membranes, to add useful functionality to the surface in a dry condition with low environmental impact. In particular, surface modification using atmospheric–pressure low–temperature plasma is promising compared to that uses conventional low–pressure plasma owing to its unique property, namely, operation without vacuum environment, easy scale–up, and potential open–air treatment. In this review, we summarize the applications of plasma surface modifications in membranes to improve their permeation properties. We also introduce our latest research on the surface modification of organosilica membranes with atmospheric–pressure water vapor plasma to control their permeation properties. The plasma– modified organosilica membranes showed improved permselectivity in pervaporation dehydration because of increased hydrophilicity and well-tuned pore size at the membrane surface, demonstrating a facile modification strategy under atmospheric pressure and at room temperature. We will also provide perspectives on plasma–assisted processing for future membrane engineering to control membrane structure and permeation properties.View full abstractDownload PDF (1081K) -
Kohjiro Nagao2023 Volume 48 Issue 5 Pages 223-225
Published: 2023
Released on J-STAGE: October 02, 2023
JOURNAL RESTRICTED ACCESSI have been studying the regulatory mechanisms of the structure and distribution of membrane lipids in animal cells. Why did I choose this research subject ? Furthermore, why do I think I will continue to study it in the future ? I would like to introduce myself by sharing my thoughts on these questions from the perspective of a young researcher and educator.View full abstractDownload PDF (585K) -
Takuya Ogawa2023 Volume 48 Issue 5 Pages 226-229
Published: 2023
Released on J-STAGE: October 02, 2023
JOURNAL RESTRICTED ACCESSBiological membranes comprise phospholipids that are acylated with various fatty acids. The fatty acid compositions of bacterial biomembranes are properly regulated to maintain membrane homeostasis and alleviate external stresses. Although the substrate selectivity of acyltransferases that introduce fatty acyl groups during de novo phospholipid biosynthesis is supposed to be one factor regulating the fatty acid compositions, their enzymatic and physiological functions are poorly studied. In this minireview, how bacteria regulate the membrane fatty acid compositions via the acyltransferase system and how it is relevant to cell physiology are presented.View full abstractDownload PDF (680K) -
Shiho Yada2023 Volume 48 Issue 5 Pages 230-234
Published: 2023
Released on J-STAGE: October 02, 2023
JOURNAL RESTRICTED ACCESSSurfactants are amphiphilic compounds with functional groups having opposite properties of hydrophobic and hydrophilic groups in a molecule. Surfactants are used in a wide range of industrial fields such as detergents, cosmetics, foods, pharmaceuticals, paints, and agrochemicals, because they adsorb at the interface to change significantly their properties, and various functions such as washing, emulsifying, dispersing, solubilizing, foaming, and defoaming. To improve the properties and various functions for existing surfactants, various novel surfactants have been developed. In this review, we report the works of (1) structural analysis of micelles formed by polyoxypropylenepolyoxyethylene type nonionic surfactant with a single chain–length by using small–angle X–ray scattering (SAXS), and (2) structural analysis of foams formed by sodium polyoxyethylene alkyl ether sulfate ester surfactant by using small–angle neutron scattering (SANS).View full abstractDownload PDF (776K) -
Atsushi Matsuoka2023 Volume 48 Issue 5 Pages 235-239
Published: 2023
Released on J-STAGE: October 02, 2023
JOURNAL RESTRICTED ACCESSA novel O2 separation membrane with O2 reactive metal–containing ionic liquids (MCILs) as the O2 carrier was presented. To develop the O2 absorbable ILs, N, N '–bis(salicylidene)ethylenediamine cobalt(II) (Co(salen)) was adopted as the O2 reactive substance. When Co(salen) was mixed with specific ILs of which anion has amino group, the Co(salen) coordinated with the anion got the negative charge. Then the negatively charged Co(salen) with bulky cations could act an MCIL. Then, the gas permeability of a supported IL membrane (SILM) with the MCIL was evaluated. As the result, O2 permeability was strongly affected by O2 partial pressure. This result indicated that synthesized MCIL acted as O2 carrier in the membrane. The developed SILM showed higher O2 permeability than previously reported facilitated transport membranes with fixed O2 carrier. Thus, the ionic liquid–based O2 carrier would be effective to develop the facilitated O2 transport membrane with high O2 permeability.View full abstractDownload PDF (1317K) -
Masaya Miyagawa2023 Volume 48 Issue 5 Pages 240-243
Published: 2023
Released on J-STAGE: October 02, 2023
JOURNAL RESTRICTED ACCESSLayered materials have well–defined two–dimensional interlayer space and can form membrane spontaneously. Layered clay minerals are the representative example, and have been hybridized with organocations, functional molecules and polymers. In this short review, membrane–related functions by the clay are briefly demonstrated.View full abstractDownload PDF (827K) -
Yosuke Senju2023 Volume 48 Issue 5 Pages 244-247
Published: 2023
Released on J-STAGE: October 02, 2023
JOURNAL RESTRICTED ACCESSMembrane studies have long been an active field in Finland, and has many prominent researchers. There, I studied lipid–protein interactions using biophysical techniques. I have utilized liposomes and giant unilamellar vesicles (GUVs) to investigate the biophysical properties of actin–regulatory proteins and membrane curvature sensing/generating BAR domain proteins, such as membrane binding affinities and modes, lateral diffusion and association/dissociation dynamics on the membranes, and their physiological relevancies in cells. During my stay at the University of Helsinki, I collaborated with many researchers in Finland and other European countries such as the United Kingdom, Germany, and France. Communicating in English is fine in Finland due to the high–quality education system. Gender balance is well–considered in Finland. The Finnish, including PIs, are friendly and open–minded to the discussion. Here, I would like to introduce my study and life experience in Helsinki. I hope this will be helpful for young researchers who are considering studying abroad in the future.View full abstractDownload PDF (760K)
Products Spotlight
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Shinsuke Hirata2023 Volume 48 Issue 5 Pages 248-251
Published: 2023
Released on J-STAGE: October 02, 2023
JOURNAL RESTRICTED ACCESSPressure–retarded osmosis (PRO) is a promising system for renewable energy. The system utilizes a spontaneous hydraulic water stream driven by the osmotic pressure difference between brine with high concentration of salts and freshwater, and then the hydraulic water stream is subsequently converted into electricity using a turbine and generator. Because a spontaneous hydraulic water stream is produced by a semi–permeable membrane, the development of high–performance PRO membrane modules is quite important for making the PRO system commercially feasible. Based on well–established reverse osmosis membrane technology for more than 40 years, Toyobo MC has developed and commercialized hollow–fiber PRO membrane consisting of cellulose triacetate, which shows a larger hollow– fiber membrane dimension (inner/outer diameter = 135/300 μm) and robustness. SaltPower, a start–up company in Denmark, uses high salinity solutions (more than 10 wt%) as draw solutions to achieve a commercial PRO plant. Toyobo MC’s PRO membrane modules have been offcially adopted by SaltPower, and the first commercial PRO plant is currently being commissioned.View full abstractDownload PDF (805K)
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