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Volume 37 (2012)
- Issue 6 Pages 264-
- Issue 5 Pages 212-
- Issue 4 Pages 164-
- Issue 3 Pages 108-
- Issue 2 Pages 59-
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Volume 37, Issue 6
Displaying 1-8 of 8 articles from this issue
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Special Topic: A “Bio-Inspired” View of “Membrane Science and Technology”
Review Article
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Hiroshi Umakoshi, Toshinori Shimanouchi, Keishi Suga2012 Volume 37 Issue 6 Pages 264-269
Published: 2012
Released on J-STAGE: September 16, 2014
JOURNAL OPEN ACCESSIt is important to establish a methodology to design and develop a “Bio-Inspired Membrane”, which can be defined as an “Artificial Membrane” inspired by structures and functions observed in “Biomembrane”. Several approaches relating to this research area are reviewed based on a hierarchical view about the structures and characteristics of the above membranes. A “Membranome” research utilizing a gel membrane immobilizing liposome membrane at high concentration is herewith introduced as one of several approaches to create the “Bio-Inspired Membrane”. Some possible data required for the “Bio-Inspired Membrane” are finally discussed, focusing on the physicochemical property of self-assembly included in a total system.View full abstractDownload PDF (1208K) -
Makoto Yoshimoto2012 Volume 37 Issue 6 Pages 270-275
Published: 2012
Released on J-STAGE: September 16, 2014
JOURNAL OPEN ACCESSIn liposome suspensions, enzyme reactions can be induced under the condition where the enzymes are isolated from the bulk liquid. The rate of liposomal enzyme reaction is often limited by the transfer of substrates from the bulk liquid to the liposome interior through lipid bilayer membranes. We have applied these characteristics of liposomes to modulate the stability and apparent reactivity of several oxidoreductases. Furthermore, the rate of liposomal reaction can be improved by suspending the enzyme-containing liposomes in gas-liquid flow, as observed for the oxidation of glucose in an external loop airlift bubble column. Permeability of 5 (6)-carboxyfluorescein through membranes of liposomes with mean diameter of about 100 nm increased under the fluid shear stress generated in a cone-and-plate geometry. Fluid shear stress in the airlift bioreactor was thus suggested to be responsible for the permeabilization of liposomes in the oxidation reaction. The liposomal enzyme would function as a fluid propertyresponsive catalyst in practical bioreactors.View full abstractDownload PDF (942K) -
Kenichi Morigaki2012 Volume 37 Issue 6 Pages 276-281
Published: 2012
Released on J-STAGE: September 16, 2014
JOURNAL OPEN ACCESSSubstrate supported phospholipid bilayers are model systems of the biological membrane that offer possibilities for integration (micro-patterning) and sensitive analyses. We developed hybrid membranes composed of polymerized and fluid bilayers. Since the polymeric bilayer provides a robust framework for incorporating various types of lipid membranes, it can be applied to study the functions of membrane-bound proteins and peptides. Amyloid fibril formation has been studied using micro-patterned supported membrane. Since the hybrid membranes are both stable and functional, they should provide a new avenue for generating robust model systems for the basic study of membrane functions as well as biomedical applications.View full abstractDownload PDF (754K) -
Yoshiko Miura, Hirokazu Seto, Tomohiro Fukuda2012 Volume 37 Issue 6 Pages 282-287
Published: 2012
Released on J-STAGE: September 16, 2014
JOURNAL OPEN ACCESSSaccharides on the cell surfaces are displayed in a multivalent manner. We mimicked the multivalent saccharide display with the artificial glyco-thin-layer. The multivalent saccharides were immobilized on the substrate, and the saccharide-protein interaction was analyzed using the substrate properties. The artificial glyco-thin-layer was functionalized as biosensor. In addition, the saccharide display was regulated with well-defined multivalent structure of glyco-dendrimers. The glyco-dendrimer was immobilized on the substrate, and amplified the interaction with sugar recognition protein. The sufonated-GlcNAc immobilized dendrimer showed the strong interaction to Alzheimer Amyloid beta peptide, and the biological activity of Amyloid beta peptide was controlled by the multivalency of saccharide substrate.View full abstractDownload PDF (797K) -
Hidenori Kuroki, Takeo Yamaguchi2012 Volume 37 Issue 6 Pages 288-296
Published: 2012
Released on J-STAGE: September 16, 2014
JOURNAL OPEN ACCESSIn biological systems, various components at multiple levels from small molecules to organs work coordinately to perform their advanced and non-linear functions. Such biological systems are attractive and useful for developing new materials. In our strategy for development of a new material, we consider materials as one system; several element materials are systematically arranged, and each element materials work coordinately as one system to perform desired functions. Here, using our strategy as “systematic material design”, we propose a biomolecule-recognition gating membrane that immobilizes the stimuli-responsive polymer, including the biomolecule-recognition receptor, onto the pore surface of a porous membrane. The cooperation of biorecognition crosslinking and polymer phase transition in nanosized pores enables the selective conversion of a biomolecular signal via the control of a pore gating (opened/closed) into the clear change in water permeability or color. Moreover, we clarified, from a microscopic point of view, the relationship between the property of grafted polymers in pores and the permeation behavior of a stimuli-responsive gating membrane. The obtained knowledge allows the estimation of the response sensitivity to a biomolecular signal in our proposed gating system. The modeling estimation indicates the possibility of developing a more advanced gating membrane with an ultrahigh sensitivity. The above-described features have never been achieved by the previously-reported responsive hydrogels and gating membranes, and thus our new gating system should provide a new direction in designing novel bio-devices in widespread fields.View full abstractDownload PDF (988K)
Special Topic:AMS 7
Report
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2012 Volume 37 Issue 6 Pages 297-303
Published: 2012
Released on J-STAGE: September 16, 2014
JOURNAL RESTRICTED ACCESSDownload PDF (767K)
Original Contribution
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Masako Miki, Yasuharu Yamada, Tadashi Inagaki, Syunsuke Tanie2012 Volume 37 Issue 6 Pages 304-311
Published: 2012
Released on J-STAGE: September 16, 2014
JOURNAL FREE ACCESSThe physical and gas transport properties of hyperbranched polyimide (HBPI)-silica hybrid membranes treated with carbon dioxide (CO2) gas were investigated and compared with those of linear-type polyimide-silica hybrid membranes to estimate the influence of the molecular structure and hybridization on the stability of gas transport property. For all of the membranes examined, there was no marked change in the FT/IR spectrum or the UV-VIS spectrum before and after CO2 treatment, indicating no influence on the polyimide molecular chain and the threedimensional Si-O-Si network themselves by the CO2 treatment. In HBPI-silica hybrid membranes, it was suggested that CO2 treatment did not cause deterioration of stability of gas transport property. The reason for this was that the restraints of the micro-Brownian motion or the densification of polyimide molecular chains and the stiffening of the three dimensional silica networks have been induced. In contrast, mild plasticization seems to have been caused in 6FDA-based linear-type polyimide-silica hybrid membranes. In addition, although CO2 treatment decreased both the gas permeability and the selectivity of non-6FDA-based polyimide membranes, it increased the selectivity of the 6FDA-based polyimide membranes.View full abstractDownload PDF (638K)
Products Spotlight
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Planar Cell Option for the Zetasizer Nano SeriesMiyuki Funato2012 Volume 37 Issue 6 Pages 312-314
Published: 2012
Released on J-STAGE: September 16, 2014
JOURNAL RESTRICTED ACCESSThe Zeta Potential of a coated membrane cannot be determined by measurement of the colloidal material used to prepare the coating. Direct measurement of the membrane Zeta Potential is necessary however conventional techniques used to measure the Zeta Potential of membranes are time consuming and difficult to use. To overcome this difficulty Malvern Instruments has developed a novel cell for the measurement of the Zeta Potential of planar surfaces (planar cell). The planar cell design is much simpler than existing designs, relatively easy to use after a minimum of instruction and is available as an option for the Zetasizer Nano series. In this article we will introduce the measurement principle and technology.View full abstractDownload PDF (674K)
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