The synergistic effect of synergists, MGK 264,Synepirin 500 and piperonyl butoxide, combined with eight pyrethroids were evaluated on the adult cat flea, Ctenocephalides felis, by using the film contact method. MGK 264 was the most effective. The mixtures of eight pyrethroids combined with MGK 264 at a ratio of 1 : 5 were estimated to be 4.88,8.39,4.71,8.11,4.50,5.88,8.84,and 2.50 times as toxic as d-allethrin, permethrin, phenothrin, cyphenothrin, prallethrin, d-resmethrin, cyfluthrin, and empenthrin alone, respectively. The synergistic effects of Synepirin 500 and piperonyl butoxide combined with pyrethroids were inferior to that of MGK 264. The effects of empenthrin, cyphenothrin, cyfluthrin and prallethrin increased proportionately with increase in combination ratio of MGK between 1 : 1.25 and 1 : 20.
View full abstract