Data on ventilatory function with particular reference to forced vital capacity (FVC), forced expired volume in one second (FEV
1), and FEV
1 expressed as percentage of FVC (FEV
1%FVC) were obtained in 1413 healthy Tanzanian school children aged between 8 and 18 years. All subjects were nonsmokers and had neither symptoms nor history of cardiopulmonary diseases. Subjects in this study were significantly smaller in stature (
P<0.05) and had smaller FVC and FEV
1 (
P<0.001) compared to values reported in children of comparable age and stature in the west. Lung volumes could best be described as a power function of standing height (
y=a.H
b). The power derived from ln FVC on ln H were 3.39 and 3.24 for boys and girls respectively, while the power derived from ln FEV
1, on ln H were 3.11 and 3.03 for boys and girls respectively. Constructed prediction formulae gave FEV
1 and FVC which showed good agreement with FEV
1 and FVC computed from prediction equations based on a similar mathematical model for black children in the Caribbean.
View full abstract