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Volume 27 (1981)
- Issue 6 Pages 541-
- Issue 5 Pages 410-
- Issue 4 Pages 321-
- Issue 3 Pages 229-
- Issue 2 Pages 121-
- Issue 1 Pages 1-
Predecessor
Volume 27, Issue 6
Displaying 1-5 of 5 articles from this issue
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Kenji Taki, Koji Murakami, Takae Kawamura, Mieko Takamura, Reiji Wakus ...1981 Volume 27 Issue 6 Pages 541-545
Published: 1981
Released on J-STAGE: March 12, 2010
JOURNAL FREE ACCESSChanges in RCA activity following Blood Transfusion has not been previously reported. The hormones thyroid, parathyroid and aldosterone which are present in blood, have been reported to affect RCA activity, though their effects in transfused blood have not as yet been reported on. The RCA concentration and activity of red blood cells was measured in vitro in artificially prepared blood samples, to mimic a transfusion. Blood samples from normal children and adults were studied. The following 4 compounded groups were prepared: Group A—child blood; Group B—child red blood cells and adult plasma; Group C—adult blood; Group D—adult red blood cells and child plasma. The compounded blood samples were tonometried with gases as present in alveolar air during incubated at 37°C for 1 hour. The RCA concentration and activity, electrolytes, Zn and 2, 3-DPG in the haemolysate prepared of each of the above 4 sample groups were measured. Also T3, T4 and aldosterone were estimated from the plasma samples of each of the 4 above mentioned groups. It was observed that child plasma inhibited the RCA activity of adult red blood cells and vice versa. The results obtained suggest that the changes in RCA activity of recipient red blood cells are possibly related to the hormones thyroid, parathyroid and aldosterone present in the donor's plasma. The changes in RCA activity in recipient red blood cells following ‘blood transfusion’ are recognized and described as a new finding.View full abstractDownload PDF (589K) -
Katsuhiro Fukutake, Michio Fujimaki, Shojiro Ikematsu, Masao Hada, Kat ...1981 Volume 27 Issue 6 Pages 546-558
Published: 1981
Released on J-STAGE: March 12, 2010
JOURNAL FREE ACCESSAn in vitro analysis and clinical experiences with FEIBA as an agent for bypassing therapy to hemophilic patients with inhibitors are performed and obtained the following results;
1. The time course of generation of Xa and IIa in plasma of hemophilia with or without inhibitors are measured by the use of chromogenic synthetic substrats, S-2222 and S-2238, after the addition of Ancrod in order to defibrinate the plasma. Although the generation of amydolytic activities in the cases with hemophilia decreases remarkably in comparision with normal plasma, the amydolytic activities can be normalized by the addition of FEIBA into the hemophilic plasma with inhibitor.
2. When the hemophilic patients with inhibitors are treated by the drip infusion of FEIBA, the clotting time of PTT are apparently shorten in parallel with the increase of Xa and IIa generations.
3. When antiserum of factor IX or factor VII is added into the mixture of FEIBA and phospholipids suspended in calcium solution, the inhibitory effect of anti-factor VII serum is more stronger than that of antifactor IX serum on the IIa generation and the former shows marked inhibitory action indicating dosedependent reaction. Therefore, it is suggested that factor VII in FEIBA might play an important role in the bypassing therapy.View full abstractDownload PDF (1626K) -
Kayoko Shimizu1981 Volume 27 Issue 6 Pages 559-565
Published: 1981
Released on J-STAGE: March 12, 2010
JOURNAL FREE ACCESSWe studied the function in vitro of human granulocytes. Human granulocytes were isolated from whole blood collected into acid-citrate-dextrose (ACD) and from the buffy coat of ACD-collected blood by dextran sedimentation. The whole blood is preserved in glass bottles and the buffy coat in plastic bags.
We measured viability, chemotaxis, phagocytosis-connected oxygen consumption and chemiluminescence in granulocytes isolated from blood by dextran sedimentation.
The data suggest the following: (1) in the all functions of granulocytes, the buffy coat preserved in plastic bags showed less changes than the whole blood in glass bottles. (2) on the effect of storage, these functions can not be kept for 2 days at 4°C in human granulocytes isolated from the buffy coat.
These studies suggest that storage of normal granulocytes used for transfusion should be limited to approximately 24 hours.View full abstractDownload PDF (857K) -
Yoshiki Mukumoto, Makoto Hashimoto, Kazuhiko Ito, Seizo Iwai1981 Volume 27 Issue 6 Pages 566-569
Published: 1981
Released on J-STAGE: March 12, 2010
JOURNAL FREE ACCESSThe registration system of patients for blood transfusion has been carried out for four years in Kobe University Hospital. Patients are registered in the Blood Transfusion Service immediately after admission to our hospital. The registered patient is serially numbered and examined for the blood type of ABO system and D antigen of Rh system and atypical antibodies.
The registration system has merits indicated below:
1. The registered number (numbers of one to four figures) is used in place of the name. The business in blood transfusion is simplified.
2. Compatible blood for patients with atypical antibodies can be selected in advance.
3. The blood type of ABO system and D antigen of a patient are doubly checked by a docter in charge and a technician in the Blood Transfusion Service. The blood types and the presence of atypical antibodies of the patient can be confirmed when blood is delivered from the Blood Transfusion Service.View full abstractDownload PDF (459K) -
1981 Volume 27 Issue 6 Pages 572-631
Published: 1981
Released on J-STAGE: March 12, 2010
JOURNAL FREE ACCESSDownload PDF (7025K)
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