Journal of the Japan Society of Blood Transfusion
Online ISSN : 1883-8383
Print ISSN : 0546-1448
ISSN-L : 0546-1448
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Volume 28, Issue 6
Displaying 1-3 of 3 articles from this issue
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  • TWO SUCCESSFUL CASES OF CRYOGLOBULINEMIA TREATED BY PLASMA EXCHANGE USING CRYOGLOBULIN-DEPLETED AUTOLOGOUS PLASMA
    Hitoshi Ohto, Yoichi Shibata, Makoto Uchikawa, Hiroshi Tohyama, Yasuno ...
    1982 Volume 28 Issue 6 Pages 495-503
    Published: 1982
    Released on J-STAGE: March 12, 2010
    DOIhttps://doi.org/10.3925/jjtc1958.28.495
    JOURNAL FREE ACCESS
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    Two patients of cryoglobulinemia associated with multiple myeloma were treated very effectively by plasma exchange using an IBM Model 2997 Blood Cell Separator.
    We used, as a replacement fluid in a subsequent plasma exchange, cryoglobulin-depleted autologous plasma by removing abnormal proteins after cold incubation. The patient's plasma was collected into 300-500ml transfer packs and replaced by equivalent volume of fresh frozen plasma at first. They were stored at 4°C or at -2°C during 14-21 days. Then the plasma was centrifuged at 4°C, 1600xG for 30 minutes. The supernatant in which cryoglobulin was removed could be used as a replacement fluid in the next plasma exchange.
    It is concluded that the advantages of autologous plasma exchange seem to be substantial: all risks of incompatibility or of alloimmunization, and of transmission of infectious diseases such as viral hepatitis, are completely avoided. In addition, the expensive cost of the replacement fluid can be saved markedly.
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  • TWO CASES OF AUTOIMMUNE HEMOLYTIC ANEMIA (AIHA) TRANSFUSED WITH RED BLOOD CELLS, AND INDICATION OF TRANSFUSION THERAPY FOR AIHA
    Fumio Komatsu, Keiichi Okamura, Hiroko Daidoji
    1982 Volume 28 Issue 6 Pages 504-511
    Published: 1982
    Released on J-STAGE: March 12, 2010
    DOIhttps://doi.org/10.3925/jjtc1958.28.504
    JOURNAL FREE ACCESS
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    Two cases of AIHA transfused with RBCs are described. These cases were in a particularly stormy episode, acute hemolytic crisis with reticulocytopenia in Case 1, and hemorrhagic distress in Case 2. In Case 2 the improvement was observed soon after transfusion, whereas in Case 1 the reaction with DIC-like symptom followed on the 10th day after administration of RBCs.
    As a general principle it is preferable to avoid blood transfusion in a patient with AIHA, because compatible blood cannot be obtained and transfusion reaction such as hemolysis or DIC may occurs. Occasionally however there are medical emergencies in which it is impossible to avoid transusion, and the indication of transfusion therapy for AIHA has been discussed.
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  • [title in Japanese]
    1982 Volume 28 Issue 6 Pages 514-588
    Published: 1982
    Released on J-STAGE: March 12, 2010
    DOIhttps://doi.org/10.3925/jjtc1958.28.514
    JOURNAL FREE ACCESS
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