Oxygen transport function of preserved blood decreases as a function of storage period. For quality control of preserved erythrocytes, any quantitative estimation is to be established. However, no systemic evaluation of the cell function has been extablished. We proposed here an index, transfusion index, as an indicator for quantitative estimation of the cell function.
Transfusion index of the cells is a product of their oxygen delivery capacity and their posttransfusion survival. The transfusion index of stored blood drastically decreased when red cells were stored for more than two weeks in liquid preservatives at 4°C, indicating that red cells stored for more than two weeks are not adequate to the transfusion. Red cell oxygen delivery capacity closely related to the cell 2, 3-DPG concentration and the transfusion index could be raised by increasing 2, 3-DPG in the cells.

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The abnormalities of clinical labolatory tests were investigated among 17, 908 blood donors who came to the Department of Blood Transfusion, Nihon University Itabashi Hospital during the period from April 1, 1980 through March 31, 1983.
The first check-up showed that abnormal rates of GOT and GPT activities over 40 mIU were 5.0% and that abnormal rate of GPT alone was 5.1 times more than that of GOT alone. Moreover, 10.5% of 270HBs antigen carriers had abnormal GOT and GPT activities.
Of 102 patients with abnormal transaminase activities, clinical diagnosis in the secondary check-up included 65 patients (63.7%) with fatty liver associated with obesity and chronic alcoholic intake, 9 patients (8.8%) with chronic hepatitis and the remaining were required further examination for final diagnosis.
These results suggest that the occurrence of post-transfusion non-A non-B hepatitis is not always associated with blood from about two third of apparently healthy donors with abnormal transaminase activities, because most of them have metabolic disoder of the liver, not infectious disease.

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On the basis of the in vitro stability of factor VIII concentrate at room temperature, continuous intravenous infusion of the remedey could be utilized as a hemostatic management for a major surgey in hemophilia A. One hour prior to the amputation of the left femule of the patient, 55u/kg of Hemofil H^® as a bolus pretreatment and thereafter continuous infusion by quantitative pump with 2.7u/kg/hr of Hemofil H^® for 3 days, 2.2u/kg/hr for next 5 days, 1.6u/kg/hr for the third period of 6 days, and 0.8u/kg/hr for last period of 4 days were followed. Consequently it was able to stabilize the hemostatic level of plasma VIII:C with the preparation, of which amount was less than that of previous cases with major surgical operations managed by bolus infusions of the similar preparation.
Thus, this continuous infusion method applied on major surgery of hemophiliacs might be recommended as a thrapeutic way being safer and more economic than the conventional method, because no excess amount of factor VIII concentrate are infused.

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A patient with an intracranial arteriovenous malformation was a 18-year-old Japanese male and was transfused with compatible 134 units of various kind of the blood preparation during the operational extraction of the malformation. Anti-f and anti-S antibodies were detected in his serum 5 months after the operation. Both antibody titers measused by indirect antiglobulin test were 128. Anti-f in his serum agglutinated 9.0% of ABO matched and D antigen positive red cells. The Rh phenotypes of agglutinated red cells were CcDee, ccDEe, and CcDEe. These red cells probably have ce haplotype. To our knowledge, this is the first reported example of anti-f found in the Japanese.

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