Journal of the Japan Society of Blood Transfusion
Online ISSN : 1883-8383
Print ISSN : 0546-1448
ISSN-L : 0546-1448
Volume 19, Issue 3
Displaying 1-4 of 4 articles from this issue
  • K. HIGUCHI, E. SHIINA, K. TOMITA, Y. MORIKAWA, N. NARAHARA, M. MOTEGI, ...
    1973 Volume 19 Issue 3 Pages 67-81
    Published: 1973
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    This study was designed to determine the clinical response to Hydroxyethyl Starch solution as a plasma substitutes.
    The results indicate that the HES solution was well tolerated in almost all patients, particularly in geriatric surgery.
    1. From five hundred to 1500ml. of HES solution were administered intravenously to 12 preoperative patients including four cases of over 60 years old. Decrease of Ht., Hb., RBC, and WBC, which were supposed to be due to hemodilution, were observed. Increase of serum albumin and decrease of serum globulin besides decrease of serum protein were observed in all cases. Being yet not significant, it was supposed that HES solution might improve liver and kidney function. Arterial pH remained normal. More over, no side effect was observed.
    2. From five hundred to 2000ml. of HES solution were administered intravenously during surgery under general anesthesia to 45 patients including 11 of over 60 years old. Blood loss during surgery remained non-significant with that of control group. Three of 45 cases showed less 30% decrease of blood pressure during surgery, and others remained favorable level after surgery as well. Central venous pressure was slightly increased in a few cases. No circulatory and respiratory trouble was encountered even in an emergent and aged patient during surgery. Urinary output in postoperative period was favorable and all cases showed uneventful postoperative course.
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  • Yasuhiro KAZAHAYA, Ryoichi NAITO
    1973 Volume 19 Issue 3 Pages 82-88
    Published: 1973
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    Human plasma fraction derivatives, Plasmanate (5% plasma protein solution) and globulin (15%), were made from 2 kinds of human plasma pools proven either positive or negative of Au-antigen by immunoelectrosynelesis technic (IES). Both plasma pools and their products were quantitatively measured for Au-antigen and -antibody by Solid Phase Radioimmunoassay.
    While Au-antigen positive plasma manifested 104 of Au-antigen concentration, derived Plasmanate and ISG preparations showed the titer of 103 and 101 respectively. While Au-antigen negative plasma manifested 101 of Au-antigen, derived Plasmanate and ISG showed the titer smaller than 10°.
    There was no difference in the antibody-binding ability of Au-antigen present in Plasmanate (Au-antigen positive origin) before and after heat-treatment at 60°C for 10 hours. Au-antibody was not found in Plasmanate. Au-antibody in the globulin preparation from Au-antigen negative plasma was found higher than that from Au-antigen positive plasma.
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  • Ryoji ISHII, Takemichi HIRANO
    1973 Volume 19 Issue 3 Pages 89-93
    Published: 1973
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    The distribution of Australia antigen (Au-ag) and the antibody towards the antigen (Au-ab) in family donors in Blood Transfusion Center, School of Medicine, Keio University, was studied by using Solid Phase radioimmunoassay technique.
    Au-ag was detected in 5.9% of the tested donors, and Au-ab was detected in 23%.
    No relationship among the value estimated of Au-ag, SGOT and SGPT in donors could be found.
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  • 1973 Volume 19 Issue 3 Pages 94-106
    Published: 1973
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
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