北関東医学
Online ISSN : 1883-6135
Print ISSN : 0023-1908
ISSN-L : 0023-1908
23 巻, 5 号
選択された号の論文の5件中1~5を表示しています
  • 山添 三郎
    1973 年 23 巻 5 号 p. 327-334
    発行日: 1973/09/01
    公開日: 2010/02/09
    ジャーナル フリー
  • (1)リビドマイシンの抗菌作用
    稲福 全昌
    1973 年 23 巻 5 号 p. 335-341
    発行日: 1973/09/01
    公開日: 2009/10/15
    ジャーナル フリー
    Many papers have been presented on the enzymatic inactivation of the aminoglycosidic antibiotics by cell-free extracts obtained from drug-resistant strains of bacteria isolated from clinical specimens. Kanamycin is inactivated by two mechanisms responsible for the formation of 6-N-acetyl-kanamycin and 3'-phosphorylkanamycin. Similarly, streptomycin is inactivated by the formation of adenylylstreptomycin and phosphorylstreptomycin. These facts indicate that three mechanisms, i.e., phosphorylation, acetylation and adenylylation, involve in the inactivation of aminoglycoside antibiotics. It was reported previously that lividomycin, a new aminoglycosidic pentasaccharide antibiotic containing 2-deoxystreptamine, lacks the hydroxyl group at the C-3 position of the D-aminoglucose moiety and is not inactivated by a kanamycin-phosphorylating enzyme. This paper deals with the studies of anti-bacterial activity of lividomycin (LV) toward many strains of bacteria isolated from clinical specimens. The results are summarized as follows :
    1) There are two types of LV-resistant strains. One group is capable of inactivating LV by phosphorylation and another group can not inactivate the drug.
    2) The inactivated product is a monophosphorylated LV.
    3) Chemical studies disclosed that the hydroxyl group at the 5″-position of the ribose moiety is phosphorylated.
  • 樋口 次男, 真下 延男, 小内 正幸
    1973 年 23 巻 5 号 p. 343-353
    発行日: 1973/09/01
    公開日: 2009/10/15
    ジャーナル フリー
    We in our department have been adopting the endoscopic diagnosis with duodenal fiberscope since 1969 and have reported here our cases with this technique.
    We had 75 cases to be examined. The classification of the diseases determined by the final diagnosis consisted of 7 cases without abnormalities, 30 cases with duodenal ulcer, 27 cases with the scar of duodenal ulcer, 3 cases with duodenal tumor, 2 cases with the early stage of stomach cancer and other 6 cases. In addition, we had 20 cases with the retrograde pancreato-cholangiography. It would be interesting to describe as follows :
    1) The rate of success in the retrograde pancraeto-cholangiography : 85%
    2) Complications : The titers of serum and urine amylase were increased temporarily in 2 of 18 cases and returned to the normal level without subsequent cmplications.
    It is now hopeful from the above observations that the technique of the endoscopic diagnosis with duodenal fiberscope seems to be useful further with safety, for the diagnosis, particularly the pancreas diseases, although the rate of success appears to be somewhat lower.
  • (3) 新生児回腸穿孔
    松山 四郎, 長島 起久雄, 原田 哲夫
    1973 年 23 巻 5 号 p. 355-357
    発行日: 1973/09/01
    公開日: 2009/10/15
    ジャーナル フリー
    A case of diastatic perforation of the ileum in a three-day-old female infant was presented. She was born on May 4, 1972 and appeared normal at birth. She began vomiting at 6 hours of age. Abdominal distention and bilious vomiting had developed in the patient by 15 hours of age. The abdominal scout film made on admission to the Haramachi Red Cross Hospital, revealed distended loops of small bowel with air-fluid levels, and a small amount of free intraperitoneal air was already seen below the diaphragm (Fig. 1). Gastrografin enema showed a microcolon and the contour of the small bowel presumably floating on the peritoneal fluid, was visible (Fig. 2).
    Laparotomy was performed 46 hours of age at the Gunma University Hospital. Surgery disclosed diaphragmatic obstruction of the distal ileum and a perforation of dilated ileum proximal to the atresia. Approximately 17 cm of the ileum including the atretic segment was resected and an end-to-end anastomosis was performed. Her postoperative course was uneventful and she was discharged on 17th postoperative day.
  • 1973 年 23 巻 5 号 p. 371-392
    発行日: 1973/09/01
    公開日: 2009/10/15
    ジャーナル フリー
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