Shichijo's reaction, which is highly positive in stomach cancer, will be useful as supplementary diagnostic method in reading gastrophotograph, especially in differentiation of stomach cancer from the related diseases. On this assumption, relation between gastrocamera pictures of various stomach diseases and Shichijo' s reaction was investigated, and some new findings were obtained.
1) Out of 57 cases, diagnosed as stomach cancer by gastrocamera study, 51 cases (89.51%) are considered to be possible positive definitely positive reaction and intermediate reaction in Shichijo' s reaction.
Of these 51 cases, 43 had definitely positive reaction and the others the intermediate. The high incidence of the possible positivity supports the concept that this reaction is very useful for making diagnosis of stomach cancer.
2) Out of 516 cases with stomach diseases other than cancer, 56 (10.9%) showed possible positive reaction, However, the definitely positive reaction was found only in 7 cases, and the majority showed the intermediate reaction.
3) Stomach cancers were divided into the early and the high infiltration group according to the grade of in filtration. and Shichijo's reaction was shown possible positive at equal rate in the both groups. In this way, the reaction was confirmed as excellent supplementary method for the diagnosis of early stomach cancer.
4) Benign stomach ulcer was classified into various stages, and Shichijo' s reaction in each was examined. The possible positivity rate was relatively high in the convalescent stage, On account of this, the author pointed out necessity to pay particular attention to the above fact in the diagnosis of stomach ulcer with cicatrical appearance.
5) Shichijo's reaction was performed with 49 cases of stomach ulcer, suspected of malignancy by gastrocamera picture but pathohistologically indicated to be benign, and 14 cases with malignant ulcer. All the former were negative, while all the latter showed the possible positive reaction. Shichijo' s reaction was thus found useful as supplementary method also in differetiating malignant from benign stomach ulcer by means of gastrocamera picture.
6) Malignant stomach ulcer was divided into the early and the highly infiltrated cancer according to the grade of infiltration, and Shichijo' s reaction was performed with the result it was possible positive nearly at equal rate in the both groups. It was therefore emphasized that the reaction was sufficiently useful for the diagnosis of early stomgch cancer.
7) Out of 324 cases of chronic gastritis, with whom Shichijo' s reaction was performed 44 (13.6%) showed the possible positive reaction. However, the definitely positive reaction was found only in 4 cases, and the majority showed the intermediate reaction. Therefore Shichijo's reaction was considered useful as supplementary method in differentiating stomach cancer from chronic gastritis by gastrocamera picture.
8) Gastrocamera pictures of chronic gastritis were analyzed, and Shichijo' s reaction in patients of this disease was investigated. And it was found that the possible positivity rate tended to be rather higher among those with atrophic gastritis, especially with high metaplasia. The author considers this worth to notice, since there are many reports which stress the presence of metaplasia in precancer state.
9) It is sometimes difficult to differentiate superficial and hyperplastic gastritis from stomach cancer so far as the gastrccamera is used as the diagnostic means. However, this difficulty can be largely eliminated by taking Shichijo' s reaction into account.

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1) Treatment with Le^a enzyme preparation from Bac. cereus Le^a destroys Le^a activity of O Le(a+b-) erythrocytes and glycolipid, and liberates fucose and galactose as monosaccharides.
2) The enzymatic treatment of O Le(a-b+) erythrocytes and glycolipid results the liberation of galactose which is unrelated to the end unit of the blood group determinant.
3) On the basis of the number of moleculs of the fucose, Le^a combining sites on each O Le(a+b-) red cell are estimated to be 955, 000.

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This case of cancer of the stomach was reported because of unusual multiple metastases in the spinal and cranial nerve-roots. A 48 aged woman was admitted with chief complaints of disturbance in gait, intermittent attacks of faintness and headach. During the course she had had no uspect of the stomach and bowels, and was diagnosed as having neurosyphilis on the ground of signs of progressive cerebrospinal irritations and positive serologic test for syphilis in the spinal fluid. She died about 3 months after the onset of symptoms.
Necropsy disclosed diffuse thickening of the whole stomach wall with formation of superficial ulceration and small tumor nodule. Microscopiscally the tumor tissue was made up of diffusely infiltrating cells mainly of signet-ring-cell structure (Carcinoma simplex mucocellulare). By the way of lymphatic and transcoelomic dissemination metastases were formed in the retroperitoneal lymphnodules and pelvic organs. Tumor cells made also a prominent invasion upon the spinal and cranial nerve-roots, as well as upon the leptomeninges. Examinations of the peripheral nerves disclosed diffusely infiltrating tumor cells along the nerve sheaths. Their proximal growth, however, were found restained by the terminal zone of the spinal horn.
It seems reasonable to conclude that malignant tumor cells may reach the spinal cavity through the rout along the perineural lymphspaces rather than by the blood-stream.

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This report is concerned with a 2-months-old male infant of congenital heart disease with chief clinical signs of progressive cyanosis. Necropsy disclosed a complex of anomalies in the heart embracing pulmonary atresia, interventricular high septal defect, interatrial septal defect, deviation in the origin of the aorta to the left, and hypertrophy of the right ventricle. The lungs were found to receive the blood supply through patent ductus arteriosus. The pulmonary veins were found emptying not into the left atrium but into the superior vena cava. The malformations in the heart was associated with abnormalities in the other organs. The spleen was absent and abnormal lobulations were found in the lungs.

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This report deals with a male patient of 28 years, suspected of the metastatic tumor formation of stomach carcinoma to the lungs.
On section, a fist-sized primary tumor was revealed in the mediastinum and metastatic tumors were recognized in the lungs, lymph nodes of pulmonary hilus, kidneys, ileum and cerebellum. Gynecomastia was noticed besides the tumor formation.
Histologically, mediastinal tumnr was typical chorioepithlioma and metastatic tumors showed entirely similar pictures.
In the testis and other genital organs or bladder, there is no tumor or scar, haemorrhge and necrotic areas which were thought to be the vestige of the involution of the primary tumors.
On account of the above mentioned histological and gross findings, it is considered that this case was chorioepithelioma in the male originating in the mediastinum.

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