Neurologia medico-chirurgica
Online ISSN : 1349-8029
Print ISSN : 0470-8105
ISSN-L : 0470-8105
Volume 32, Issue 11
Displaying 1-10 of 10 articles from this issue
  • Hiroshi TENJIN, Satoshi UEDA, Norihiko MIZUKAWA, Yoshio IMAHORI, Akihi ...
    1992 Volume 32 Issue 11 Pages 805-810
    Published: 1992
    Released on J-STAGE: June 20, 2006
    JOURNAL FREE ACCESS
    Specific hemodynamic changes in acute ischemia were investigated using a middle cerebral artery occlusion primate model and positron emission tomography. The cerebral blood flow (CBF), cerebral blood volume, oxygen extraction fraction (OEF), and cerebral metabolic rate for oxygen were measured 1, 3, and 9 hours after occlusion. OEF showed an increase in ischemic areas, and especially where CBF was below 18 ml/100 gm/min 1 hour after occlusion the OEF increased significantly (0.69 ± 0.20, p < 0.05). Nine hours after occlusion, the OEF values were lower compared to those 1 and 3 hours after occlusion. Areas where CBF ranged from 18 to 31 ml/100 gm/min showed an increase in OEF at all times (p < 0.05). Clearly, OEF changes remarkably in the acute stage.
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  • Jun-ichiro ASAI, Yoshiharu FUKUSHIMA, Yoshiaki MAKINO
    1992 Volume 32 Issue 11 Pages 811-817
    Published: 1992
    Released on J-STAGE: June 20, 2006
    JOURNAL FREE ACCESS
    Proteins from 21 cerebrospinal fluid (CSF) samples (14 derived from neurological cases and 7 from normal individuals) and 15 serum samples (11 from neurological cases and 4 from normal individuals) were analyzed by two-dimensional electrophoresis. Protein mapping revealed a very acidic protein (Ac-P) at about pH 3.5 in the 71% of CSF samples from neurological cases. However, no serum sample contained Ac-P. Ac-P was isolated and purified, and determined to be a glycoprotein containing a large amount of carbohydrate, with molecular weight 42, 000 and isoelectric point 2.7-3.3. The amino acid composition of Ac-P was consistent with α1-acid glycoprotein (AGP), and Ac-P was responsive to a commercial anti-AGP antiserum in the radial immunodiffusion test.
     The known polymorphism of AGP suggests some differences in physicochemical properties such as molecular weight and isoelectric point between AGP in serum and in CSF. Quantitative analysis of Ac-P (AGP) and total protein levels in CSF showed a partial interdependence. Ac-P may be a useful marker for detecting a pathological conditions of the central nervous system.
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  • Toru FUSEJIMA, Ryuichi TANAKA, Norio TAKEDA, Hiroaki HONDO, Kiyoshi ON ...
    1992 Volume 32 Issue 11 Pages 818-823
    Published: 1992
    Released on J-STAGE: June 20, 2006
    JOURNAL FREE ACCESS
    A retrospective analysis of 32 patients with primary malignant lymphoma of the central nervous system (CNS) diagnosed between 1976 and 1989 investigated treatment results and recurrence patterns. All patients showed either complete or partial regression of the tumor after initial treatment, mainly radiation therapy with adjuvant chemotherapy. The mean dose of whole-brain irradiation was 40.9 Gy and that of booster was 14.4 Gy. Most patients had tumor recurrence. The median time to recurrence from completion of the treatment was 5 months. The 1- and 5-year survival rates were 50.0 and 17.7%, respectively, and the overall median survival time was 11 months. Most tumors had multiple recurrences at the primary site and other regions of the CNS, and tended to recur in the periventricular region and the cerebrospinal fluid space. Spinal metastasis occurred in five cases. The importance of good control of the primary lesion and active maintenance therapy for the whole CNS is emphasized.
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  • Hisashi KOGA, Jiro MUKAWA, Munetomo NAKATA, Osamu SAKUTA, Yasushi HIGA
    1992 Volume 32 Issue 11 Pages 824-828
    Published: 1992
    Released on J-STAGE: June 20, 2006
    JOURNAL FREE ACCESS
    To identify the causes of ventricular shunt catheter retention, 42 shunt removals in 28 patients in our neurosurgical clinic from 1982 to 1991 were analyzed. The mean patient age was 13.8 years (2 mos-78 yrs), and mean shunt duration was 20.1 months (0.5-94 mos). There were nine retained ventricular catheters, including five with obstruction of the ventricular catheter. Shunt duration was significantly longer compared with the unretained group. Three retained ventricular catheters were stained by HE for histological examination. Light microscopy showed the inner lumen of catheters filled with granulomatous connective tissue and reactive glial tissue, and giant cell reaction to silicone material. Scanning electron microscopy of two catheters found peeling on the inner surface of the catheter, evidence of aging of the material. Granulomatous connective tissue and glial tissue reaction to aged silicone are suggested as the cause of catheter retention.
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  • Masaharu ICHIKAWA, Yukio SHIMIZU, Manabu SATO, Kiyoharu IMATAKA, Atsus ...
    1992 Volume 32 Issue 11 Pages 829-833
    Published: 1992
    Released on J-STAGE: June 20, 2006
    JOURNAL FREE ACCESS
    A rare case of abscess within a glioblastoma with an unusual presentation occurred in a 46-year-old female who developed right hemiparesis and seizure. Computed tomography and magnetic resonance imaging demonstrated hemorrhage which mimicked hemorrhagic infarction. However, the lesions developed ring enhancement. Aspiration showed one to be an abscess, which collapsed by drainage but later re-expanded. The mass was removed, and histological examination revealed glioblastoma.
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  • —A Case with Recurrent Intracerebral Hemorrhage—
    Kinzo IWATA, Norio MISU, Yoshiharu NARA
    1992 Volume 32 Issue 11 Pages 834-838
    Published: 1992
    Released on J-STAGE: June 20, 2006
    JOURNAL FREE ACCESS
    Granulomatous angiitis of the central nervous system occurred in a 43-year-old male presenting with recurrent intracerebral hemorrhage confirmed by computed tomography. A surgical specimen obtained at hematoma removal revealed granulomatous angiitis. Systemic investigation found no underlying cause for the hemorrhage. Although the incidence is very low, this condition should be considered in cases of recurrent intracerebral hemorrhage with unknown cause. When surgery is indicated, biopsy of the brain and leptomeninges should be obtained, because involvement of the leptomeninges has occurred in virtually all autopsy cases.
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  • Hirofumi OYAMA, Satoshi NODA, Makoto NEGORO, Takehisa KINOMOTO, Shiger ...
    1992 Volume 32 Issue 11 Pages 839-841
    Published: 1992
    Released on J-STAGE: June 20, 2006
    JOURNAL FREE ACCESS
    A 53-year-old female was admitted with apathy, left sensory and motor disturbance, left homonymous hemianopsia, and dressing apraxia. Computed tomography and magnetic resonance imaging showed a huge mass markedly enhanced in and around the right trigone. Cerebral angiography revealed rich vascularity of the tumor mainly fed by the right anterior choroidal artery. The feeding vessel was embolized with microfibrillar collagen after superselective catheterization. Seven days later, the tumor was totally removed with low blood loss. The histological diagnosis was fibroblastic meningioma. She was discharged without neurological deficit, except for left homonymous hemianopsia.
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  • Kenji WAKUI, Yukihiro KAMIJO, Kyoji SEGUCHI, Teruo SAKAI
    1992 Volume 32 Issue 11 Pages 842-845
    Published: 1992
    Released on J-STAGE: June 20, 2006
    JOURNAL FREE ACCESS
    A 54-year-old female presented with subarachnoid hemorrhage due to rupture of a small middle cerebral artery aneurysm, found to be thrombosed at surgery and not visualized on the preoperative angiograms. One major branch of the middle cerebral artery was found to be occluded near the trifurcation. The lumen of the branch proximal to the occlusion had appeared as the aneurysmal opacification on the preoperative angiograms.
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  • Kyoji SAKAI, Shoji ASARI, Mutsuo FUJISAWA, Ryosuke KATAGI
    1992 Volume 32 Issue 11 Pages 846-850
    Published: 1992
    Released on J-STAGE: June 20, 2006
    JOURNAL FREE ACCESS
    A 64-year-old male presenting with subarachnoid hemorrhage had a saccular aneurysm arising from the anomalous anterior cerebral artery. The aneurysm was located on the curved mid-portion of the anomalous artery and extended underneath the right optic nerve. The aneurysm was clipped without unroofing the right optic canal. Postoperatively, he suffered from temporary mild deterioration of the right visual acuity. Hemodynamic stress may be important in the development of such aneurysms.
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  • Hidenobu OCHIAI, Shinichi NAKANO, Tomokazu GOYA, Shinichiro WAKISAKA, ...
    1992 Volume 32 Issue 11 Pages 851-853
    Published: 1992
    Released on J-STAGE: June 20, 2006
    JOURNAL FREE ACCESS
    A rare case of pituitary metastasis of thyroid follicular adenocarcinoma occurred in a 62-year-old female manifesting as left retro-orbital pain and diplopia. Computed tomography and magnetic resonance imaging revealed a tumor in the pituitary fossa extending to the left cavernous sinus, sphenoid sinus, and prepontine cistern, destroying the upper portion of the clivus. An asymptomatic thyroid mass, probably malignant, was also found. She also had an incidental small meningioma in the posterior fossa. The pituitary tumor was partially removed, and the thyroid and posterior fossa tumors were totally removed in two operations. Both pituitary and thyroid tumors were verified to be follicular adenocarcinoma. Postoperatively, she developed panhypopituitarism for which cortisol and thyroxine replacement therapy was necessary. Three years after first therapy, she was alive but her symptoms did not improve.
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