Neurologia medico-chirurgica
Online ISSN : 1349-8029
Print ISSN : 0470-8105
ISSN-L : 0470-8105
Volume 36, Issue 4
Displaying 1-10 of 10 articles from this issue
  • Go DAITA, Yukichi YONEMASU
    1996 Volume 36 Issue 4 Pages 211-214
    Published: 1996
    Released on J-STAGE: April 10, 2006
    JOURNAL FREE ACCESS
    The relationship between invasiveness and proliferative potential was studied in 31 cases of pituitary adenomas. The invasiveness was determined by histological examination of sellar floor dura resected during transsphenoidal surgery. The proliferative potential of adenoma specimens was examined immunohistochemically using monoclonal antibody (MIB-1). There were 11 adenomas with histologically verified dural invasion out of 31 cases. These adenomas had a higher MIB-1-positive ratio than adenomas without dural invasion (p <0.05). Pituitary adenomas with a high proliferative potential tend to be invasive.
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  • Slobodan MARINKOVIC, Hirohiko GIBO, Ivana NIKODIJEVIC
    1996 Volume 36 Issue 4 Pages 215-219
    Published: 1996
    Released on J-STAGE: April 10, 2006
    JOURNAL FREE ACCESS
    The trigeminocerebellar artery was found on the left side in one of 22 brainstems, with the vasculature injected with India ink or methylmethacrylate. The trigeminocerebellar artery, which measured 910, um in diameter, arose from the basilar artery. The artery was divided into the pontine, trigeminal, cerebellopontine, and cerebellar segments. The artery supplied the anterolateral and lateral part of the pons, the trigeminal nerve root, the middle cerebellar peduncle, and most of the petrosal surface of the cerebellar hemisphere. Although relatively rare, the trigeminocerebellar artery may cause trigeminal neuralgia. Occlusion of this artery would cause a syndrome similar to the lateral midpontine syndrome. The trigeminocerebellar artery could be misinterpreted on angiograms as the anterior inferior cerebellar artery with a high origin from the basilar artery.
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  • Masahiro KURISAKA, Koreaki MORI
    1996 Volume 36 Issue 4 Pages 220-223
    Published: 1996
    Released on J-STAGE: April 10, 2006
    JOURNAL FREE ACCESS
    Superoxide dismutase (SOD) expression in tumor tissues was investigated in 10 cases of medulloblastoma by immunohistochemistry, using a monoclonal antibody against human copper and zinc-superoxide dismutase. Abundant SOD was expressed in tumors from patients with poor outcomes and little SOD in patients with good outcomes. These results suggest that resistance to adjuvant therapy depends on the amount of SOD in tumor tissues. The effects of adjuvant therapies for medulloblastomas depend on the production of free oxygen radicals, so if tumor cells contain a free radical scavenger such as SOD, the effects of adjuvant therapy may be reduced. Measurement of SOD in tumor tissues may be useful as a prognostic indicator for medulloblastoma.
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  • Motohiro MORIOKA, Akimasa YOSHIDA, Makoto YOSHIKAWA, Yukitaka USHIO
    1996 Volume 36 Issue 4 Pages 224-228
    Published: 1996
    Released on J-STAGE: April 10, 2006
    JOURNAL FREE ACCESS
    A 26-year-old male presented with transient alpha coma following minor head trauma after a traffic accident. His consciousness disturbance suddenly recovered 3.5 hours later. He had not suffered cardiac arrest before admission, nor was taking any drugs. Magnetic resonance (MR) angiography 6.5 hours after consciousness recovery disclosed persistent primitive trigeminal artery (PTA) with minor segmental narrowings. Three months later, MR angiography revealed that both the PTA and the distal basilar artery were slightly diated without evidence of narrowing. Conventional angiography and single photon emission computed tomography revealed that the distal basilar artery was supplied mainly by the PTA. Transient circulatory disturbance due to traumatic angiospasm of the PTA may have caused hypoperfusion of the upper brainstem in this patient.
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  • Miki FUJIMURA, Hirobumi SEKI, Takayuki SUGAWARA, Nobukazu TOMICHI, Tat ...
    1996 Volume 36 Issue 4 Pages 229-233
    Published: 1996
    Released on J-STAGE: April 10, 2006
    JOURNAL FREE ACCESS
    A 69-year-old female presented with a ruptured aneurysm at the distal tip of a fenestrated anomalous artery which originated in the ophthalmic segment of the internal carotid artery (ICA), passed between the optic nerves, ascended along the midline, and formed the fenestration before dividing into the bilateral pericallosal arteries. The anomalous artery manifested as subarachnoid hemorrhage. Four days later, she died from severe pulmonary edema. The angiographic finding was confirmed by postmortem examination. Numerous perforating vessels from the anomalous artery and the distal ICA supplied the optic nerves and chiasm. This finding supports the idea that this anomalous vessel may be an extreme developmental variation of the prechiasmal arterial plexus.
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  • Yutaka HONMA, Seigo NAGAO
    1996 Volume 36 Issue 4 Pages 234-236
    Published: 1996
    Released on J-STAGE: April 10, 2006
    JOURNAL FREE ACCESS
    A 68-year-old female presented with recurrent transient global amnesia due to hemorrhagic prolactinproducing pituitary adenoma. Magnetic resonance imaging clearly revealed the anatomical relationship between the hematoma, within the parasellar tumor, and the compressed medial temporal lobe of the right (non-dominant) hemisphere. Within 4 weeks after the start of bromocriptin administration, the adenoma had markedly regressed and the affected temporal lobe was decompressed. She has experienced no further episode of transient global amnesia. Magnetic resonance imaging is recommended to detect latent organic lesions responsible for transient global amnesia, although the disorder is considered to be benign and of functional origin.
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  • Eiji MORIYAMA, Yuzo MATSUMOTO, Toshinari MEGURO, Shohei MANO
    1996 Volume 36 Issue 4 Pages 237-240
    Published: 1996
    Released on J-STAGE: April 10, 2006
    JOURNAL FREE ACCESS
    A 75-year-old female presented with a suprasellar granular cell tumor. Computed tomography (CT) revealed a high dense suprasellar mass with strong postcontrast enhancement. Magnetic resonance imaging showed a round suprasellar mass, which was hyperintense on the T1-weighted images with nonhomogeneous enhancement after the administration of gadolinium-diethylenetriaminepenta-acetic acid, and hypointense on the T2-weighted images. Cerebral angiography demonstrated no abnormal findings. The tumor was partially removed via a right frontotemporal craniotomy. The histological diagnosis was suprasellar granular cell tumor. Her postoperative course was uneventful other than mild and transient diabetes insipidus. She has remained asymptomatic without CT evidence of tumor regrowth for 20 months after the surgery. Immunohistochemical studies showed positive reaction for S-100 protein in the tumor cell nuclei, but no reaction for glial fibrillary acidic protein, neurofilament protein, Leu-7, oxytocin, β-endorphin, adrenocorticotropic hormone, and vimentin. This case provides additional evidence for the astrocytic origin of suprasellar granular cell tumor.
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  • Masaaki YAMAMOTO, Shinji HAGIWARA, Mitsunobu IDE, Minoru JIMBO, Tatsuo ...
    1996 Volume 36 Issue 4 Pages 241-245
    Published: 1996
    Released on J-STAGE: April 10, 2006
    JOURNAL FREE ACCESS
    A 54-year-old female presented with a rapidly growing acoustic neurinoma. The tumor doubling time was 216 days or less before surgery and staining indexes for proliferating cell nuclear antigen (PCNA) and MIB-1 were relatively high (4.1% and 2.1%, respectively). The tumor was partially removed, but regrowth was detected with a tumor doubling time of 205 days. She underwent gamma knife radiosurgery for the residual tumor. The periphery of the tumor was irradiated with a dose of 15 Gy. Magnetic resonance imaging 30 months later demonstrated significant tumor shrinkage. The tumor half time following irradiation was determined to be 401 days. Neither surgery nor radiosurgery produced any additional neurological deficit or complications. Gamma knife radiosurgery can control neurinoma growth even when the tumor shows rapid growth and a relatively high growth fraction indicated by high staining indexes for PCNA or MIB-1.
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  • Nobuo HIRANO, Akira SASAKI, Takashi WATANABE, Tomokatsu HORI, Yasushi ...
    1996 Volume 36 Issue 4 Pages 246-250
    Published: 1996
    Released on J-STAGE: April 10, 2006
    JOURNAL FREE ACCESS
    A 58-year-old male presented with malignant fibrous histiocytoma originating from the lateral wall of the orbit, manifesting as left exophthalmos and diplopia on left lateral gaze. Magnetic resonance (MR) imaging demonstrated the tumor extending into the left orbit and under the temporalis muscle. The tumor was isointense with muscle on T1-weighted MR images and was surrounded by a low-intensity rim, which was proved to be the capsule after histological examination. The tumor was completely removed after detaching the lateral orbital rim and zygomatic arch using the dismasking flap method. He underwent one course of CYVADIC chemotherapy and has demonstrated no recurrence for 1 year and 6 months postoperatively.
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  • Yoshio NAKAGAWA, Kenzo SUZUKI, Atsushi TATEBE, Hiromu ANDACHI
    1996 Volume 36 Issue 4 Pages 251-254
    Published: 1996
    Released on J-STAGE: April 10, 2006
    JOURNAL FREE ACCESS
    A 63-year-old male presented with a rare epithelial cyst in the left cerebellopontine angle manifesting as left facial nerve paresis and left cerebellar signs. Computed tomography revealed a well-defined cystic mass of homogeneous low density with no enhancement. Magnetic resonance imaging also demonstrated a cystic mass appearing as low intensity on T1-weighted images and high intensity on T2-weighted images. The cyst content was clear fluid. The cyst wall consisted of nonciliated, columnar epithelial cells, showing a pseudostratified arrangement in focal areas. Positive staining by periodic acid-Schiff, Alcian blue, and carcinoembryonic antigen suggested that the cyst was an enterogenous cyst of endodermal origin. Cysts in this location often cause cranial nerve impairment, but the symptoms are usually resolved by surgical treatment.
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