Neurologia medico-chirurgica
Online ISSN : 1349-8029
Print ISSN : 0470-8105
ISSN-L : 0470-8105
Volume 26, Issue 7
Displaying 1-11 of 11 articles from this issue
  • Shunji NISHIO, Hiroto EGAMI, Masashi FUKUI, Katsutoshi KITAMURA, Hirok ...
    1986 Volume 26 Issue 7 Pages 527-533
    Published: July 15, 1986
    Released on J-STAGE: September 21, 2006
    JOURNAL FREE ACCESS
    We studied the fine structure and ultracytochemical features of microvessels of both normal rat cerebrum and brain tumors transplanted into rats. Ultrastructurally, the endothelial cells of the tumor vessels showed alterations, compared to those of normal vessels, such as attenuation, thickening, and/ or abnormal endothelial junctions. In the control rats, an ultracytochemical study revealed alkaline phosphatase (AlPase) and adenosine triphosphatase (ATPase) activities were located mainly on the luminal plasma membrane of the endothelial cells, and 5'-nucleotidase (5'-N) activity on the abluminal plasma membrane. In the transplanted brain tumors, the sites of AlPase and 5'-N activities were similar to those of the controls, but the extent of the reactions on the abluminal and luminal membranes of the endothelial cells was greater. ATPase activity occurred mainly on the luminal plasma membrane of the endothelial cells in the controls, and on the abluminal membrane in the transplanted brain tumors. The number of pinocytotic vesicles showing positive reactions for AlPase, 5'-N, and AT-Pase was not higher in the tumor vessels than in the normal vessels. The redistribution of membrane enzymes in the endothelial cells of the transplanted brain tumors is presumed to be related at least partly to the changes in the endothelial junction.
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  • Hajime TOHO, Kimiyoshi HIRAKAWA, Akihiko HINO, Jun KARASAWA, Yasuo OHN ...
    1986 Volume 26 Issue 7 Pages 534-540
    Published: July 15, 1986
    Released on J-STAGE: September 21, 2006
    JOURNAL FREE ACCESS
    Coagulation studies were performed in 11 patients in the acute stage of hypertensive intracerebral hemorrhage. The items tested include platelet count, prothrombin time, partial thromboplastin time, fibrinogen, antithrombin III, fibrin/fibrinogen degradation products, α2 macroglobulin, α2 plasmin inhibitor, fibrinopeptide A (FPA), and fibrinopeptide Bβ15-42 (FPBβ). Blood was collected from peripheral veins within 6 hours and again between the 7th and 14th days after the onset of symptoms. Disseminated intravascular coagulation (DIC) occurred in one patient, in whom the tests were repeated several times for 14 days.
    Fibrinopeptide levels were extremely high within 6 hours after the onset of symptoms and normalized between the 7th and 14th days. Fibrinopeptides were especially high in the patient with DIC, which was caused by primary brain damage. Normal FPA levels were restored sooner than those of the other substances after administration of heparin and gabexate mesilate.
    It appears that damage to cerebral tissue occasionally brings about DIC and that FPA and FPBβ may be excellent indices for predicting coagulation and fibrinolytic imbalance and for managing DIC.
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  • —Case Report—
    Hirofumi NAGANUMA, Shuji IMAI, Tetsuo WAKAO, Hidehito KOIZUMI, Jinichi ...
    1986 Volume 26 Issue 7 Pages 541-544
    Published: July 15, 1986
    Released on J-STAGE: September 21, 2006
    JOURNAL FREE ACCESS
    We encountered a male patient with a pneumocephalus secondary to acute sinusitis. A fistula between the sphenoid sinus and the intracranial cavity, probably the subarachnoid space, was detected during puncture and irrigation of the sphenoid sinus. This fistula might have been quite small and might have closed spontaneously. Sellar tomograms and metrizamide computed tomographic cisternography had failed to disclose the fistula.
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  • —Case Report—
    Masaharu SATO, Shigeru TANAKA, Akitsugu KOHAMA, Teruki SONE, Masao FUK ...
    1986 Volume 26 Issue 7 Pages 545-547
    Published: July 15, 1986
    Released on J-STAGE: September 21, 2006
    JOURNAL FREE ACCESS
    A 45-year-old male suffered from bilateral putaminal hemorrhages that occurred simultaneously, followed by pseudo-bulbar palsy. Administration of anticoagulants appeared to have caused the bleeding. Cerebral blood flow was markedly decreased in both hemispheres disproportionally to the small size of the hemorrhages, probably due to a bilateral “diaschisis phenomenon, ” and the patient experienced severe neurological sequelae.
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  • —Case Report—
    Katsuzo KIYA, Tamotsu KITAOKA, Masayuki NOMURA, Nobuyoshi SATO, Masash ...
    1986 Volume 26 Issue 7 Pages 548-551
    Published: July 15, 1986
    Released on J-STAGE: September 21, 2006
    JOURNAL FREE ACCESS
    A 17-year-old female presented with a small pontine hematoma considered as having arisen from rupture of a capillary telangiectasis. Vertebral angiography showed fenestration of the left distal vertebral artery without any vascular anomaly in the pons. Histological examination of the surgical specimen verified the presence of a capillary telangiectasis adjacent to the hematoma. Rupture of a capillary telangiectasis as the source of pontine hematoma is very rarely documented histologically in surviving patients.
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  • —Case Report—
    Yutaka SHIMAMURA, Yasuto KAWAKAMI, Takashi TAMIYA, Takuya CHIHARA
    1986 Volume 26 Issue 7 Pages 552-555
    Published: July 15, 1986
    Released on J-STAGE: September 21, 2006
    JOURNAL FREE ACCESS
    The authors encountered a patient with an anomalous external carotid-vertebral anastomosis, which was found incidentally during examination for a recurrent pituitary adenoma. Left carotid angiography demonstrated a muscular branch of the ascending pharyngeal artery feeding the left vertebral artery, while bilateral retrograde vertebral angiography failed to demonstrate the origins of either vertebral artery. To our knowledge, this is the first documented case of ascending pharyngealvertebral anastomosis associated with the bilateral absence of vertebral arteries at their origins.
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  • —Case Report—
    Shigeo INOMORI, Ilu KIM, Shinsuke UEDA, Shinsa PAK
    1986 Volume 26 Issue 7 Pages 556-559
    Published: July 15, 1986
    Released on J-STAGE: September 21, 2006
    JOURNAL FREE ACCESS
    We treated a male patient with a solitary osteochondroma of the cervical spine that caused spinal cord compression. Computerized tomography demonstrated a mass arising from the C4-5 vertebrae, projecting into the spinal canal, and compressing the spinal cord. Decompressive laminectomy was performed initially, followed 1 month later by total removal of the tumor through an anterior transcervical approach. Our case and other reported cases of solitary osteochondroma of the vertebral column are discussed.
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  • —Case Report—
    Jamshid JAMSHIDI, Kentaro KOSHINO, Heitaro MOGAMI
    1986 Volume 26 Issue 7 Pages 560-563
    Published: July 15, 1986
    Released on J-STAGE: September 21, 2006
    JOURNAL FREE ACCESS
    Only four cases of intracranial lipoma confined to the sylvian fissure have so far been reported. In this paper we describe an intracerebral lipoma that apparently arose from the connective tissue of the sylvian fissure in a 31-year-old male. To our knowledge, no other case of this kind has been reported. We successfully excised the entire tumor, using microsurgical techniques. The patient developed a minor motor deficit postoperatively, but eventually fully recovered.
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  • —Case Report—
    Shunji NISHIO, Masashi FUKUI, Toru IWAKI, Takato MORIOKA, Katsutoshi K ...
    1986 Volume 26 Issue 7 Pages 564-570
    Published: July 15, 1986
    Released on J-STAGE: September 21, 2006
    JOURNAL FREE ACCESS
    In an autopsy of a 16-year-old female with a primary intracranial yolk sac tumor (endodermal sinus tumor), histological evaluation of the surgical specimen obtained from the pineal region showed proliferation of undifferentiated neoplastic embryonal cells without characteristic histological features, such as periodic acid-Schiff-positive hyaline droplets or Schiller-Duval bodies. Ultrastructural study of the tumor cells, however, revealed typical cytological features of yolk sac tumor, including a voluminous, homogeneous, basement membrane-like substance, both within and outside of the cells, and intracytoplasmic vesicles containing amorphous material. Alpha-fetoprotein was detected in serum and cerebrospinal fluid by radioimmunoassay and within tumor tissues by immunohistochemical techniques. After surgery, chemotherapy with cis-diamminedichloroplatinum (II), vinblastine, and bleomycin was employed without significant benefit, and the patient died 5 months after tumor removal. Histological examination of the tumor at autopsy supported the diagnosis of yolk sac tumor. Electron microscopic and immunohistochemical studies of germ cell tumors are discussed.
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  • —Case Report—
    Isao DATE, Yasunori YAGYU, Takuji BUKEO
    1986 Volume 26 Issue 7 Pages 571-574
    Published: July 15, 1986
    Released on J-STAGE: September 21, 2006
    JOURNAL FREE ACCESS
    In a 57-year-old female patient, a solitary skull metastasis of endometrial stromal sarcoma of the uterus was found under the left parietal region of the cranium 1 year after total removal of the primary lesion. The histological features of the skull mass were similar to those of the original tumor. Fifteen months after excision of the skull metastasis the patient remains asymptomatic. This is the first such case reported.
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  • —Report of Two Cases—
    Taizo NITTA, Sumio KUDOH, Kazufumi ITOH, Shozo ISHII
    1986 Volume 26 Issue 7 Pages 575-578
    Published: July 15, 1986
    Released on J-STAGE: September 21, 2006
    JOURNAL FREE ACCESS
    Two cases of huge subependymoma of the lateral ventricle are described. Computed tomographic scans showed that the tumors occupied the entire intraventricular space; however, both were easily removed via the transcortical approach. Histological examination revealed that one tumor was a pure subependymoma and the other was a mixture of subependymoma and cellular ependymoma. The cytogenesis of subependymoma, with emphasis on the subependymal cell plate, is discussed.
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