Neurologia medico-chirurgica
Online ISSN : 1349-8029
Print ISSN : 0470-8105
ISSN-L : 0470-8105
Volume 34, Issue 7
Displaying 1-10 of 10 articles from this issue
  • Naoyuki NAKAO, Toru ITAKURA, Yuji UEMATSU, Mitsukazu NAKAI, Norihiko K ...
    1994 Volume 34 Issue 7 Pages 407-411
    Published: 1994
    Released on J-STAGE: May 22, 2006
    JOURNAL FREE ACCESS
    The effects of pretreatment with interleukin-1 (IL-1) on neurite growth and cell survival of rat superior cervical ganglion (SCG) explants were examined. Neonate rat SCG explants were cultured with serumcontaining growth media. Pretreatment with IL-1β (30 U/ml) for 3 hours stimulated neurite outgrowth of the SCG explant, which was inhibited by the addition of anti-nerve growth factor (NGF) antibody to the growth medium. Adult rat autologous SCG with the same pretreatment and nontreated ganglia were transplanted into the lateral ventricle. Histological evaluation of the grafts 2 weeks after transplantation revealed that the pretreated SCG cells survived better. Pretreatment with IL-1 may achieve the NGF-mediated neurotrophic effect in sympathetic ganglionic neurons resulting in enhanced graft survival.
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  • Shinji NAGAHIRO, Satoshi GOTO, Kasei KOGO, Minako SUMI, Mutsumasa TAKA ...
    1994 Volume 34 Issue 7 Pages 412-417
    Published: 1994
    Released on J-STAGE: May 22, 2006
    JOURNAL FREE ACCESS
    Sequential and regional changes in ischemic edema following various durations of focal cerebral ischemia were studied by magnetic resonance (MR) imaging in a rat unilateral intraluminal middle cerebral artery occlusion model. Occlusion was performed from 5 minutes to 5 hours. T2-weighted images were obtained chronologically 6 hours after onset of ischemia, on day 1 and day 7. An immunohistochemical study using antibodies to calcineurin and glial fibrillary acidic protein was performed to observe histological changes in the ischemic brain. The T2 high-signal-intensity areas representing ischemic edema were observed in the lateral striatum and/or the cerebral cortex by day 1 in all rats with 1- to 5-hour ischemia, and the areas were larger and detected earlier with longer durations of ischemia. In three of six rats with 15-minute ischemia and five of six rats with 30-minute ischemia, the T2 high-signal-intensity areas appeared transiently on day 1 in the dorsolateral striatum where loss of neurons expressing calcineurin immunoreactivity and associated gliosis were found. MR imaging in animal models of reversible focal ischemia can achieve sequential and noninvasive evaluation of dynamic regional changes in ischemic edema.
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  • Hiroyuki NAKASE, Takaoki TADA, Hiroshi HASHIMOTO, Shinichiro KUROKAWA, ...
    1994 Volume 34 Issue 7 Pages 418-422
    Published: 1994
    Released on J-STAGE: May 22, 2006
    JOURNAL FREE ACCESS
    L-glutamate (Glu) and L-aspartate (Asp) are two major excitatory amino acids that may be involved in seizure susceptibility and seizure induction. The concentrations of Glu and Asp were measured by microdialysis in the epileptic focus in a cat amygdaloid kindling model. Sequential changes in Glu and Asp (before, during, and after seizure) were measured in the partial seizure (S4) and generalized seizure (S6) groups. By stimulation at and 50μA below the partial seizure-triggering threshold in the S4 group and the generalized seizure-triggering threshold in the S6 group, Glu was released from the epileptic focus in the S4 group, and both Glu and Asp were released in the S6 group after seizure and stimulation (below threshold), and the amount of Glu and/r Asp release determined seizure induction. Excitatory amino acids may be the trigger of seizure induction in the cat amygdaloid kindling model.
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  • Slobodan MARINKOVIC, Hirohiko GIBO, Atila ERDEM
    1994 Volume 34 Issue 7 Pages 423-428
    Published: 1994
    Released on J-STAGE: May 22, 2006
    JOURNAL FREE ACCESS
    A huge uncal branch of the anterior choroidal artery was found in one of 22 cerebral hemispheres. The uncal artery measured 0.7 mm in diameter. It gave off small branches to the uncus, as well as a large parahippocampal artery, the accessory anterior temporal artery, and the anterior hippocampal artery. This uncal artery supplied, in addition to the uncus, most of the ventromedial surface of the parahippocampal gyrus, part of its dorsal surface, the rostromedial portion of the lateral occipitotemporal gyrus, and the rostral part of the hippocampal formation. Such a huge uncal artery has implications for surgery in the uncohippocampal region.
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  • Satoshi NAKASU, Ken-ichi MATSUMURA, Hirofumi NIOKA, Jyoji HANDA
    1994 Volume 34 Issue 7 Pages 429-435
    Published: 1994
    Released on J-STAGE: May 22, 2006
    JOURNAL FREE ACCESS
    The maturation process of basal cells in craniopharyngiomas was studied using a panel of lectins, and antibodies against cytokeratin 13 and bcl-2 protein, using oral mucosa for comparison. Seven lectins were employed: peanut (Arachis hypogaea) agglutinin, Dolichos biflorus agglutinin (DBA), Ulex europaeus agglutinin-I (UEA-I), soybean agglutinin, Ricinus communis agglutinin-I, succinyl wheat germ agglutinin, and Pisum sativum agglutinin. DBA and cytokeratin 13 stainings of the suprabasal cells in craniopharyngiomas were comparable to those of the oral mucosa, but not to those of the skin. Staining patterns of the basal cells in the oral mucosa and craniopharyngiomas were generally similar, but UEA-I binding and bcl-2 protein expression in suprabasal cells differed. The difference appeared to be due to a disturbance in the differentiation of the basal cells, because only a small fraction of the basal cells followed a normal maturation process in craniopharyngiomas in comparison to the oral mucosa. The expression of bcl-2 protein may be involved in the pathogenesis of craniopharyngiomas.
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  • Mikihiko TAKESHITA, Osami KUBO, Hirofumi HIYAMA, Yasuhiko TAJIKA, Masa ...
    1994 Volume 34 Issue 7 Pages 436-439
    Published: 1994
    Released on J-STAGE: May 22, 2006
    JOURNAL FREE ACCESS
    The intracapsular cholesterol, protein, and calcium contents of epidermoid and dermoid cysts from seven patients were compared with the signal intensities on T1-weighted spin-echo magnetic resonance (MR) images. All specimens had a paste-like consistency when resected. Epidermoid and dermoid cysts demonstrated a wide range of cholesterol and calcium contents, and epidermoid cysts were not always rich in cholesterol. Five patients had cysts with lower signal intensity than white matter, which contained more than 18.3 mg/g wet weight of protein. One of these patients had the highest cholesterol content of all seven patients (22.25 mg/g wet weight) and another had the highest calcium content (0.75 mg/g wet weight). Two patients had cysts with higher signal intensity than white matter, with protein contents of lower than 4.3 mg/g wet weight. High protein content (> 18.3 mg/g wet weight) may decrease signal intensity on T1-weighted MR images, while low protein content (<4.3 mg/g wet weight) may increase signal intensity in epidermoid and dermoid cysts with high viscosity (paste-like consistency) contents.
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  • Tsuyoshi SHIMOMURA, Shigeaki HORI, Naoto KASAI, Kenichi TSURUTA, Hitos ...
    1994 Volume 34 Issue 7 Pages 440-443
    Published: 1994
    Released on J-STAGE: May 22, 2006
    JOURNAL FREE ACCESS
    A rare case of meningioma associated with intratumoral abscess formation occurred in a 64-year-old female presenting with septic meningitis and a right frontal mass lesion after a gynecological operation under spinal anesthesia. The mass lesion was totally removed and revealed as an incidental meningioma with an intratumoral abscess. Hematogenous infection of Bacteroides oralis was thought to be the cause of the intratumoral abscess formation.
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  • Satoshi HIROSE, Sadahiro SHIMADA, Ryuhei KITAI, Hirokazu KAWANO, Toshi ...
    1994 Volume 34 Issue 7 Pages 444-447
    Published: 1994
    Released on J-STAGE: May 22, 2006
    JOURNAL FREE ACCESS
    A 5-year-old boy presented with diploic epidermoid tumor associated with subperiosteal hematoma caused by minor trauma. The tumor was removed completely together with the hemorrhage. Bleeding from this type of tumor is unusual, but should be considered as an indication for surgical removal.
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  • Akira WATANABE, Mitsuro YANAGITA, Ryoji ISHII, Teruo SHIRABE
    1994 Volume 34 Issue 7 Pages 448-450
    Published: 1994
    Released on J-STAGE: May 22, 2006
    JOURNAL FREE ACCESS
    A rare case of ecchordosis physaliphora clearly demonstrated by magnetic resonance (MR) imaging is described in a 48-year-old male who presented with right hearing disturbance and reduction in sensation in the right side of his face due to a large cystic schwannoma. MR imaging revealed the large cystic schwannoma as well as an abnormal clival lesion. The clival lesion was hypointense on T1-weighted images and hyperintense on T2-weighted images, and not enhanced by gadolinium-diethylenetriamine-penta-acetic acid (Gd-DTPA) administration. The clival lesion was partially removed. The histological diagnosis was ecchordosis physaliphora. The postoperative course was uneventful. The absence of enhancement of ecchordosis physaliphora by Gd-DTPA administration may be a characteristic finding, in contrast to chordoma which is generally enhanced.
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  • Hiroyasu YAMAKAWA, Katsunobu TAKENAKA, Yasuhiko SUMI, Toshihiro MORITA ...
    1994 Volume 34 Issue 7 Pages 451-454
    Published: 1994
    Released on J-STAGE: May 22, 2006
    JOURNAL FREE ACCESS
    A 69-year-old male with an intracranial bullet retained in the right occipital lobe for 45 years presented with epileptic seizure occasionally accompanied by visual hallucinations. Neurological examination revealed left homonymous hemianopsia and right hearing loss, and electroencephalography showed slow discharges localized in the lesion. The bullet was removed together with the thickened fibrous capsule. His postoperative course was uneventful, and he has become seizure-free. The bullet caused metal toxicity and progressive gliosis, which caused the epileptogenetic focus and associated hallucinations.
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