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Volume 49, Issue 2
Displaying 1-5 of 5 articles from this issue
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Ramachandran SUMATHI, Govindasamy BASKARAN, Palaninathan VARALAKSHMI1996 Volume 49 Issue 2 Pages 39-48
Published: 1996
Released on J-STAGE: March 19, 2010
JOURNAL FREE ACCESSCadmium, a divalent metal toxicant, preferentially localizes in hepatocytes and causes liver injury. DL α-lipoic acid is a dithiol which is effective in rendering protection against cadmium - associated liver damage, by virtue of its two sulfhydryl moieties. Lipoate was administered to cadmium-exposed rats which were either prior administered with buthionine sulfoximine to deplete liver glutathione or not. During lipoate treatment, significant protection was rendered against cadmium toxicity even under glutathione-depleted experimental condition. This highlights the antioxidant property of lipoic acid and its efficacy in mitigating cadmium - associated liver assault even in the absence of glutathione synthesis.View full abstractDownload PDF (810K) -
Rathnavel SIVAPRAKASH, Usha Anand RAO, Sadras Panchatcharam THYAGARAJA ...1996 Volume 49 Issue 2 Pages 49-56
Published: 1996
Released on J-STAGE: March 19, 2010
JOURNAL FREE ACCESSThe most common type of gastric carcinoma, namely the intestinal type, has been proposed to result from a precancerous process in which chronic gastritis, atrophy, intestinal metaplasia and dysplasia develop in a sequential manner. Helicobacter pylori is considered as the main cause of chronic atrophic gastritis and thus may play a role in the gastric carcinogenesis process. The present study was aimed at investigating the prevalence of H. pylori in the gastric carcinoma cases. Urease tests and ELISA developed in our laboratory and culture were used to assess the prevalence of H. pylori in the study group. The positivity of H. pylori by various tests ranged from 56.0 to 62.6% in the gastric carcinoma group and 37.3 to 46.6% in the control subjects, the difference being statistically significant. This suggests that H. pylori infection could be associated with an increased risk for gastric carcinoma, but only a very small percentage of the infected persons develops gastric carcinoma. Therefore, it is suggested that along with other critical risk factors, H. pylori may act as a cofactor in the pathogenesis of gastric carcinoma.View full abstractDownload PDF (1929K) -
Kaushal KUMAR, Rakesh KATYAL, Kuldip Singh GILL, Syed JAMIL-UR-RAHMAN1996 Volume 49 Issue 2 Pages 57-62
Published: 1996
Released on J-STAGE: March 19, 2010
JOURNAL FREE ACCESSA rapid survey in Delhi and surrounding areas was undertaken in September 1994, during plague outbreak in District Beed (Maharashtra) and Surat (Gujarat) to monitor rodent/flea population and to determine susceptibility status of fleas to insecticides. The five rodent species in order of their prevalence were Rattus rattus (86.06%), Mus musculus (15.33%), Suncus murinus (2.47%), Bandicoota indica (0.48%) and B. bengalensis (0.48%) . Two flea species, Xenopsylla cheopis and X. astia, were captured from these rodents. The absolute flea index was found to be ranging between 0.08 to 4.0 in various localities. X. cheopis and X. astia indexes were ranging between 0.22 to 2.08 and 0.08 to 4.0, respectively.
Susceptibility test results with X. cheopis collected and reared in the laboratory revealed that it is resistant to DDT and Dieldrin, tolerant to Malathion and susceptible to K-othrin (Deltamethrin) .View full abstractDownload PDF (441K) -
Tamaki OKABAYASHI, Nozomi MIURA, Singo MIYAZAKI, Tomomi NIGO, Yasukazu ...1996 Volume 49 Issue 2 Pages 63-68
Published: 1996
Released on J-STAGE: March 19, 2010
JOURNAL FREE ACCESSThe prevalence of antibody against spotted fever group rickettsia (SFGR) was investigated with Rickettsia japonica antigen in small rodents captured in an area in Hokkaido, where no human cases of SFGR infection had been reported. Antibody against SFGR was found in Apodemus speciosus and Clethrionomys rufocanus but not in Apodemus argenteus. None of these rodents had antibody against R. typhi. This is the first report of the antibody against SFGR in rodents in Hokkaido.View full abstractDownload PDF (441K) -
Ima-Nurisa IBRAHIM, Mohammad SUDOMO, Chiharu MORITA, Sachiko UEMURA, Y ...1996 Volume 49 Issue 2 Pages 69-74
Published: 1996
Released on J-STAGE: March 19, 2010
JOURNAL FREE ACCESSThe prevalence of antibodies against Seoul virus was investigated in 655 wild rats (Rattus norvegicus, R. rattus, R. rattus diardii, R. exulans, R. tiomanicus) captured in seven port areas of Indonesia. Twenty-four of 238 R. norvegicus, one of 142 R. rattus and one of 102 R. exulans from two port areas had the antibodies against Seoul virus.View full abstractDownload PDF (418K)
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