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Volume 43, Issue 4
Displaying 1-23 of 23 articles from this issue
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Availability of Intraoperative Brushing Cytology and Aspilation Cytology for Lateral MarginT. Adachi1990 Volume 43 Issue 4 Pages 517-525
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSThe distance from the outermost part of rectal cancer to the resected margin (ew) is a important factor for its local recurrence. Practically, in the investigation of 65 rectal cancer patients who underwent resection of rectum, a group of less than 3 mm in ew showed a significantly higher recurrence rate than these in other groups. In order to detect residual cancer cells at the laterally resected margin and to diagnose “ew” during operation, we carried out brushing and aspiration cytology for the resected margin.
The intraoperative brushing cytology in 41 cases reuealed the sensitivity of 75 %, the specificity of 100 % and the accuracy of 95 %. And, the results of the intraoperative aspiration cytology in 300 aspirations indicated the sensitivity of 90 %, the specificity of 94 % and the accuracy of 91 %.
So we conclude that brushing and aspiration cytology are rapid, easy, and accurate methods to diagnose lateral residual cancer cells and “ew”.View full abstractDownload PDF (1713K) -
Yoriyuki Tsuji1990 Volume 43 Issue 4 Pages 526-532
Published: 1990
Released on J-STAGE: February 05, 2010
JOURNAL FREE ACCESSExaminations by means of transanal ultrasonography were performed on 28 cases of anal fistula and 22 perianal abscess who were operated afterwards in our hospital, and the following results were obtained ;
1) Internal and external sphincter muscles of the anus were identified and the dentate line was also identified by injecting local anesthetic solution at the line.
2) The examinations made it possible for us to make preoperative diagnoses of II L, II H, III and IV respectively on Sumikoshi classification,
3) It was found that most of ischiorectal fistula (III) were accompanied with intermuscular lesion (II) and II H was predominant.
4) There were many cases of pelvirectal fistula (IV) which were formed by expansion of ischiorectal fossa lesion (III) breaking through levator ani muscle. There were, however, some exceptance cases in Crohn's disease et al.View full abstractDownload PDF (1205K) -
A IIDA1990 Volume 43 Issue 4 Pages 533-541
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSHistopathological types and survival were studied in 408 colo-rectal cancer patients. The specimens were devided into well, moderately, or poorly, differentiated adenocarcinoma and others. The rate of lymphatic metastasis and the depth of the infiltration through the rectal wall was more prominent in moderately differentiated adenocarcinoma. In patients with moderately differentiated adenocarcinoma had poorer survival rate, and shorter survival time than patients with well differentiated adenocarcinoma having the same background facters.View full abstractDownload PDF (1786K) -
K Maeda1990 Volume 43 Issue 4 Pages 542-553
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSIt is often technically difficult to anastomose the colon near the peritoneal reflection with apprehension regarding severe ischemia in the distal colon after extended left-sided hemicolectomy. This study was designed to investigate how far proximally from the peritoneal reflection the middle and inferior rectal arteries can nourish the distal colon after the high ligation of the infererior mesenteric artery on extended left-sided hemicolectomy.
Viability of the ischemic colon and the critical level of ischemia for safe colonic anastomosis were studied experimentally with both fluorescence pattern and tissue partial oxygen tension (PtO2) five minutes after producing ischemia. The ischemic colon with no fluorescence pattern (PtO2 16 mmHg) was not viable. Ischemic colons showing normal (PtO2 52 mmHg), fine patchy (PtO2 41 mmHg), or coarse patchy pattern (PtO2 27 mmHg) showed satisfactory anastomosic healing.
Observations in nine patients undergoing extended left-sided hemicolectomy revealed sufficient blood flow for anastomosis in the distal colon up to 20 cm from the peritoneal reflection and even higher in some case.View full abstractDownload PDF (2129K) -
N Ishijima1990 Volume 43 Issue 4 Pages 554-560
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSThe expression of ras oncogene p21 was determined immunohistochemically, using an avidin-biotin peroxidase method with anti ras p21 rat monoclonal antibody (Y 13-259), in 72 carcinomas, 30 adenomas and 75 normal mucosae of the colorectum.
Intense immunoreactivity for ras oncogene p21 was detected in 39 (54 %) carcinomas, in 24 (80 %) adenomas and in 7 (9 %) normal mucosae. The increased expression of ras oncogene p21 was found in the luminal surface of normal colonic mucosa. The increased expression of ras oncogene p21 was significantly higher in colorectal neoplasia than in normal mucosa and it was significantly higher in adenomas than in carcinomas. There was no correlation between the increased expression of ras oncogene p21 and the advanced stage of carcinomas. These results suggested that ras oncogene protein (p21) may play a role in the evolusion and transformation of colorectal neoplasia, as well as in the differentiation of normal colonic epithelium, but play no significant role in the progression of overt colorectal carcinomas.View full abstractDownload PDF (1269K) -
M Takano1990 Volume 43 Issue 4 Pages 561-571
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSRecently, sphincter-preserving operations are all the more applied for the radical treatment of various forms of anal fistulas. However, few papers are written on the long-term results. Here are analysed the recurrence cases among 362 cases which were treated in our clinic with sphincter-preserving methods. The recurrence cases are 16 cases (6.6%) and the recurrence rates of each type of the fistulas are ; 1.5 % in low intersphincteric fistula (II L), 3.6 % in high intersphincteric fisutla (II H), 9.5 % in ischiorectal fistula (III) and 23.8% in pelvirectal fistula (IV) respectively. The average days required for the complete healing of operational wounds are ; 27 in II L, 33.3 in II H, 51.2 in III and 55.3 in IV. The reasons and the frequencies for the recurrence are ; remaining of primary opening in 2, remaining of primary abscess in 5 and insufficient and/or improper resection of fistulous tracts in 8 cases.View full abstractDownload PDF (1703K) -
M Okuno, T Ikehara, M Nagayama, T Nishimori, K Togo, M Kawaguchi, H Ya ...1990 Volume 43 Issue 4 Pages 572-576
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSClinicopathological study was performed, based on 73 cases with 79 early colorectal carcinomas-intramucosal (m); 37 and submucosal (sm); 42-which had been treated in a period of 16 years from 1973 to 1988 at our surgical department. As the definitive treatment for these lesions, endoscopic polypectomy was performed in 14 lesions (13 cases), local excision in 5 lesions (5 cases) and colectomy or proctectomy with lymph node dissection in 60 lesions (57 cases). These early carcinomas accounted for 8.5 per cent of all colorectal carcinomas treated during the same period. However, the frequency of early carcinoma had increased up to 15.0 per cent for the last 4 years. Gross configuration of these lesions was classified into 4 types ; I p (pedunculated) type in 29 lesions, I s (sessile) type in 22 lesions, II a (flat elevated) type in 20 lesions and II a+ II c (flat elevated with depression) type in 8 lesions. It was interesting to note that 7 out of 8 lesions classifild as II a+ II c type were sm-carcinoma.
Lymph node involvement was observed in 5 out of 37 sm-carcinomas. The lesions which showed II a or II a+ II c type in gross configuration, or revealed to be moderate or poorly differentiated adenocarcinoma, or had positive lymphatic vessel invasion, tended to have positive lymph node involvement.
We had experienced two cases with local recurrence after the treatment for m-and sm-carcinomas, and thereafter reoperations could be performed curatively. In other cases no recurrence had been observed during the follow-up period.View full abstractDownload PDF (1024K) -
J Songjie, Y Saito, T Muto, T Masaki, Y Morioka1990 Volume 43 Issue 4 Pages 577-582
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSWe examined the influence of high fat diet on the carcinogenesis of the colon cancer induced by DMH in the 2 groups of experiments as follows.
Group I -DMH 20 mg/kg x 1+MF diet (n=12)
DMH 20 mg/kg x 1+Wilgram diet (n=12)
Group II -DMH 20 mg/kg/week x 3+MF diet (n=12)
DMH 20 mg/kg/week x 3 +Wilgram diet (n= 12)
Male Spraque-Dawley rats were used in the both groups. The rats were sacrificed after 28 weeks and the grossly recognized tumors together with the flat background mucosa were histologically studied, particularly by serial sections for the latter.
It is interesting to note that atypical glands developped by injecting low dose of DMH although only a few grossly visible tumors were induced. The high fat diet (Wilgram) had no significant effect on the grossly recognized tumor, however, it had promoting effect on the development of atypical glands in the flat background mucosa. In addition, the grade of atypic was higher in the high fat group as compared with the control group (MF). It is concluded that the high fat diet has promoting effect on the development of atypical glands in the flat mucosa which could be a precursor of the grossly visible tumor in the experimental colon cancer model by DMH.View full abstractDownload PDF (998K) -
Y Sakurai, A Aoki, S Okazeri, R Nakayama1990 Volume 43 Issue 4 Pages 583-589
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSIn a series of 327 colorectal cancer patients surgically treated in Hiratsuka City Hospital during 1970-1989, 179 patients without regional lymph node metastasis and without distant metastasis (n (-) group) were selected to compare the clinicopathologic findings and the prognosis with those in 105 patients with regional lymph node metastasis and without distant metastasis (n (+) group). The mean age of the n (-) group was significantly higher than that of the n (+) group (P<0.05) and the proportion of male patients in the n (-) group was also significantly higher than that in the n (+) group (P<0.05). Proportion of the cases without lymphatic vessel invasion in the n (-) group was 64.0 % and was significantly higher than that in the n (+) group (P<0.01). However, the number of patients without venous invasion was not significantly different between the two group. There was no difference in cumulative survival rate of patients in the n (-) group in respect to the back ground factors such as sex, tumor site, histological type, and venous invasion. However, survival rate of patients whose cancer invasion was limited within the mucosa, submucosa and proper muscle was significantly better than that of patients whose cancer extended from the mucosa beyond the proper muscle (P<0.01). Survival rate in patients with and without lymphatic vessel invasion was not significantly different (P<0.05). Among patients in the n (-) group, 11 patients eventually died of recurrence. The tumor site in 9 patients was the lower rectum and the depth of invasion in these patients was beyond the proper muscle. The mean survival was 35 months. Eight patients developed distant metastasis such as lung, liver and bone. These data indicated that rectal cancers which appeared especially in the lower rectum and extended beyond the proper muscle had a high risk of recurrence among colorectal cancer patients without lymph node involvement.View full abstractDownload PDF (1111K) -
S Kameoka, H Shindo, K Asahina, K Nakajima, K Miyazaki, H Kanzaki, M I ...1990 Volume 43 Issue 4 Pages 590-594
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSThe presence of positive lymph nodes along the inferior mesenteric artery (IMA) in patients with cancer of the sigmid colon and rectum has a significant impact on the treatment modality. We have tried to detect lymph nodes metastasis in this region ultrasonographically using 7.5 MHZ probe, in patients with cancer of the Sigmoid colon and rectum preoperatively. Since January of 1988, 100 screening patients and 55 patients with cancer of the sigmoid colon and rectum have been studied.
In the 100 cases of screening patients, IMA were depicted in 88 %, and not depicted in 12 %. The reasons for IMA nonvisualized ultrasonically were obesity, and not age and sexuality. The distances of the IMA visualized ultrasonically were as follows : shorter than 20 mm ; in 9 cases, 21-19mm ; in 38 cases, and longer than 40 mm ; in 41 cases.
In the 55 cases of rectosigmoid cancer, we detected IMA ultrasonically in 85.5 % of the total cases and we made the diagnosis swelling of the lymph nodes in 15 cases, of whom 9 cases were histopathologically metastatic lymph nodes : sensitivity 100 %, specificity 84.2 %, positive predictive value 60 %, and negative predictive value 100 %.View full abstractDownload PDF (4863K) -
(The Effect of Mitomycin Administrated into the Portal Vein)S Yasuda, T Noto, M Ikeda, M Mukai, H Nakazaki, T Tajima, T Mitomi1990 Volume 43 Issue 4 Pages 595-600
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSA mouse model has been developed for studying the treatment of colorectal liver metastasis. Single cell suspensions were obtained from transplantable mouse colon cancer (colon 26, BALB/c). Tumor cells (103, 104, 105) were inoculated into the portal vein of syngenic mice. On the day 8 after inoculation, all mice showed microscopic liver metastasis. No macroscopic metastsis was observed. On the day 18 after inoculation of 105 cells, all mice showed macroscopic liver metastasis. This tumor also proved to be sensitive to mitomycin (MMC). This model seemed to be useful for studying the treatment of colorectal liver metastsis.
This model was applied to experimental chemotherapy. We investigated the inhibitory effect of intraportal MMC administration on the growth of hepatic micrometastasis. On the day 8 after 105 tumor cells inoculation, one group of mouse were relaparotomized and MMC (70μg/body) was administered into the portal vein (treated group). Another group of mouse were observed without treatment (control group). When mice were killed 18 days after inoculation, the average number of metastatic nodules was smaller, and the mean liver weight was lower in the treated group. In addition, significant prolongation of survival days was achieved in the treated group. These results indicated that intraportal administration of sensitive drugs might inhibit the growth of micrometastasis of the liver.View full abstractDownload PDF (2954K) -
A. Yamaguchi, T. Ii, S. Takegawa, T. Ishida, G. Nishimura, M. Katho, M ...1990 Volume 43 Issue 4 Pages 601-605
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSWe studied 35 patients who had resection of hepatic metastases from colorectal cancer.The overall three-year and five-year survival rates were 53 % and 35 %, respectively. The survival of patients with metachronous metastases (45.8 /o alive at 5 years) was slightly better than of that patients with synchronous metastases (28.3 /o alive at 5 years). No significant relationship between metastatic tumor characteristics (number of metastases, lobar distribution of metastases and size of largest lesion) and prognosis was found. Also stage of primary resected lesion and surgical methods were not related to prognosis of patients. Survival of patients with DNA diploid metastases (71 % alive at 5 years) was significantly better than that of patients with DNA aneuploid metastses (34.1 % alive at 3 years and 17.0 % alive at 5 years) (p<0.05). In a Cox multivariate regression analysis, DNA ploidy pattern was most powerful prognostic indicator in resected hepatic metastases. These results demonstrated that flow cytometric DNA ploidy measurements may have prognostic value for patients with resected hepatic metastases from colorectal cancer.View full abstractDownload PDF (722K) -
CJ Park, KC Lee, Y Sumikoshi1990 Volume 43 Issue 4 Pages 606-612
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSPathophysiology in fuctionnal defeation disorders was not well understood till recently.
Fecal passage from the rectum through the anal canal may be well visualized by technique of defecography.
This is a report based on 95 defecographs from 73 patients with defecation disorders and 22 healthy volunteers as a control group.
We have obsained the following results ;
1. Rectocele was found in 33 cases, rectal intussusception in 14 cases, spastic levator syndrome in 5 cases, perineal descent in 43 cases and rectal prolapse in 2 cases. No abnormalities were found in 14 cases.
2. In the control group, the anorectal angle (ARA) at rest (ARA1) was 96.1±9.5°, ARA during squeezing (ARA2) was 87.4±8.8° and ARA during straining (ARA3) was 118.0±13.6°.
3. The increment of ARA during straining (ARA3-ARA1) was significantly reduced in patients with rectocele and spastic levator syndrome.View full abstractDownload PDF (11119K) -
M Saitoh, N Kanoh, E Matsunami, E Wada1990 Volume 43 Issue 4 Pages 613-620
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSThis paper presents a case of Ileocecal actinomycosis. A 55-year-old woman presented with a complaint of left lower abdominal pain. Laparotomy under the preoperative diagnosis of ileocecal tumor revealed a mass existing from the lateral Ileocecal region to the anetrior abdominal wall. It formed a mass adhering to the transverse colon and great omentum. Right hemicolectomy was performed. The tumor measured 70×60 mm. The diagnosis of actinomycosis was established by histopathological evaluation of sulfar granule. Massive dose of penicillin was prescribed postoperatively. Thirty-seven cases of this disease reported in Japan were reviewed. None of them were correctly diagnosed preoperatively. The diagnosis was obtained in all the cases by postoperative evaluation of sulfar granule. Image diagnoses disclosed no characteristic features and showed the lesion only as a submucosal tumor-like change. Surgical resection of the lesion and long-term administration of antibiotics such as penicillin seemed necessary for the managment. This is recently a rare disease but it seems necessary to always bear in mind the possibility of encountering this disease in patients with ileocecal diseases.View full abstractDownload PDF (5609K) -
H Takeda, T Takahashi, S Ajitsu, H Togashi, M Ishikawa1990 Volume 43 Issue 4 Pages 621-625
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSA case of 81-year-old Japanese male with Ileocecal intussusception due to an ileal lipoma which revealed a tumorstain-like appearance in angiography is reported. The patient complained o abdominal fullness for 3 months. Barium enema and colonoscopy revealed an egg-sized tumor in the ascending colon. The tumor seemed to be continued with terminal ileal mucosa and prolapsed into the ascending colon. The tumor showed a round low density area approximately 3 cm in diameter by computed tomography and it also showed a hyperechoic shadow by ultrasonographic examination. Ultrasonography also revealed a multiple concentric ring sign adjacent to the tumor in the right lower abdominal scanning. From the above results, the tumor was first diagnosed a lipoma with intussusception. However, angiography revealed a tumorstain-like appearance in the venous phase. Because of these findings, we could not deny a malignant tumor, considering the case for the operative indication. The operative specimen revealed a benign lipoma (4.5×3.0×3.0cm) located in the ileum, 10 cm proximal to the ileocecal valve. As for the tumorstain-like appearance we speculated that it was derived from the difference of angiographic staining between ileum and colon, as well as due to an inflammatory change of the surface mucosa.View full abstractDownload PDF (7558K) -
S Nabeshima, Y Ooeda, N Yamamoto, M Suzuki, S Murakami1990 Volume 43 Issue 4 Pages 626-630
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSA 15-year-old boy was admitted to our hospital presenting with consistent abdominal pain and intestinal obstruction. He was diagnosed as having descending colon carcinoma and operated after decompression with long intestinal tube. Spreadings of cancer to the whole abdominal cavity was remarkable, and adjacent organs were involved locally. The tumor could not be resected. Histological diagnosis was mucin-producing adenocarcinoma and the patient died 5 months later.
According to the analysis of 49 cases on primary carcinoma of the colon in children under 15 years of age, reported in Japanese literatures including this case, it showed that adolescent boys and the cases of cancer in transverse colon have poor risk factors and most of the cases who had these factors are stage IV-V. Patients who visited to hospital because of bloody stool and were diagnosed colon cancer preoperatively showed relatively long term survival. Patients of signet-ring cell carcinoma showed poor prognosis. However there is no difference on prognosis between mucinous carcinoma and adenocarcinoma, contrary to the preceding publications.
This analysis indicates that early diagnosis and adequate surgical removal could improve the prognosis of the disease in children.View full abstractDownload PDF (2892K) -
T Sekioka, O Nakai, O Iizuka, K Endou, M Omatsu, T Kosuga, M Tsuji, M ...1990 Volume 43 Issue 4 Pages 631-635
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSWe report a case of anal ulcers as a main symptom of ulcerative colitis.
The patient was a 59 year-old man. He was admitted to our hospital on June 8, 1989, complaining of severe anal pain.
The anal ulcers were situated at 1 and 7 o'clock. They were broad, deep and hard. They were so characteristic that we suspected the existence of an underlying disease. Syphilis, tuberculosis, leukemia and cancer were excluded from the labolatory data and the biopsy taken at anal ulcers. Finally he was diagnosed as having ulcerative colitis from the colonscopy and barium enema findings.
He was treated with IVH, injection of predonisolon and oral medication of salazopyrin. One and a half months later he obtained remission of the colon. At the same time his anal ulcers healed.
Ulcerative colitis should be added to the differential diagnosis of the anal ulcer even if abdominal symptoms are mild.View full abstractDownload PDF (6106K) -
N Matsuhashi, H Nakagama, K Sugano, F Takaku, T Muto1990 Volume 43 Issue 4 Pages 636-640
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSA 33-year-old woman with a 7-month history of ulcerative colitis refractory to oral and intravenous glucocorticoid therapy was treated with 8 mg/kg/day of oral cyclosporin. Mucobloody diarrhea disappeared within 2 weeks of the therapy, which was accompanied with marked improvements of the colonoscopic findings. After two months of cyclosporin treatment, she underwent colectomy with ileorectal anastomosis. No complication occurred. Following the operation, the cyclosporin administration was discontinued, but the inflammation of the residual rectum has well been controlled for more than 18 months with oral sulfasalazine and to mg/day of prednisolone suppository. Finger tremer, which was the only side effect of the cyclosporin treatment, was mild and required no treatments. The results suggest that cyclosporin can be used as a remission-inducing agent in patients with active ulcerative colitis, but further investigations will be necessary to clarify the effectiveness and indication of the agent.View full abstractDownload PDF (2518K) -
M Niizawa, M Itoh, T Mukojima, M Takeda, N Mizuguchi, S Suzuki, K Igar ...1990 Volume 43 Issue 4 Pages 641-644
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSA rare case of triple colon cancers with situs inversus totalis was reported. A 52-year-old woman complaining low abdominal fullness and pain was admitted to our hospital. Chest X-P revealed dextracardia. Double contrast barium enema study revealed an apple core sign in the descending colon and a depressive lesion in the transverse colon in addition to situs inversus. Colonoscopic finding revealed an advanced cancer in the descending colon, but fiberscope could not be further inserted because of narrowing due to the tumor. A moderately defferentiated adenocarcinoma was confirmed by biopsy. CT revealed a liver tumor in the right lobe in addition to situs inversus. Hemicolectomy and liver wedge resection were performed. Histology of the resected colon demonstrated an advanced colon and an early cancer in the desoending colon and an early colon cancer in the transverse colon. The resected liver demonstrated a metastatic tumor from colon cancer.View full abstractDownload PDF (4587K) -
S Shirai, S Akimoto, T Igarashi, S Kitabatake, K Watanabe, H Kohno, Y ...1990 Volume 43 Issue 4 Pages 645-650
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSThe patient, male aged 64 years old, came to our hospital with complaint of the left abdominal pain persisted for 1 year. He was then admitted under the diagnosis of desending colon cancer by barium enema Xray. A tumor, 3 cm in diameter, was found in the liver S3 area by US and CT examination, and abdominal section was performed under the diagnosis of liver metastasis. During the operation, a small tumor, 7 mm in diameter, was recognized in the margin of the liver S2 area, and then excision of lateral area of the left lobe, left hemicolectomy and cholecystectomy were performed. On the pathohistological findings, the tumor in S3, 3 cm in diameter, was hepatoma, and the tumor in S2, 7 mm in diameter, was mucinous liver metastasis cancer of desending colon cancer. A double cancer case in both colon and liver is relatively frequently encountered at autopsy but the operated case has been few. Furthermore, successful double excision has rarely been reported. This case was reposted here, because a case in which liver metastasis and hepatoma were simultaneously found and excised has never been described in the literatures concerned.View full abstractDownload PDF (7863K) -
M Hiromoto, A Yasui, Y Nishida, K Kumagai, Y Sanada, [in Japanese], K ...1990 Volume 43 Issue 4 Pages 651-655
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSThis is a case report of a cancer with high risk family disposition of colon cancer.
In a 62-years-old woman with multiple gastric carcinoma and a cancer in the ascending colon total gastrectomy and right hemicolectomy were performed. After the operation, she was found to have a rectal cancer and a renal cancer. Her husband died of a metastatic liver cancer of the biliary carcinoma. Their first son had a cancer in the sigmoid colon, and partial colectomy was performed. After the first operation, his three ascending colon cancers were found and right hemicolectomy was done. The second son died of a metastatic liver cancer after operation for his rectal cancer. The fifth son showed to have an early cancer in the discending colon. The first doughter with a history of perviously treated uterine cancer showed to have a gastric cancer.
In conclusion, the follow-up examination seemed necessary to performed every year.View full abstractDownload PDF (7855K) -
1990 Volume 43 Issue 4 Pages 656-690
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSDownload PDF (7604K) -
1990 Volume 43 Issue 4 Pages 691-766
Published: 1990
Released on J-STAGE: October 16, 2009
JOURNAL FREE ACCESSDownload PDF (18476K)
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