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Volume 50, Issue 8
Displaying 1-8 of 8 articles from this issue
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Y. Oohata, R. Mibu, T. Nakano, M. Ishikawa, M. Sakai, M. Tanaka1997 Volume 50 Issue 8 Pages 557-561
Published: 1997
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSThe effect of the conventional MagcololTM method and polyethylene glycol method (PEG, NiflecTM) on preoperative bowel cleansing was investigated using 26 patients with nonstenotic colorectal cancer. Intestinal flora was examined by saline irrigation of the rectum. The decrease in the number of bacteria after bowel cleansing and chemophylaxis tended to be larger in the PEG group than in the conventional method group, although the difference was not significant. Side effects such as nausea and abdominal pain were noted in two patients of the conventional method group but nausea was noted in only one patient of the PEG group. These data suggested that the PEG method is equally or more effective for bowel cleansing in colorectal surgery.View full abstractDownload PDF (292K) -
Y. Nishiyama, Y. Ootani, H. Mitomi, K. Yamashita1997 Volume 50 Issue 8 Pages 562-571
Published: 1997
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSHuman colonic cancer cell lines KE-24 and KE-43 cultured at our laboratory were cloned in soft agar. Three resuiting clones, A and F of KE-24 and 4 of KE-43, were transplanted in nude mice subcutaneously and intraperitoneally to evaluate their ability to form tumors. In addition, DNA extracted from the cultured cancer cells was examined by the direct sequence method for c-Ki-ras mutation, by Southern blot hybridization for DCC gene abnormalities, and by immunostaining for expression of p53 and bcl-2 proteins. Clo-nes A and F were found to be poorly-differentiated adenocarcinomas that were capable of subcutaneous tumor formation and intraperitoneal cell proliferation and were positive for DCC gene abnormalities (base insertion) and excessive expression of p53 potein. Clone 4 was found to be capable of subcutaneous tumor formation, but was a moderately-differentiated adenocarcinoma without the ability to propagate intraperitoneally and was positive for C-Ki-ras mutation (codon12 : Gly Val) alone. Different cancer gene abnormalities and abnormal cancer-related proteins were observed in cultured cancer cells of differing histological type and differing ability with respect to tumor formation and cancer cell proliferation.View full abstractDownload PDF (9697K) -
S. Yoshikawa, H. Fujii, H. Nakano1997 Volume 50 Issue 8 Pages 572-583
Published: 1997
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSThis study was designed to clarify the mechanism of disordered defecation after low anterior resection(LAR).
Twenty four patients were divided into two groups, the poor motility group (Group I), including 12 subjects who defecated over four times per day, and the good motility group (Group II), including 12 subjects who defecated under three times per day. At fist, a polyethylene-tube was inserted into the cecum usnig a colonoscope and a guide wire. 37 MBq99mTcDTPA in 50ml of tepid saline containing 5 mg of bisacodyl was infused into the cecum through the tube. Transit time and expulsion ratio from the rectum (ERr) were studied.
The average times of propelling RI-solution from the transverse colon to the descen-ding colon, from the descending colon to the rectum, and from the rectum to defecation were 37.5 seconds and 163.7 seconds, 48.7 and 293.5, 47.7 and 215.5, respectively in Group I and Group II. ERr was 84.3% in Group I and 94.5% in Group II.There are significant diffe-rences between these two groups.
Colonic transit time in Group I was shorter than that in Group II, and ERr in Group I was less than that in Group II, These results suggest that the disorded defecation after LAR may be partly caused by poor colonic motility and dysfunction of the neorectum.View full abstractDownload PDF (815K) -
J. Tsuchiya, T. Nagata, H. Kawagoe, S. Mori, S. Tachibana, T. Kajima, ...1997 Volume 50 Issue 8 Pages 584-593
Published: 1997
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSThe primaty cancer of the vermiform appendix is clinically very rare disease, and from the viewpoint of anatomical position, this symptom is not revealed until the disease becomes very advanced. The situation causes prognosis of this disease to be poor. Two cases of primary cancer of the vermiform appendix, one of pyo-hematuria caused by cancer invasion into the urinary bladber and the other of right side abdominal pain caused by cancer invasive constriction of the right ureter, were reported. The first case was treated with partial caecotomy and partial resection of the urinary bladder, including the invading tumor, and the second case was treated with ileocaecostomy together with ureterostomy ( 5cm long resection of the right ureter ) . Cancer recurred in the first patient, resulting in death. Sixty-four cases of primary cancer of the vermiform appendix reported in Japan since 1982 were referred to, and confirmed that urinary tract invasion of primary cancer of the vermiform appendix is the most frequent complication compared with invasion into other organs, that is, the cases with invasion into the urinary tract were 18.8%, the cases into the caecum and retroperitineum were 4.7% respectively and the cases into the sigmoid colon and genital organ were 3.1% respectively. The pseudomyxomatous peritonitis, a wellknown complication accompanied with the rupture of this lesion, was less frequent than urinary tract invasion, being 12.5%.View full abstractDownload PDF (7982K) -
Y. Nishiyama, Y. Ootani, Y. Hiki, A. Kakita, M. Igarashi, T. Katsumata ...1997 Volume 50 Issue 8 Pages 594-598
Published: 1997
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSA 31-year-old male with severe lower abdominal pain was reported. He had suffered bloody stool with abdominal pain for several years. A barium enema study and colonoscopic study disclosed severe stricture of the sigmoid colon. The stricture was localized in the sigmoid colon and measured 4cm in length. Segmental resection of the sigmoid colon was done to reliere obstructive symptoms. Gross findings ware localized stricture and innflammatory polyps. Histologic examination of the resected specimen disclosed regenerative and hyperplastic epithelium, cystic dilatation of colonic crypt in submucosa, transmural inflammation, and fibrosis. Granuloma was not found. Clinical, gross, and histologic findings of the case indicated that the case belongs to a new category of inflammatory bowel disease, thatis, different from known entity of inflammatory bowel disease.View full abstractDownload PDF (4498K) -
S. Shimoda, S. Koyama1997 Volume 50 Issue 8 Pages 599-604
Published: 1997
Released on J-STAGE: December 03, 2009
JOURNAL FREE ACCESSA case of 45-year-old female with diminutive, poorly-differentiated adenocarcinoma of the sigmoid colon is reported herein.
Sigmoidectomy was performed and the resected specimen had a 7-mm diameter protruded lesion with a shallow ulcer. Histologically, the tumor was largely occupied by poorly-differentiated adenocarcinoma with signet-ring cell component. The tumor was found to have extended into the subserosal tissue through the permeation of lymphatic 'vessels. Three lymph nodes were found to be replaced almost completely by metastases.
This case report was presented to enhance the awareness of the possibility that diminutive colon cancer, smaller than 1 cm in diameter, may be present in an advanced stage. Further studies are needed to fully assess the biological behavior of colon cancer.View full abstractDownload PDF (4455K) -
M. Kunimoto, K. Sasaki, K. Hirata1997 Volume 50 Issue 8 Pages 605-609
Published: 1997
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSTwo hundred fifty-one patients with internal hemorrhoids were screened by both Fecal Occult Blood Test (FOBT) and colonofiberscopic examination (CF) to investigate the relationship of internal hemorrhoids, colon disease, and FOBT positive. The rate of posi-tive FOBT in patients with internal hemorrhoids was 22.7%, which is high when compared with the results of patients who undergo regular medical checkups for colorectal cancer. Further the correlation between the degree of anal prolapse of internal hemorrhoids and the rate of positive FOBT was low by Goligher's classification IV, but it was about stan-dard in I-III. After negative results were obtained by colonofiberscopic examination, 46 (20.4%) out of 226 cases were FOBT positive in patients having internal hemorrhoids.
On the other hand, in cases where the FOBT was negative, cancer or polyps were found in the large intestine of patients having internal hemorrhoids. Therefore it was suggested that testing for both FOBT and CF is very important.View full abstractDownload PDF (280K) -
1997 Volume 50 Issue 8 Pages 610-651
Published: 1997
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSDownload PDF (3248K)
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