All issues
Predecessor
Volume 46, Issue 2
Displaying 1-17 of 17 articles from this issue
- |<
- <
- 1
- >
- >|
-
Analysis by Age, Sex, and Size or Shape of the Large BowelS. Sadahiro, T. Ohmura, Y. Yamada, T. Saito, Y. Taki1993 Volume 46 Issue 2 Pages 111-115
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSRelationships between age, sex, length and surface area of the whole large intestine, and number of loops formed by the sigmoid colon and frequency of defecation were analyzed in 920 patients who underwent barium enema in order to study factors affecting bowel habits. The frequency of defecation was once or twice per day in 67.8 % and 53.6 % of male and female patients, respectively, and the frequency in 77.6 % of male patients and 71.9 % of female patients ranged from two times per day to once per three days. The frequency of defecation decreased with aging, leading to an increase in the frequency of laxative use in male patients, while there was no relationship between age and frequency of defecation or laxative use in female patients. In both sexes, when length and surface area of the whole large intestine measured and calculated on barium enema roentgenograms were long and large respertively, the frequency of defecation decreased, leading to a increase in the frequency of laxative use. The length and surface area of the whole large intestine were found to be closely connected with bowel habits. There was no correlationship between number of loops of the sigmoid colon and the frequency of defecation.View full abstractDownload PDF (332K) -
K. Okuyama, T. Awano, H. Matsubara, N. Tohnosu, Y. Koide, T. Nagasima, ...1993 Volume 46 Issue 2 Pages 116-122
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSChoice of hepatic resection for colorectal cancer patients with liver metastases was studied in the effectiveness to improve survival. 115 patients with synchronous liver metaseases and 64 patients with metachronous were examined. In synchronous liver metastases, 5-year survival of primary tumor resection with hepatic resection (n=36) was 26.9 %, showing significantly superior to primary tumor resection with chemotherapy (n=58) and primary tumor resection alone (n=13). In Hi liver metastases, 5-year survival of primary tumor resection with hepatic resection (n=28) was 30.7%, revealing significantly favorable compared to primary tumor resection with chemotherapy (n=7). However, no significant differrence was seen between the two therapy group in H2 liver metatsases. It was found that solitary lesion (n=17) was significantly superior in survival to multiple lesion (n=11) in H1 liver metastases (44.2% vs 22.2%). In addition, 5-year survival of tumors under 4cm in size (n=10) (75%) was found to be more favorable than that of over 4 cm in solitary lesions. W hearas, in metachronous liver metastases, 5-year survival of hepatic resection (n=30) was 17.4 % and there was significant differrence compared to non hepatic resection (n=34). However, no significant differrence was seen in size and number of metastases. Thus, we concluded that hepatic resection was specificaly effective to improve survival of synchronous H1 liver metastases with solitary lesions smaller than 4cm in size.View full abstractDownload PDF (382K) -
M. Itabashi, S. Yamanaka, T. Shiratori, A. Moriuti, S. Kameoka, K. Ham ...1993 Volume 46 Issue 2 Pages 123-128
Published: 1993
Released on J-STAGE: December 03, 2009
JOURNAL FREE ACCESSA 78-year-old women with the characteristic clinical and pathological picture of Cronkhite-Canada Syndrome associated with sigmoid colon cancer is presented.
Upper gastrointestinal endoscopy revealed nearly total replacement of gastric mucosa by numerous polyps. Biopsy specimens of these polyps showed hyperplastic glands without atypia and edematous stroma with inflammatory cell infiltration.
Barium enema study revealed sigmoid colon cancer and semipedunculated polyps. Colonoscopic biopsy was performed for these lesions. Histological findings showed adenocarcinoma and tubular adenomas with mild atypia.
According to our research, fifteen cases of Cronkhite-Canada syndrome associated with colon cancer have been reported in Japan. W e added here a case of such a rare condition to the literatures.View full abstractDownload PDF (2975K) -
A Comparison with the Ulcerating Type, SubtypesH. Masuda, S. Hayashi, Y. Nakamura, H. Horiuchi, K. Watanabe, I. Hayas ...1993 Volume 46 Issue 2 Pages 129-135
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSDuring the 10 years from Jan 1982 to Dec 1991, 50 cases with protuberant advanced carcinoma of the large intestine were resected in our department.
These 50 cases were compared with 530 cases which were designated as ulcerating type (Borrmann 2, 3). Furthermore, the 50 cases with protuberant type were classified into 4 subtypes. In comparison with the ulcerating type, the protuberant type had characteristics including a lower incidence of lymph node and liver metastasis, higher ratio of cases limited within the pm layer, less invasion of vessels and a better prognosis. Among the protuberant type, the nodular protuberant type was the most common. The flat type with noduli had features of a higher incidence of lymph node metastasis and lymphangial invasion. However, the flat type with noduli had a good prognosis since most cases in this type were limited within the pm layer. Conversely, the nodular type with fissures tended to have a poor prognosis. We think that classifying the protuberant type into 4 subtypes is very important in recognizing the characteristics of protuberant advanced carcinoma of the large intestine.View full abstractDownload PDF (1701K) -
T. Imamura, M. Okada, M. Seo, T. Yao1993 Volume 46 Issue 2 Pages 136-146
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSThe comprehensive surgery was carried out to evaluate the quality of life (QOL) from April 1990 to June 1990 in 106 patients with Crohn's disease of which 90% was outpatients. The average follow up period from the onset was 6.8±4.9 years (Mean±SD). The results were as follows ; 1) Fourteen percents of those surveyed were unable to work during the last one year ; 2) 64% of those who subscribed to life insurance had been turned down ; 3) 50% of patients suffered abdominal pain, diarrhea, frustration, worried over falling sick in the future and complained of limitations of sports or leisure activitieds in the last one month.
Self-evaluation of degree of satisfaction of living life, with 11 scale method during the last one month (Subjective QOL) in which 0 is worst QOL and 10 is best QOL, was made. The average score was 6.2±2.4 (Mean±SD) and 55% of total cases belonged to score 5 to 7. Multiple stepwise regression analysis was carried out to elucidate factors influencing subjective QOL, in which sex, age, the presence of complications, history of surgical operations, labolatory data, bowel symptoms, systemic symptoms, emotional function and social function in addition to items above mentioned were used as independent variables. As a result of multivariate analysis, limitations of sports or leisure activities, sex (men are worse than women in QOL) and frustration were turned out to be significant associations between subjective QOL and many factors in univeariate analysis.View full abstractDownload PDF (787K) -
K. Morise, T. Yamaguchi, A. Kuroiwa, Y. Horiuchi, A. Furusawa, K. Kana ...1993 Volume 46 Issue 2 Pages 147-159
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSWe have developed a new method to measure quality of life (QOL) for patients with inflammatory bowel disease (IBD). Following a preliminary questionnaire containing 50 questions in 21 IBD patients, a self-administered form of questionnaired was developed. This form contained 220 questions covering various dimensions such as symptoms, home life, economic anxiety, social impairment, emotional function and face scale, with which QOL was evaluated in 51 ulcerative colitis (UC) patients and 42 Crohn's disease (CD) patients. Both of UC and CD patients in active stage had significantly worse scores in each dimension than those in remission. Furthermore, in remission, CD patients tended to show worse profiles. than UC patients in appetite, mood, anxiety for work or house affairs, and economic anxiety. The QOL score showed a negative correlation with the State-Trait anxiety Inventory and Self-Rating Depression Scale..
We conclude that the evaluation of QOL offers important information in the treatment of IBD patients.View full abstractDownload PDF (673K) -
N. Saitoh, H. Sarashina, M. Nunomura, H. Nakayama, T. Ohmori, K. Kohda ...1993 Volume 46 Issue 2 Pages 160-168
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSOne hundred and eighty-five cases with 191 lesions of early colorectal cancer were analyzed clinicopathologically to asses the tharapuetic plan.
The sm cancers were divided into two categories-sm-slight and sm-massive-according to the degree of cancerous invasion in submucosa. The sm1 was defined as the sm-slight, the sm2 and sm3 as the sm-massive. The sm-massive cancers had more vessel invasion and mode-rately or poorly differentiated carcinoma than the sm-slight statistically. The lymph node metastasis was shown in the sm-massive group.
The sm-massive cancers were high risk group for metastasis or recurrence, and the sm-slight has the same histological feature as the m cancers. The sm-massive cancers should be treated by segmental resection with regional lymph node dissection.
The m and sm-slight cancers should be treated initially by endoscopical therapy or local excision. Therefore it seems to be very important to judge m and sm-slight or sm-massive cancer preoperatively using findings of biopsy, EUS and magnifing endoscope.View full abstractDownload PDF (1645K) -
N. Yasuda1993 Volume 46 Issue 2 Pages 169-174
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSInhibitory effects of orally administered OK-432 on the growth of DMH-induced colon tumors in rats were examined. Rats were classified in four groups according to the dose of OK-432 (OK-432 0KE, 0.5KE, 2.0KE, 5.0KE). Barium enema was performed after 26th and 30th week of DMH-treatment. 2.0KE group showed the longest tumor doubling time (p<0.05). The evaluation of tumor growth by tumor doubling time seems to be resonable and in this respect, oral administration of OK-432 2.0KE had preventive effects on the growth of tumors. The effect was not correlated whth the dose of OK-432.View full abstractDownload PDF (2878K) -
H. Kurihara, H. Mochizuki, K. Hase, S. Yokoyama, K. Yoshimura, T. Yama ...1993 Volume 46 Issue 2 Pages 175-181
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSEight hundred and forty-nine colorectal cancer patients, who received tumor resection in our hospital from 1978 to 1991, were examined. The maximum diameter of the tumor was classified into three groups: ‹30mm (group S), 30-80mm (group M), ›=80mm (group L).
Group S accounts for 12 % of all patients, group M 74 %, group L 14 %. Pathological features such as degree of circumferential involvement, invasive shape of tumor, depth of invasion, pathological stage got worse according to tumor size. Liver metastasis, vessel invasion and histological type (wel. mod. por.) were better in group S than group M and L. Peritoneal dissemination and distant metastasis were worse in group L than group S and M. The same was the rate of curative resection, namely, group L showed apparently the worse rate (49 %), whereas group M showed 71 % and group S 91 % (P<0.0001). As tumor size became greater, cumulative 5 year survival rate got worse (S 76 %, M 52 %, L 41 %: P<0.0001). When the tumor was resected curatively, the rates of 5 year survival were almost the same among all groups (S 80 %, M 70 %, L 68 %). However, positive cancer cell infiltration on the surgical margin, as a factor by which patients were succumbed to palliation, was the most frequent in group L. Group S revealed the lowest ratio of tumor recurrence after curative resection (S 6 %, M 22 %, L 15 % : P<0.001).
In conclusion, the new classification of tumor size seemed to be useful for preoperative prediction of postoperative prognosis.View full abstractDownload PDF (455K) -
T. Miwa, F. Yamada, M. Yamauchi, T. Kondo, [in Japanese], T. Okada1993 Volume 46 Issue 2 Pages 182-186
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSSigmoidscopic medical check-up of the asymptomatic 1989 cases were done in our hospital for the last two years. We found 9 colorectal cancer (0.5%), 311 polyps (15.7 %), 2 carcinoid The pathologic diagnoses of 282 polyps were. obtained: 165 (58.5 %) were tubular adenoma, 82 (29.1 %) hyperplartic polyps, 5 (1.8 %), villous adenoma, and 6 (2.1%) adenocarcinoma. The. occult blood of the stool was examined at the, same time. Of 9 colorectal cancer cases, only 4 were positive and the other 5 revealed negative.
In screening the colorectal cancer, the endoscopic examination was highly-more effective and recommendable than the, occult blood test of the stool.View full abstractDownload PDF (294K) -
K. Watanabe, Y. Kohata, N. Shimizu, K. Sasaki, M. Igawa, K. Tsuchiya, ...1993 Volume 46 Issue 2 Pages 187-193
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSThis study was undertaken to examine the effect of change of fecal intestinal flora, tumors growth and inhibitory in rats.
Twenty-five 6-week-old rats of Sprague-Dawley series were orally given Bifidobacterium brebe and Transgalactosylated Oligosaccharides (TOS). Selectively Bifidobacterium was increased Bif(+) group and Bif(-) group were divided for study. At 36th week the 13 alived ones were slaughtered. The entire colon was cut for histopathological study. Identification and quantification of fecal intestinal flora before the experiment and slaughter were performed. Growth number and frequency of advanced cancer and percentage of advanced cancer in all cancer lesions showed significant low rate in Bif(+) group. Both early and advanced cancers had a tendency of small size. Growth number and frequency of a typical grandular tubule were high in Bif(+) group. Mild degree atypical glandular tubule was only seen in Bif(-) group and moderate and severe degree were high in Bif(+) group.
From the above results, it is suggested that Bifidobacterium has a possible relation to change of intestinal flora and growth, advancement and inhibition of colon cancer.View full abstractDownload PDF (2266K) -
H. Iwagaki, A. Hizuta, S. Kimura, Y. Nonaka, M. Nezu, M. Marutaka, S. ...1993 Volume 46 Issue 2 Pages 194-197
Published: 1993
Released on J-STAGE: March 03, 2010
JOURNAL FREE ACCESSIn this study, the authors have examined the effects of lactosucrose (LS) administration peroral on the changes in the intestinal microflora in a patient with familial polyposis coli. A 28-year-old woman has been suffering from bowel habit disorders after total proctocolectomy and ileoanal anastomosis which were performed 10 years before. LS was orally administered to the patient. Intestinal microflora, fecal pH, fecal moisture, fecal organic acid were analyzed before and after administration of LS. After administration of LS, the fecal moisture downed to the normal range and the. fecal pH decreased due to the increase in lactic acid content of feces. In terms of intestinal microflora, Bacteroidaceae was prominent before LS administion, however, after LS administration marked increases in Bifidobacterium, Streptococcus and Peptococcaceae count ratios were observed. These findings indicate that oral administration of LS which is selectively used by Bifidobacterium is able to normalize the abnormal intestinal microflora in postcolectomy patients who are suffering from diarrhea leading to oligotrophia, and its clinical application is expected.View full abstractDownload PDF (243K) -
M. Sakatoku, T. Arakawa, M. Kosugi, H. Nakajima, Y. Annen1993 Volume 46 Issue 2 Pages 198-201
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSA case of small advanced sigmiod colon cancer whose origin was suggested to be a superficial tumor type II a was experienced. A 77-year old woman complaining abdominal pain visited the hospital. Colonoscopy showed reddish flat elevated lesion with fold conversion and spontaneous bleeding in the sigmoid colon. Endoscopically, it was considered that the carcinoma invaded massively into the submucosal layer or deeper. And sigmoidectomy was performed. Resected specimen showed a flat elevated lesion like superficial carcinoma type II a, and the lesion measured 10mm in diameter. Histological diagnosis was moderately differentiated adenocarcinoma, and cancer cells invaded into the subserosal layer with-out lymphnode metastasis.View full abstractDownload PDF (4120K) -
S. Suzuki, T. Igarashi, K. Watanabe, T. Hayashi, K. Yoshida, K. Akiyam ...1993 Volume 46 Issue 2 Pages 202-206
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSWe present a case of primary malignant lymphoma of the ileum diganosed preoperatively. A 22-year-old woman, who had intermittent epigastralgia, nausea and right lower quadrant pain, visited our hospital. The wall hypertrophy of the terminal ileum, swelling of the regional and the large abdominal superficial lymph node of the right side were detected with ultrasonographic examination, then she was admitted. Malignant lymphoma was detected with ultrasonographic examination, then she was admitted. Malignant lymphoma was suspected by the X-ray study of the small intestine, endoscope and computed tomography. The right hemicolectomy, partial ileum resection and the lymph nodes dissection for the superior mesenteric artery region were performed. Because primary malignant lymphoma of the small intestine was difficult to diagnose preperatively, the prognosis was poor. The 5 year survival rate was 22-40% and was different to each clinical stage, curative operation. Therefore it was important to diagnose clinical stage with the systematic examination preope-ratively.View full abstractDownload PDF (4183K) -
M. Kato1993 Volume 46 Issue 2 Pages 207-210
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSA 16-year-old woman underwent Gant-Miwa operation with Thiersch wiring due to complete rectal prolapse. But, on the eighth postoperative day, she complained suddenly severe abdominal pain on -defecation. An operation was performed immediately, because of a suspected perforation of the colon. At laparotomy, a perforation on the anterior wall of the rectosigmoid junction was found out. The perforation was diagnoted a complication following Gant-Miwa operation, because of the perforation on a just oral side of an operative scar with Gant-Miwa operation.
Primary suture-closure was performed, then, the peritoneal cavity was lavaged with 5000ml saline.
The postoperative course was quite uneventful. As the severe complication of perforation of the colon following Gant-Miwa operation, without reporting in Japan, was experienced, I reported.View full abstractDownload PDF (1307K) -
K. Nakagawa, S. Momono1993 Volume 46 Issue 2 Pages 211-214
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESSThe case is sixty-seven years old, female. Thirty-one months ago, a soybean-size black tumor was palpated at the anal orifice, but the tumor was ligated by her home doctor. She visited us because of the recurrence of the tumor. The tumor existed at the posterior wall of the anus and the size was of a walnut. The ultrasonographic examination disclosed that the inside echo of the tumor was not uniform and the tumor had obscure border and the size of the tumor was 5.0 X 4.2 X 3.8 cm. Similar findings were obtained by a CT-scan. Since it was diagnosed as malignant melanoma after performing needle biopsy, we first suggested that abdominal perineal resection followed by extensive resection of the lymph node should be performed. As the patient refused the procedure and no metastasis was found after performing transabdominal needle aspiration of retroperitoneal lymph node and also percutaneous aspiration of the inguinal lymph, local resection of the rectum via the anal sphincter was performed. Postoperatively, DAV therapy was performed and interferon was also administered as immunochemical treatments. At present, five months after the operation, no findings suggesting the recurrence were observed and noticed.View full abstractDownload PDF (2949K) -
A. Tsunoda, M. Kawamura, K. Nakao, H. Yoshizawa, T. Kawaguchi, K. Maru ...1993 Volume 46 Issue 2 Pages 215-218
Published: 1993
Released on J-STAGE: June 05, 2009
JOURNAL FREE ACCESS210 patients had curative resection for primary colon cancer between 1980 and 1989. Three patients had a suture-line recurrence (1.4%). The primary tumors were all in the sigmoid colon and length of normal bowel resected below the tumor was 5-10cm. S depth of invasion, n1 (+) lymphnode metastasis with ly2-ly3 lymphatic invasion were found in those specimens. In second resected specimens, depth, of invasion was s in two and pm in one. Lymphnode metastasis was found in one. Factors contributing to the suture-line recurrence were discussed.View full abstractDownload PDF (1604K)
- |<
- <
- 1
- >
- >|