Background: The rate of perineal wound complications associated with abdominoperineal resection (APR) and total pelvic exenteration (TPE) is high. Negative pressure wound therapy (NPWT) involves the controlled application of sub-atmospheric pressure to promote wound healing in a closed environment and has been effectively used for intractable wounds. The aim of this study was to investigate the effect of NPWT in preventing perineal wound complications.
Patients and Methods: Between September 2014 and January 2016, 16 patients who were treated with NPWT for perineal wounds were evaluated.
We retrospectively evaluated the patients' background and the rate of perineal wound complications, in comparison with 111 patients who were treated without NPWT.
Results: The population undergoing neoadjuvant chemotherapy and laparoscopic surgery was higher in the NPWT group and blood loss was more in the NPWT negative group. Wound dehiscence and surgical site infection (SSI) were seen in 11 patients (10%) and 36 patients (32.4%) in the NPWT negative group, respectively. On the other hand, in the NPWT group, there was no wound dehiscence and SSI was seen in only 2 patients (12.5%).
Conclusion: NPWT may be useful to decrease perineal wound complications in APR and TPE.
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