Nihon Daicho Komonbyo Gakkai Zasshi
Online ISSN : 1882-9619
Print ISSN : 0047-1801
ISSN-L : 0047-1801
Volume 58, Issue 7
Displaying 1-8 of 8 articles from this issue
  • W. Daiko, N. Saito, S. Kameoka
    2005 Volume 58 Issue 7 Pages 377-382
    Published: 2005
    Released on J-STAGE: March 03, 2010
    JOURNAL FREE ACCESS
    Purpose : In this study, transforming growth factor-β1 (TGFβ31), which has attracted attention as a growth factor of malignant tumor in recent years, was analyzed immunohistologically and serologically in patients having operation for colorectal cancer, and its clinical significance as a malignancy factor was examined.
    Subjects and Methods : On 72 patients who underwent operation for colorectal cancer in this department, immunohistological staining was performed using anti-TGF-β1 antibody. Serum TGF-β1 level was measured in these cases together with 25 non-cancer cases, a total of 97 cases. Results : In immunohistological staining, the positive rate became higher in lymph-node metastases and in progressing invasion into the vascular system. In serological examination, a significant difference was found between cancer cases and non-cancer cases, and TGF-β1 level rose with progressing liver metastasis and venous invasion.
    Conclusion : In colorectal cancer, TGF-β1 seemed to be usable for predictive evaluation of malignancies such as hematogenous metastasis preoperatively.
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  • S. Uchiyama, M. Kokuma, H. Yamamoto, T. Sigemitu
    2005 Volume 58 Issue 7 Pages 383-387
    Published: 2005
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    A case of a rectal oleogranuloma (OG) caused by long-term use of ointment for hemorrhoids is reported. A 64-year-old man, who had undergone the Whitehead-operation 15 years previously, but had not received any injection treatment for hemorrhoids, was introduced to my clinic because of difficulty in passing stools in October 2001. Prior to the first consultation, he had used an ointment once a day for 21 months because of prolapse and bleeding of his hemorrhoids. He had experienced pain in using the ointment and difficulty in passing stools since September 2001. Digital examination showed a 3-cm elastic submucosal tumor in the left anterior wall and a prolapsed hemorrhoid in the opposite site of the anus. A semiclosed hemorrhoidectomy was performed, and rectal biopsies of the tumor were taken. The histological findings of the tumor specimens showed an oleogranuloma, and so use of the ointment was stopped without any further resection of the mass. Postoperative computed tomography taken two months later showed that the tumor had shrunk markedly, and his symptoms improved. At a recent consultation in October 2004, digital examination revealed that the mass had reached a size of less than 1cm in diameter, and the patient was symptom-free. To our knowledge, eight cases of rectal OG caused by suppository and/or ointment have been reported. We discuss the site and the size of 25 cases of rectal OG., including the above-mentioned eight cases.
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  • Y. Kabeshima, T. Kageyama
    2005 Volume 58 Issue 7 Pages 388-391
    Published: 2005
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    A 67-year-old woman was admitted to our hospital for examination and treatment of a cervical carcinoma. A colonofiberscope study was done and revealed a lateral spreading tumor 20 nun in diameter on the semilunar fold in the transverse colon. We diagnosed this as adenoma. We tried snaring by the endoscopic mucosal resection method, but it was impossible because of non-lifting sign and its location. We therefore tried the Hook-knife EMR method (endoscopic submucosal dissection, ESD). We cut the mucosa around the lesion with the Hook-knife and the submucosal tissue, and then an en-block resection was done successfully. No complication was observed in this procedure. Histological examination showed tubular adenoma with severe atypia, and the cut end was free of adenoma.
    We consider this is a good indication for lesions such as non-lifting sign tumor because of scar, etc., or the cecum and ascending colon for which it is sometimes difficult to perform a strip biopsy. This method al-lows en-block resection to be performed successfully.
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  • K. Abe, Y. Shinohara, K. Ueda, T. Katakami, M. Miyaoka, M. Mochizuki
    2005 Volume 58 Issue 7 Pages 392-396
    Published: 2005
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    A 61-year-old man was admitted to our hospital on December 3, 2002 with a one-month history of epigastric pain. He had a past history of hypertension, stomach ulcer and appendectomy. The family history was not significant. An upper gastrointestinal series and barium enema examination revealed a niche at the angulus on the lesser curvature of the stomach and polyps in the sigmoid colon and rectum. Colonoscopy examination revealed polyps in the sigmoid and descending colon and a subpedunculated lesion in the rectum, 11 mm in diameter, that was similar to the mucosal color but had a depression at the top of the lesion. Endoscopic ultrasonography (EUS) demonstrated a hypoechoic lesion with hyperechoic spots in the submucosa. When a biopsy failed to confirm the definite diagnosis of the lesion, it was removed for diagnosis and treatment, and a diagnosis of rectal carcinoid was made. In cases with relatively high internal echoes, the amount of fibro-interstitium exceeded that of tumor cells histologically.
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  • K. Narui, Y. Yamazaki, T. Suda, H. Ike, H. Shimada
    2005 Volume 58 Issue 7 Pages 397-401
    Published: 2005
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    A 59-year-old woman visited our hospital in December 2001 because of abdominal distention. Barium enema and colonoscopy showed a tumor of the transverse colon and from the biopsy adenocarcinoma was diagnosed histologically. She was admitted to our hospital as an ambulance call in February 2002 because of bowel obstruction. We diagnosed colon obstruction by the transverse colon cancer and operation was performed. During the operation, intussusception of the transverse colon with partial necrosis of the strangulated colon was identified, and a right hemicolectomy including the necrotic colon was performed without repositioning. Intussusception in adults by cancer is relatively rare, but should be considered when a case with advanced colon cancer is encountered.
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  • M. Ota, S. Yamaguchi, H. Morita, M. Ishii, S. Osada
    2005 Volume 58 Issue 7 Pages 402-406
    Published: 2005
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    Aim : The aim of this study was to clarify the outcome of a new method of postoperative incision care without using sterile forceps or disinfectants.
    Patients and Method : From September 2002 to March 2004, 411 patients underwent SSI classification I or II operations at our institution. Most of these were primary or recurrent colorectal cancer patients. Postoperative incision care was performed manually using non-sterilized gloves, and disinfectants were not applied on the incision.
    Results : 39 patients (9.5%) developed wound infection after surgery. Multivariate analysis revealed that the operator was the only significant risk factor (p=0.005). Patients who developed wound infection, on average, stayed one day longer in the hospital compared with patients without infection. Enterobacteria were detected at the infected site, and most of the cases had no sensitivity toward surgical antimicrobial prophylaxis.
    Conclusion : Postoperative incision care could be performed feasibly with non-sterilized gloves in class I or II patients.
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  • S. Aoi, T. Shimotake, T. Tsuda, Y. Sasaki, Y. Kubota, O. Kimura, E. De ...
    2005 Volume 58 Issue 7 Pages 407-410
    Published: 2005
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    In this paper, the authors examined the possible correlation between massive fecal mass removal methods and abdominal plain X-ray film findings in 21 children with encopresis. Fecal masses in these patients were often so hard as to be difficult to remove through the anus. They were treated by the following effort-making fecal mass removing methods : i) glycerin enema, ii) repeated distal colonic irrigation, iii) repeated colonic irrigation and glycerin enema with high pressure, and iv) repeated breaking into small pieces using forceps. In this study, the patients often required hospitalization to undergo removal methods ii) to iv) typically in cases whose X-ray films showed measured maximal colonic diameters greater than 5.5 cm. Encopresis patients in childhood, whose colonic diameters measure greater than 5.5 cm, should be considered for hospitalization to undergo difficult fecal removal and subsequent detailed examination for possible intestinal motility disorders.
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  • 2005 Volume 58 Issue 7 Pages 411-414
    Published: 2005
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    Download PDF (155K)
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