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Volume 83 (2006)
- Issue 4 Pages 97-
- Issue 3 Pages 73-
- Issue 2 Pages 35-
- Issue 1 Pages 1-
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Volume 83, Issue 4
Displaying 1-4 of 4 articles from this issue
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Yutaka KOHATA, P.D. GUPTA, Fumioki YASUZUMI2007 Volume 83 Issue 4 Pages 97-106
Published: 2007
Released on J-STAGE: October 23, 2007
JOURNAL FREE ACCESSThree dimensional structure of developing ovarian fo1licles in the cat and the mouse were examined to clarify the cellular and the extra cellular components during follicular maturation by scanning electron microscopy. Epithelial cells of the membrana granulosa (MG) and the cumulus oophorus (CO) show variable morphology, which depends on the location of the cells in the follicle. In the small antral follicle, there is no morphological difference between the surface structure of the MG and the CO lining cells. in the large antral follicle, however, the lumenal lining cells of the MG change their spherical shape to a rather flattened one showing numerous pseudopodial processes ereeping over the surrounding lumenal cells. The CO cells remain rounded with fine cytoplasmic protrusions on their outer surfaces which seem to make a network. The outer surface view of the zona appears as composed of labyrinthine canals with relatively large pores of various sizes, however, the inner surface is rather compact with a number of small pores.View full abstractDownload PDF (709K) -
Xianfeng YAO, Huayue CHEN, Shoichi EMURA, Norihiro OTAKE, Shizuko SHOU ...2007 Volume 83 Issue 4 Pages 107-114
Published: 2007
Released on J-STAGE: October 23, 2007
JOURNAL FREE ACCESSAlthough human parathyroid hormone (1-34) [hPTH (1-34)] was reported to improve osteoporotic bone loss, little is known about the anti-osteoporotic effect of the traditional Chinese medicine, Gosha-jinki-gan (GJG). The purpose of this present study was to clarify and compare the effects of hPTH (1-34) and GJG on trabecular bone microarchitecture in ovariectomized (OVX) rat tibia by using microcomputed tomography (micro-CT). Thirty 2-week old Sprague-Dawley female rats were underwent ovariectomy (OVX) or sham operation. Four weeks later, the ovar iectomized rats were further divided into OVX, OVX + PTH, and OVX + GJG groups. hPTH (1-34) was administered subcutaneously at a dose of 20 pg/kg, 3 times/week, and OVX + GJG group received 0.05% aqueous solution of GJG as the only drinking fluid for 8 weeks respectively. The three-dimensional (3D) trabecular microarchitecture of the bone in the proximal tibial metaphysis was evaluated by micro-CT. in the OVX + PTH group, trabecular bone volume (BV/TV), number (Tb.N) and thickness (Tb.Th) were significantly increased, structure model index (SMI) and trabecularbone pattern factor (TBPf) decreased when compared with the OVX group. In comparison to the OVX group, BV/TV and Tb.N were signifficantly greater, while SMI and TBPf had no marked changes in the OVX + GJG group. These results suggest that the administration of hPTH (1-34) restore the trabecular bone volume and improve the microstuctural property as well, while GJG reduce the bone loss without affecting its microstructural property in ovariectomized rats.View full abstractDownload PDF (300K) -
Norihiro OTAKE, Huayue CHEN, Xianfeng YAO, Shizuko SHOUMURA2007 Volume 83 Issue 4 Pages 115-122
Published: 2007
Released on J-STAGE: October 23, 2007
JOURNAL FREE ACCESSThe collateral ligaments of the knee are important in maintaining knee stability. Numerous studies have been described the morphology and function of the ligaments of the knee. However, little data was given about the lateral and medial collateral ligaments simultaneously. The objective of the present study was to compare the morphology of the lateral (LCL) and medial (MCL) collateral ligaments in human knees. We dissected 34 cadaver knees and examined the size, attaciment and inclination of the LCL and the MCL. in both of them, the posterior bundle was longer than that of the anterior bundle. The anterior and posterior bundles of the MCL were longer than that of the LCL. The proximal attachment of the MCL situated more anterior and superior than that of the LCL. As compared with the LCL, the distal attachment of the MCL located a little forward and inferior. The longitudinal diameter of the attachment of ligaments was longer than the transverse one, except for the proximal attachment of the MCL. The size of the attachments of the MCL was larger than that of the LCL except for the longitudinal diameter of the proximal attachment. At full extension of the knee, the inclination of the MCL was backward, while that of the LCL was forward. These data showed that the LCL and MCL had the different structural properties. It may provide a better understanding of the function of the collateral ligaments.View full abstractDownload PDF (304K) -
Tat Wei TAY, Bibin Bintang ANDRIANA, Maki ISHII, Ehn Kyoung CHOI, Xiao ...2007 Volume 83 Issue 4 Pages 123-130
Published: 2007
Released on J-STAGE: October 23, 2007
JOURNAL FREE ACCESSMono(2-ethylhexyl) phthalate (MEHP) is a well-characterized testicular toxicant. in this study, morphological alterations of mice testes caused by repeated administrations of MEHP were examined by light and transmission electron microscopy. Prepubertal male mice were given a range of MEHP doses (600-900 mg/kg/day) for 3 consecutive days in corn oil by oral gavage. Control animals were given only corn oil. Thereafter, the testes were excised, fixed in 4% paraformaldehyde for light microscopy and/or 5% glutaraldehyde for transmission electron microscopy. Then, they were embedded, and sectioned. TUNEL analysis was done to quantify the occurrence of apoptosis in the testis. Cellular damages were also observed. Results showed that administration of 700 mg/kg of MEHP caused a signifficant increase in TUNEL-positive cells. At the same time, mice treated with higher doses of MEHP showed presence of degenerating (apoptotic and necrotic) spermatogenic cells. Appearance of small vacuoles in the Sertoli cell cytoplasm and displacement of spermatogenic cells were also observed. Sloughed and shed spermatogenic cells found in the tubular lumen were identified to be necrotic and apoptotic in appearance, respectively.View full abstractDownload PDF (485K)
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