Recent researches support the longer and adequate working lives contribute the health of aged workers amid policy concerns about the costs of social welfare. Some comprehensive researches showed activity theory that older adults who quit from full-time jobs deteriorated both mental health. In the field of occupational health, proper placement, keep the work ability and employability considering the individual neurophysical status, along with preventive action for workers in workplace. In many cases, working is an effective way of social participation for older people and keep the health status better over in Japan. Neurovegetative researches with a viewpoint of labour science and occupational health can find out the evidence which contribute the good practice for happiness and health of aged workers especially using data science methods.