巻号一覧
39 巻, 4 号
通巻224号
選択された号の論文の11件中1～11を表示しています
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解説
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森田 光洋, 工藤 佳久1999 年 39 巻 4 号 p. 211-216
発行日: 1999/07/25
公開日: 2000/04/12
ジャーナル フリーThe properties of glial cells are overviewed. The word of glia covers all the non-excitable cells in nervus system and consists of astrocyte, oligodendrocyte, Schwann's cell and microglia. The physiological function of glial cells has been considered to be restricted to long term neuronal function such as physical protection of neurons and metabolism, but recent development of Ca imaging technology revealed the dynamic change of glial ghysiology and the relationship of glial cells to the central problems in neuroscience such as synaptic transmission and its plasticity. Cell culture system has been the main approach to glial cell function, but the development of technology to access the glial cell property in neuronal tissue is in progress.抄録全体を表示PDF形式でダウンロード (133K) -
佐藤 智1999 年 39 巻 4 号 p. 217-222
発行日: 1999/07/25
公開日: 2000/04/12
ジャーナル フリーEndocytosis is involved in information-processing in many cell types. Recent research efforts revealed its regulatory mechanism at the synaptic terminus and regulated internalization of many G-protein coupled receptors and cell adhesion molecules. Moreover, an important break-through has been brought about by establishment of the usage of actin-dependent mechanisms. The drasitic advance in understanding of the molecular mechanism is now widening its biological significance as the global linkage among membrane traffic, cytoskeletal dynamics and signal transduction.抄録全体を表示PDF形式でダウンロード (343K)
総説
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西山 宗一郎, 本間 道夫, 川岸 郁朗1999 年 39 巻 4 号 p. 223-228
発行日: 1999/07/25
公開日: 2000/04/12
ジャーナル フリーThermotaxis in Escherichia coli as a model system for studying thermosensing mechanisms. All the components involved in the signal transduction circuit have been indentified. Thermosensors are the transmembrane proteins that were originally indentified as chemoreceptors. They regulate the activity of the cytoplasmic histidine kinase CheA. Recent studies revealed some unique and unexpected features of these "thermometer proteins", including effects of receptor covalent modification on thermosensing properties, and uncoupling of intra- and extracellular domains under some conditions. Investigation of thermosensing properties of the sensors should also be required for understanding their chemosensing mechanisms.抄録全体を表示PDF形式でダウンロード (171K) -
関本 謙1999 年 39 巻 4 号 p. 229-234
発行日: 1999/07/25
公開日: 2000/04/12
ジャーナル フリーThe energetics in the world of fluctuation is prerequisit for understanding the fundamental mechanism of a single motor protein, since the average and macroscopic descriptions in terms of thermodynamics, statistical mechanics or reaction rate are inadequate. We try to reconstruct the macroscopic concepts such as heat, chemical potential, and control in the world of fluctuation.抄録全体を表示PDF形式でダウンロード (126K) -
瀧口 陽子, 伊藤 知彦, 宝谷 紘一1999 年 39 巻 4 号 p. 235-239
発行日: 1999/07/25
公開日: 2000/04/12
ジャーナル フリーTo examine the relationship between the growth polarity of microtubules and guanine nucleotide dependence, we polymerized microtubules from axonemes either with GTP or with GTP and GDP, and observed individual microtubules by dark-field microscopy. We used a perfusion chamber to monitor the growth polarity of microtubules from the same axoneme. Exchanging a solution containing only GTP for one containing GTP and GDP elicited a switch in the growth polarity of microtubules from the plus ends to the minus ends. These results suggest that GDP directly affects microtubule polymerization and inverts growth polarity, probably by inhibiting growth at the plus ends.抄録全体を表示PDF形式でダウンロード (245K) -
濱崎 直孝1999 年 39 巻 4 号 p. 240-245
発行日: 1999/07/25
公開日: 2000/04/12
ジャーナル フリーThe current prevalent consensus of membrane proteins is that the transmembrane peptide portions have always been regarded as being surrounded by boundary lipids, interacting with hydrophobic surfaces of the peptide portions. It is true for all single-spanning bitopic membrane proteins. For multi-spanning polytopic membrane proteins, however, some transmembrane peptide portions could remain in the membrane lipid bilayer without having to associate with boundary lipids: instead, they art stabilized by the rest of peptide portions of the molecules.抄録全体を表示PDF形式でダウンロード (65K)
トピックス
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岡野 俊行, 深田 吉孝1999 年 39 巻 4 号 p. 246-249
発行日: 1999/07/25
公開日: 2000/04/12
ジャーナル フリーPDF形式でダウンロード (114K) -
- 見直される“SNARE仮説” -佐藤 健1999 年 39 巻 4 号 p. 250-253
発行日: 1999/07/25
公開日: 2000/04/12
ジャーナル フリーPDF形式でダウンロード (130K)
実験技術
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平尾 一郎1999 年 39 巻 4 号 p. 254-257
発行日: 1999/07/25
公開日: 2000/04/12
ジャーナル フリーPDF形式でダウンロード (94K)
ひとくふう
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渡辺 功一, 作山 孝法, フーラハン 美由紀, 太田 善浩1999 年 39 巻 4 号 p. 258-260
発行日: 1999/07/25
公開日: 2000/04/12
ジャーナル フリーPDF形式でダウンロード (55K) -
林 文夫1999 年 39 巻 4 号 p. 261-263
発行日: 1999/07/25
公開日: 2000/04/12
ジャーナル フリーPDF形式でダウンロード (139K)
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