Stenosis of the upper airway caused by any pathology decreases normal ventilation, leading to serious disturbance in gas exchange.
1) Partitioning of the upper airway resistance.
The normal value of the upper airway resistance under quiet breathing is around 1.5cmH
2O/L/sec., in which two-thirds are made by the nose and one-third by the pharyngo-larynx. When the mobility of the hemilarynx is disturbed, the value of laryngeal resistance may exceed that of nasal resistance; however, there are no signs of dyspnea. In case of bilateral laryngeal paralysis, dyspnea always appears, the resistance of which reaches more than 6cmH
2O/L/sec.
2) Respiratory function in laryngeal stenosis.
Various respiratory function tests were performed on laryngeal diseases. On the relationgraph between VC% and FEV
1.0% these data of laryngeal stenosis dropped in the territory showing pathologic changes, either obstructive or restrictive. In case of bilateral laryngeal paralysis, the MEFV curve showed diminished peak flow with a plateau-formation, a characteristic pattern of upper airway stenosis. In other cases such changes of the curve were not evident.
3) Respiratory gas analysis.
Continuous FO
2 and FCO
2 measurements were performed by sampling the respiratory gas through the tracheostoma. In bilateral laryngeal paralysis, SaO
2 and PO
2 values measured percutaneously showed slightly lower value than normal. When a pneumotachograph-mask is applied to record the respiratory pattern, these values decrease further, probably due to additional airway resistance and dead space.
In conclusion, upper airway stenosis not only of severe degree, but of a moderate degree as to feel slight difficulty in breathing, may affect the pulmonary function results. A tracheostomy or successful laryngeal or tracheal reconstruction will recover the normal ventilation.
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