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Volume 35 (1984)
- Issue 6 Pages 391-
- Issue 5 Pages 345-
- Issue 4 Pages 281-
- Issue 3 Pages 229-
- Issue 2 Pages 65-
- Issue 1 Pages 1-
Volume 35, Issue 6
Displaying 1-7 of 7 articles from this issue
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Motohide Sasamoto, Kenichi Yamaki, Ikuo Yamakawa, Tatsuo Satake1984 Volume 35 Issue 6 Pages 391-398
Published: December 10, 1984
Released on J-STAGE: February 22, 2010
JOURNAL FREE ACCESSMucus plug formation in the airways often causes atelectasis, subsequently infection and respiratory distress. We devised a new method to detect mucus plug formation in the airway and performed an experimental study with this method to elucidate the role of airway constriction and mucociliary transport system in mucus plug formation.
The results were as follows:
1. Mucus plug formation was accelerated by airway constriction, excessive secretion of mucus and an impairment of mucociliary function.
2. Once mucus plug was formed, it often remained, even when airway constriction was relieved.
3. Mucociliary transport was impaired by airway constriction and recovered by relieving constriction.
These results clarified the mechanism of mucus plug formation. Moreover, they suggest that relieving the airway constriction, accelerating the mucociliary transport and cough function, and modulating the quality and the quantity of mucus are required for the prevention and the treatment of mucus plug.View full abstractDownload PDF (5580K) -
Takashi Horie, Akiharu Ohkuma, Tomoji Inazawa, Satoshi Enomoto, Tsunet ...1984 Volume 35 Issue 6 Pages 399-405
Published: December 10, 1984
Released on J-STAGE: February 22, 2010
JOURNAL FREE ACCESSEffect of various drugs on histamine induced bronchoconstriction and exercise-induced asthma (EIA) has been examined by many investigators, however, results are inconsistent. The purpose of the present study was to investigate the effect of sodium cromoglycate (SCG) on histamine inhalation challenge with 12 asthmatics and on EIA with 15 patients who developed bronchoconstriction following exercise. Cumulative doses of histamine to produce the 20% reduction of forced expiratory volume in one second (PD20FEV1) were significantly decreased in asthmatics, however, the slopes of dose response curves (reactivity) varied significantly and were not differed from those of normal subjects. The reproducibility of dose-respons curves obtained from 10 patients was very good. Pretreatment with SCG did not affect both PD20FEV1 and slope of doserespons curves in asthmatics. Cases of EIA were divided to responders who had V50 larger than 120% and non-responders who had V50 smaller than 120% based upon the flow-volume curves of air and HeO2 obtained at 5 minutes after exercise. Responders (8 cases) showed relatively mild airway obstruction following exertion which tended to return to pre-exercise levels with time. On the other hand, non-responders (7 cases) developed significant post-exertional bronchoconstriction which did not recover without medication. SCG protected EIA moderately and/or markedly except for 3 cases of responder in whom no protection was observed.
These results indicate that the mechanism to induce bronchospasms was different between histamine challenge test and EIA.View full abstractDownload PDF (755K) -
Hiroko Yonekawa, Shinichi Kato, Rieko Nakanishi, Tadahide Nishimae, Hi ...1984 Volume 35 Issue 6 Pages 406-416
Published: December 10, 1984
Released on J-STAGE: February 22, 2010
JOURNAL FREE ACCESSA case of the laryngeal amyloidosis, a 23-year-old female complaining of hoarseness during 12 years, was reported. Recently, she has consulted our clinic because of shortness of breath on exertion and difficulty in swallowing.
Indirect laryngoscopy revealed large yellow-red masses occupying nearly the whole space of the larynx, and their pedicles were not clearly found. Four tumor masses on the false cords and ventricular spaces on both sides were successfully extirpated through laryngofissure, and buccal mucosae were grafted on the defective site of the laryngeal mucous membrane. Histopathological findings of the tumors showed laryngeal amyloidosis. Amyloid deposits were also found in the nasopharyngeal regions, including the soft palate and the orifice of the eustachian tube. Nasopharyngeal amyloid masses are observed at regular intervals without a surgical removal.View full abstractDownload PDF (9987K) -
Takeo Hotate, Kohji Asakura, Shigeo Sambe, Kenji Morimoto, Akikatsu Ka ...1984 Volume 35 Issue 6 Pages 417-425
Published: December 10, 1984
Released on J-STAGE: February 22, 2010
JOURNAL FREE ACCESSThree cases of malignant change from precancerous lesions, two laryngeal keratoses and one laryngeal papilloma, are reported.
Case 1 was a 67-year-old man. Malignant change was recognized three and a half years after he had noticed hoarseness and laryngeal dryness. He was treated by irradiation of 5, 000rads and thereafter cancer cells disappeared.
Case 2 was a 57-year-old man. His laryngeal keratosis developed into a malignancy one year and ten months after he had recognized hoarseness and laryngeal discomfort. He was treated by irradiation of 6, 500rads, but cancer cells remained. So he underwent a total laryngectomy.
Case 3 was a 50-year-old man. Malignant change was noted in the laryngeal papilloma, which had been diagnosed one year and eight months before. As he noticed dyspnea due to papillomatous masses on both vocal cords, a total laryngectomy was performed.
According to our experience and literature review, we concluded as follows:
1) Laryngeal keratosis, especially with a reccurent tendency should be treated by a conservative surgical resection (e. g. laryngomicrosurgery). In case of malignant change, an irradiation therapy is mandatory to be done before an advanced surgical approach was performed.
2) Laryngeal papilloma should be also treated by a conservative surgical method. In this case an irradiation therapy would be contraindicated.View full abstractDownload PDF (9307K) -
Hitoshi Hentona, Shoji Takoda, Norihiko Ishikawa, Wataru Nishijima, Ki ...1984 Volume 35 Issue 6 Pages 427-431
Published: December 10, 1984
Released on J-STAGE: February 22, 2010
JOURNAL FREE ACCESSStenosis of a permanent tracheostoma may be caused by excessive scar tissues, keloid formation, excessive fatty tissues, defective tracheal rings or recurrent tumor. It was also assumed that high tension at the site of through-and-through sutures may cause stenosis. Based on the above concept, a new surgical method was devised to avoid excessive tension at the stomal margin and to prevent the invasion of fatty tissues to the site of sutures. The new method-denuded flap tracheostomy-was applied to 13 cases following laryngectomy and satisfactory results were obtained.View full abstractDownload PDF (4772K) -
Keiichi Kontani, Toru Enokibori, Naoki Yamashita, Shuichi Matsuno, Aki ...1984 Volume 35 Issue 6 Pages 432-437
Published: December 10, 1984
Released on J-STAGE: February 22, 2010
JOURNAL FREE ACCESSLung carcinoma infiltrating into the esophagus has been considered hardly resectable. In fact, there has been no case report of successful surgical intervention for lung carcinoma invading of the esophagus.
Recently, a 64-year-old man who presented himself with dysphagia due to direct extension of lung carcinoma into the esophagus, was operated on in our department. A preoperative barium esophagram revealed narrowing of the esophagus with normal mucosa. Therefore, pneumonectomy could be performed for removal of the tumor and esophagomyotomy could be made for release from stenosis of the esophagus after intensive irradiation.
Dysphagia disappeared and there is no recurrence for four months after the treatment.
A combination of both esophagomyotomy and adjuvant irradiation is advisable in case with lung carcinoma infiltrating into the esophagus to release from stenosis of the esophagus, because this procedure is of lower surgical risk with fewer postoperative complications than combined resection of the esophagus with the lung.View full abstractDownload PDF (7349K) -
Satoshi Hasegawa, Yasuo Watanabe, Minoru Ishida, Hiromitsu Tamaki, Tor ...1984 Volume 35 Issue 6 Pages 438-441
Published: December 10, 1984
Released on J-STAGE: February 22, 2010
JOURNAL FREE ACCESSA statistical study was conducted on the cases of foreign bodies handled in an emergency ENT clinic during the period from 1978 through 1983.
The results were as follows;
1. During the 6 year period, 473 patients (2.1%) out of a total of 22408 patients presented with foreign bodies.
2. The locations of the foreign bodies were; 219 cases in the nose, 206 in the pharynx, 28 in the larynx, 1 in the trachea and 19 in the esophagus.
3. More than 50% of the 473 cases were infants. Of the cases having foreign bodies in the nose, 90% were infants.
4. One hundred and nineteen (54.4%) of the 219 foreign bodies found in the nose were spheroidal. Two hundred and sixteen (92.3%) of the 234 foreign bodies found in the larynx and pharynx were fish bones. Thirteen (68.4%) of the 19 foreign bodies found in the esophagus were coins, and in 9 of the 13 cases coins were lodged at the entrance of the esophagus. The foreign bodies found in the trachea of one case were beans.
5. Two hundred and seventy seven (58.6%) of the 473 cases were treated within 6 hours.View full abstractDownload PDF (397K)
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